Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jimena Tosello"'
Autor:
Saumya Kumar, Afonso P. Basto, Filipa Ribeiro, Silvia C. P. Almeida, Patricia Campos, Carina Peres, Nadia Pulvirenti, Sarwah Al-Khalidi, Anna Kilbey, Jimena Tosello, Eliane Piaggio, Momtchilo Russo, Margarida Gama-Carvalho, Seth B. Coffelt, Ed W. Roberts, Jens Geginat, Helena F. Florindo, Luis Graca
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-21 (2024)
Abstract Effective antibody responses are essential to generate protective humoral immunity. Different inflammatory signals polarize T cells towards appropriate effector phenotypes during an infection or immunization. Th1 and Th2 cells have been asso
Externí odkaz:
https://doaj.org/article/b1ab6f0616b246af8630d5bef2fc7871
Autor:
Elisa Bonnin, Maria Rodrigo Riestra, Federico Marziali, Rafael Mena Osuna, Jordan Denizeau, Mathieu Maurin, Juan Jose Saez, Mabel Jouve, Pierre-Emmanuel Bonté, Wilfrid Richer, Fabien Nevo, Sebastien Lemoine, Nicolas Girard, Marine Lefevre, Edith Borcoman, Anne Vincent-Salomon, Sylvain Baulande, Helene D. Moreau, Christine Sedlik, Claire Hivroz, Ana-Maria Lennon-Duménil, Jimena Tosello Boari, Eliane Piaggio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Regulatory T cells (Tregs) are plastic cells playing a pivotal role in the maintenance of immune homeostasis. Tregs actively adapt to the microenvironment where they reside; as a consequence, their molecular and functional profiles differ am
Externí odkaz:
https://doaj.org/article/7c63a70c3d6a473080accb289f96f5ea
Autor:
Constanza Rodriguez, Cintia L. Araujo Furlan, Jimena Tosello Boari, Sabrina N. Bossio, Santiago Boccardo, Laura Fozzatti, Fernando P. Canale, Cristian G. Beccaria, Nicolás G. Nuñez, Danilo G. Ceschin, Eliane Piaggio, Adriana Gruppi, Carolina L. Montes, Eva V. Acosta Rodríguez
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTIL-17 immune responses in cancer are controversial, with both tumor-promoting and tumor-repressing effects observed. To clarify the role of IL-17 signaling in cancer progression, we used syngeneic tumor models from different tissue origins. W
Externí odkaz:
https://doaj.org/article/6e650540fa944ac7991547e49fd241e1
Autor:
Sabrina N. Bossio, Carolina Abrate, Jimena Tosello Boari, Constanza Rodriguez, Fernando P. Canale, María C. Ramello, Valentina Brunotto, Wilfrid Richer, Dario Rocha, Christine Sedlik, Anne Vincent-Salomon, Edith Borcoman, Andres Del Castillo, Adriana Gruppi, Elmer Fernandez, Eva V. Acosta Rodríguez, Eliane Piaggio, Carolina L. Montes
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTConventional CD4+ T (Tconv) lymphocytes play important roles in tumor immunity; however, their contribution to tumor elimination remains poorly understood. Here, we describe a subset of tumor-infiltrating Tconv cells characterized by the expr
Externí odkaz:
https://doaj.org/article/c2c7022bc10c4d4d97766bb302e5a761
Autor:
Melisa Gorosito Serrán, Facundo Fiocca Vernengo, Laura Almada, Cristian G. Beccaria, Yamila Gazzoni, Pablo F. Canete, Jonathan A. Roco, Jimena Tosello Boari, Maria Cecilia Ramello, Ellen Wehrens, Yeping Cai, Elina I. Zuniga, Carolina L. Montes, Ian A. Cockburn, Eva V. Acosta Rodriguez, Carola G. Vinuesa, Adriana Gruppi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
During infections with protozoan parasites or some viruses, T cell immunosuppression is generated simultaneously with a high B cell activation. It has been described that, as well as producing antibodies, plasmablasts, the differentiation product of
