Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Jiming Kong"'
Autor:
Teng Guan, Ying Guo, Ting Zhou, Qiang Yu, Jingyi Sun, Baoliang Sun, Guohui Zhang, Jiming Kong
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Neural stem cells (NSCs), especially human NSCs, undergo cellular senescence characterized by an irreversible proliferation arrest and loss of stemness after prolonged culture. While compelling correlative data have been generated
Externí odkaz:
https://doaj.org/article/2b0ee2b2a58a4ce4bd8db50a5c40d88a
Autor:
Ying Guo, Teng Guan, Qiang Yu, Nitesh Sanghai, Kashfia Shafiq, Meiyu Li, Xin Jiao, Donghui Na, Guohui Zhang, Jiming Kong
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102972- (2024)
Oxidative stress (OS) is regarded as the dominant theory for aging. While compelling correlative data have been generated to support the OS theory, a direct cause-and-effect relationship between the accumulation of oxidation-mediated damage and aging
Externí odkaz:
https://doaj.org/article/71339a3cab134c6e9035e0a551d0a088
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108518- (2023)
Summary: Myelin sheath in the central nervous system (CNS) is essential for efficient action potential conduction. Microglia, the macrophages in the CNS, are suggested to regulate myelin development. However, the specific involvement of microglia in
Externí odkaz:
https://doaj.org/article/c884fe4ebc184856a125216bc47b67ff
Publikováno v:
ASN Neuro, Vol 15 (2023)
Myelination contributes not only to the rapid nerve conduction but also to axonal insulation and protection. In the central nervous system (CNS), the initial myelination features a multistep process where oligodendrocyte precursor cells undergo proli
Externí odkaz:
https://doaj.org/article/27bd27ea2ea14d8fb660694ff91410c1
Autor:
WeiBing Wang, Zhen Liu, BaoSheng Jing, HaiMin Mai, Hong Jiao, Teng Guan, DanGui Chen, JiMing Kong, Tao Pan
Publikováno v:
Dose-Response, Vol 20 (2022)
Background Borojó (Borojoa patinoi Cuatrec) fruit has recently been shown to have a variety of health benefit, but the mechanisms have been little studied. The aim of this study was to investigate the effect of 4,8-dicarboxyl-8,9-iridoid-1-glycoside
Externí odkaz:
https://doaj.org/article/e336302b7a79437f9ea73beeea7ed31e
Autor:
Teng Guan, Ying Guo, Chengren Li, Ting Zhou, Qiang Yu, Chaoxian Yang, Guohui Zhang, Jiming Kong
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1872 (2022)
Neurodegeneration can benefit from ischemic preconditioning, a natural adaptive reaction to sublethal noxious stimuli. Although there is growing interest in advancing preconditioning to preserve brain function, preconditioning is not yet considered r
Externí odkaz:
https://doaj.org/article/525f268f1560479e9cdfcaee57da6bb7
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Traditional therapeutics targeting Alzheimer’s disease (AD)-related subpathologies have so far proved ineffective. Drug repurposing, a more effective strategy that aims to find new indications for existing drugs against other diseases,
Externí odkaz:
https://doaj.org/article/aee26e15a4854122b6f7ae81ec0107af
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Delayed neurologic sequelae (DNS) are recurrent–transient neuropsychiatric consequences of carbon monoxide (CO) intoxication. Pathologically DNS features damages to the brain white matter. Here we test a hypothesis that direct cytotoxicity of CO to
Externí odkaz:
https://doaj.org/article/5bf3f2c68ecc4020ab4283f1bcfb20ad
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 297 (2022)
The encapsulation of cells with various polyelectrolytes through layer-by-layer (LbL) has become a popular strategy in cellular function engineering. The technique sprang up in 1990s and obtained tremendous advances in multi-functionalized encapsulat
Externí odkaz:
https://doaj.org/article/fcd8d918c8f9417683ad8da1c37cb40b
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Diffuse axonal injury (DAI) is characterized by delayed axonal disconnection. Although the effect of DAI on axonal pathology has been well documented, there is limited information regarding the role of myelin in the pathogenesis of DAI. We used a mod
Externí odkaz:
https://doaj.org/article/3970deffdc11489ca532b8213ba23ec1