Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Jimena Ospina"'
1
Akademický článek
Hybrid Cyclobutane/Proline-Containing Peptidomimetics: The Conformational Constraint Influences Their Cell-Penetration Ability
Autor: Ona Illa, Jimena Ospina, José-Emilio Sánchez-Aparicio, Ximena Pulido, María Ángeles Abengozar, Nerea Gaztelumendi, Daniel Carbajo, Carme Nogués, Luis Rivas, Jean-Didier Maréchal, Miriam Royo, Rosa M. Ortuño
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 10, p 5092 (2021)
A new family of hybrid β,γ-peptidomimetics consisting of a repetitive unit formed by a chiral cyclobutane-containing trans-β-amino acid plus a Nα-functionalized trans-γ-amino-l-proline joined in alternation were synthesized and evaluated as cell
Externí odkaz: https://doaj.org/article/581a1c699e134a00ba99da9a678902a5
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2
Akademický článek
Chiral Cyclobutane-Containing Cell-Penetrating Peptides as Selective Vectors for Anti-Leishmania Drug Delivery Systems
Autor: Ona Illa, José-Antonio Olivares, Nerea Gaztelumendi, Laura Martínez-Castro, Jimena Ospina, María-Ángeles Abengozar, Giuseppe Sciortino, Jean-Didier Maréchal, Carme Nogués, Míriam Royo, Luis Rivas, Rosa M. Ortuño
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 20, p 7502 (2020)
Two series of new hybrid γ/γ-peptides, γ-CC and γ-CT, formed by (1S,2R)-3-amino-2,2,dimethylcyclobutane-1-carboxylic acid joined in alternation to a Nα-functionalized cis- or trans-γ-amino-l-proline derivative, respectively, have been synthesiz
Externí odkaz: https://doaj.org/article/976a732b116b4ee8b16dc87fd4099408
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3
Hybrid Cyclobutane/Proline-Containing Peptidomimetics: The Conformational Constraint Influences Their Cell-Penetration Ability
Autor: Jimena Ospina, Carme Nogués, Daniel Carbajo, Jean-Didier Maréchal, José-Emilio Sánchez-Aparicio, Ona Illa, María Ángeles Abengózar, Nerea Gaztelumendi, Miriam Royo, Ximena Pulido, Rosa M. Ortuño, Luis Rivas
Publikováno v: International Journal of Molecular Sciences
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 22, Iss 5092, p 5092 (2021)
Volume 22
Issue 10
A new family of hybrid β,γ-peptidomimetics consisting of a repetitive unit formed by a chiral cyclobutane-containing trans-β-amino acid plus a Nα-functionalized trans-γ-amino-l-proline joined in alternation were synthesized and evaluated as cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b7955fcb4435b96c469649868ccd22
http://europepmc.org/articles/PMC8151717
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4
Chiral Cyclobutane-Containing Cell-Penetrating Peptides as Selective Vectors for Anti-Leishmania Drug Delivery Systems
Autor: Carme Nogués, María-Ángeles Abengozar, Ona Illa, Luis Rivas, Jean-Didier Maréchal, Giuseppe Sciortino, Nerea Gaztelumendi, José Antonio Olivares, Laura Martínez-Castro, Miriam Royo, Rosa M. Ortuño, Jimena Ospina
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
International Journal of Molecular Sciences, Vol 21, Iss 7502, p 7502 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
Two series of new hybrid &gamma
/&gamma
peptides, &gamma
CC and &gamma
CT, formed by (1S,2R)-3-amino-2,2,dimethylcyclobutane-1-carboxylic acid joined in alternation to a N&alpha
functionalized cis- or trans-&gamma
amino-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea51ef536f10530f98f4779cf926f0a6
https://ddd.uab.cat/record/233888
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5
Stereoselective synthesis of highly branched chiral cyclobutane-cored triamines and their conjugation to Gd-DOTA
Autor: Ona Illa, Rosa M. Ortuño, Raquel Gutiérrez-Abad, Jimena Ospina, Vicenç Branchadell, Silvia Lope-Piedrafita
Publikováno v: Tetrahedron. 71:8085-8095
Several chiral cyclobutane-containing chemical platforms were synthesized in a stereoselective manner starting from (−)-verbenone as a suitable precursor. These compounds bear three orthogonally protected amine functions, two of them on side-chain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2dc2e085ba0006defafbc148cfe58929
https://doi.org/10.1016/j.tet.2015.08.044
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6
Divergent synthetic routes to biologically relevant types of compounds: chiral polyfunctional γ-lactams and amino acids
Autor: Rosa M. Ortuño, Jimena Ospina, Albertina G. Moglioni, Ona Illa, Àlex Mor, Jordi Aguilera
Divergent and versatile synthetic routes leading to the title compounds are described. They start from a common chiral precursor derived from (−)-(S)-verbenone and afford polyfunctional γ-lactams and γ- and ε-amino acids. The cyclobutane moiety
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1f9854b2b8a3e869c5caa93437efb8
http://www.sciencedirect.com/science/article/pii/S0040402014010138?via=ihub
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7
New chiral polyfunctional cyclobutane derivatives from (-)-verbenone: Possible surfactant behaviour
Autor: Jimena Ospina, Ramon Pons, Alessandro Sorrenti, Ona Illa, Rosa M. Ortuño
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
New enantiopure cyclobutane derivatives have been synthesized from a chiral precursor derived from (-)-verbenone. The cyclobutane moiety acts as a chiral platform to afford a γ-amino acid function in a branched side-chain containing an additional st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2325688a2441e75ddb2418d891e60d5f
http://hdl.handle.net/10261/128741
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