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Pharmacokinetics and Pharmacodynamics in HIV Prevention; Current Status and Future Directions: A Summary of the DAIDS and BMGF Sponsored Think Tank on Pharmacokinetics (PK)/Pharmacodynamics (PD) in HIV Prevention

Autor: Joseph, Romano, Angela, Kashuba, Stephen, Becker, James, Cummins, Jim, Turpin, Fulvia, Veronese, Sheryl, Zwerski

Publikováno v: AIDS Research and Human Retroviruses. 29:1418-1427

Thirty years after its beginning, the HIV/AIDS epidemic is still raging around the world. According to UNAIDS, in 2011 alone 1.7M deaths were attributable to AIDS, and 2.5M people were newly infected by the virus. Despite the success in treating HIV-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d69118c1a834c703177d2964801129
https://doi.org/10.1089/aid.2013.0122

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Anti-AIDS Agents. 52. Synthesis and Anti-HIV Activity of Hydroxymethyl (3‘R,4‘R)-3‘,4‘-Di-O-(S)-camphanoyl-(+)-cis-khellactone Derivatives

Autor: Carl T. Wild, Donglei Yu, Lan Xie, Jim Turpin, Graham Allaway, Kuo Hsiung Lee, Philip C. Smith

Publikováno v: Journal of Medicinal Chemistry. 47:756-760

To enhance the water solubility and oral bioavailability of DCK analogues, 12 new mono- and disubstituted (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) analogues were synthesized and evaluated for inhibition of HIV-1 replication in H9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6490069ca1481210b04abb55fdbc48
https://doi.org/10.1021/jm030416y

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Effects of Liposomal Amphotericin B on Human Peripheral Blood Monocytes and Lymphocytes

Autor: Charles Gschwind, Jeane P. Hester, James M. Reuben, Gabriel Lopez-Berestein, Jim Turpin

Publikováno v: Journal of Liposome Research. 1:81-92

The effects of free amphotericin B (AmpB) and liposome-encapsulated amphotericin B (L-AmpB) on normal human peripheral blood monocytes (HPBM) and lymphocytes were studied. L-AmpB did not reduce HPBM H2O2-generating capacity even at doses of 100 µg/m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acfb8f7fa7810b40a56effffd4566164
https://doi.org/10.3109/08982108809035983

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Induction of Tissue Transglutaminase in Human Peripheral Blood Monocytes by Intracellular Delivery of Retinoids

Autor: Kapil Mehta, Jim Turpin, Gabriel Lopez-Berestein

Publikováno v: Journal of Leukocyte Biology. 41:341-348

Human peripheral blood monocytes (HPBM) from normal donors, isolated by counter-current centrifugal elutriation into two subpopulations, showed no significant difference in their ability to differentiate in vitro into macrophages as determined by ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1812818c872d8e36aab689e513623369
https://doi.org/10.1002/jlb.41.4.341

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