Externí odkaz:
https://doaj.org/article/e2cf7f337a5340039ee73c984b6bf218
Autor:
Nicolas Gonzalo Núñez, Jimena Tosello Boari, Rodrigo Nalio Ramos, Wilfrid Richer, Nicolas Cagnard, Cyrill Dimitri Anderfuhren, Leticia Laura Niborski, Jeremy Bigot, Didier Meseure, Philippe De La Rochere, Maud Milder, Sophie Viel, Delphine Loirat, Louis Pérol, Anne Vincent-Salomon, Xavier Sastre-Garau, Becher Burkhard, Christine Sedlik, Olivier Lantz, Sebastian Amigorena, Eliane Piaggio
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Tumor-draining lymph nodes are often the first site of metastasis in breast cancer patients. Here, the authors show that metastatic lymph nodes are characterized by the accumulation of suppressive regulatory T cells with a distinct phenotype compared
Externí odkaz:
https://doaj.org/article/fa92c2f7fbcd485fb13c6e8b461e9fce
Autor:
Maria C. Ramello, Nicolás G. Núñez, Jimena Tosello Boari, Sabrina N. Bossio, Fernando P. Canale, Carolina Abrate, Nicolas Ponce, Andrés Del Castillo, Marta Ledesma, Sophie Viel, Wilfrid Richer, Christine Sedlik, Carolina Tiraboschi, Marcos Muñoz, Daniel Compagno, Adriana Gruppi, Eva V. Acosta Rodríguez, Eliane Piaggio, Carolina L. Montes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Senescent T cells have been described during aging, chronic infections, and cancer; however, a comprehensive study of the phenotype, function, and transcriptional program of this T cell population in breast cancer (BC) patients is missing. Compared t
Externí odkaz:
https://doaj.org/article/33ccf8dcf8ac4fcdacbeebf8c5960cbb
Autor:
Facundo Fiocca Vernengo, Cristian G. Beccaria, Cintia L. Araujo Furlan, Jimena Tosello Boari, Laura Almada, Melisa Gorosito Serrán, Yamila Gazzoni, Carolina L. Montes, Eva V. Acosta Rodríguez, Adriana Gruppi
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Treatment with anti-CD20, used in many diseases in which B cells play a pathogenic role, has been associated with susceptibility to intracellular infections. Here, we studied the effect of anti-CD20 injection on CD8+ T cell immunity using an
Externí odkaz:
https://doaj.org/article/cb2cab0b6ad84a64815d58f1f221012c
Autor:
Cristian Gabriel Beccaria, María Carolina Amezcua Vesely, Facundo Fiocca Vernengo, Ricardo Carlos Gehrau, María Cecilia Ramello, Jimena Tosello Boari, Melisa Gorosito Serrán, Juan Mucci, Eliane Piaggio, Oscar Campetella, Eva Virginia Acosta Rodríguez, Carolina Lucía Montes, Adriana Gruppi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Germinal center (GC) is where B cells interact with other immune cells for optimal induction of antibody responses. Here the authors show that galectin-3 regulates GC development by modulating interferon-γ and B cell-intrinsic signaling, such that g
Externí odkaz:
https://doaj.org/article/e56f9c7562ff48e1b8ef2534da1247d2
Autor:
Natalia S Baez, Fabio Cerbán, Constanza Savid-Frontera, Deborah L Hodge, Jimena Tosello, Eva Acosta-Rodriguez, Laura Almada, Adriana Gruppi, Maria Estefania Viano, Howard A Young, Maria Cecilia Rodriguez-Galan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007456 (2019)
Innate CD8+ T cells express a memory-like phenotype and demonstrate a strong cytotoxic capacity that is critical during the early phase of the host response to certain bacterial and viral infections. These cells arise in the thymus and depend on IL-4
Externí odkaz:
https://doaj.org/article/43f03edd76ac4cb3906db169ea8f71ab