Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jim Koh"'
Autor:
Emma E. Furth, Karen S. Gustafson, Charlotte Y. Dai, Steven L. Gibson, Paul Menard-Katcher, Tina Chen, Jim Koh, Greg H. Enders
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 6, Pp 429-436 (2006)
p16INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in vivo in response to replicative stress, we examined p16 expression in tissues from human u
Externí odkaz:
https://doaj.org/article/d9f9ddbb80d84af1adfff90997b74486
Autor:
Eleanor J. Tyler, Ryan Wallis, Robert Lowe, Martha R. Stampfer, Cleo L. Bishop, Bethany K. Hughes, Ana Gutierrez del Arroyo, Michael P. Philpott, James C. Garbe, Jim Koh
Publikováno v:
Aging Cell
Aging cell, vol 20, iss 3
Aging cell, vol 20, iss 3
Senescence, a state of stable growth arrest, plays an important role in ageing and age‐related diseases in vivo. Although the INK4/ARF locus is known to be essential for senescence programmes, the key regulators driving p16 and ARF transcription re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734ae8cda37b2be024a179867c806cbb
http://europepmc.org/articles/PMC7963333
http://europepmc.org/articles/PMC7963333
Autor:
Greg H. Enders, Steven L. Gibson, Karen S. Gustafson, Jim Koh, Emma E. Furth, Paul Menard-Katcher, Tina Chen, Charlotte Y. Dai
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 6, Pp 429-436 (2006)
p16INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in vivo in response to replicative stress, we examined p16 expression in tissues from human u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8f58ed1796795e42c3135159d9414d
http://www.sciencedirect.com/science/article/pii/S1476558606800254
http://www.sciencedirect.com/science/article/pii/S1476558606800254
Autor:
Yoshiro Niitsu, Charlotte Y. Dai, Greg H. Enders, Emma E. Furth, Rosemarie Mick, Tetsuji Takayama, Jim Koh
Publikováno v:
Gastroenterology. 119:929-942
Background & Aims: p16 INK4a is a cell cycle inhibitor and a major tumor-suppressor protein, but the regulation of p16 INK4a is poorly understood and the physiologic settings in which it exerts its antiproliferative effects are unknown. A role for p1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b595954acf880c2d121b28451cabfa3a
https://doi.org/10.1053/gast.2000.17952
https://doi.org/10.1053/gast.2000.17952
Autor:
Elizabeth Hatzimasoura, Cleo L. Bishop, James C. Garbe, Delphine Fessart, Jim Koh, Ann-Marie H. Bergin, Viola Borgdorff, David H. Beach, Martha R. Stampfer
Publikováno v:
Molecular cell. 40(4)
In a genome-wide siRNA analysis of p16(INK4a) (p16) modulators, we identify the Hedgehog (Hh) pathway component SUFU and formally demonstrate that Hh signaling promotes mitogenesis by suppression of p16. A fragment of the Hh-responsive GLI2 transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392c5a5d474742de1e152e5163d969ae
https://pubmed.ncbi.nlm.nih.gov/21095584
https://pubmed.ncbi.nlm.nih.gov/21095584
Autor:
Lucía Pérez-Carbonell, Adela Castillejo, Xavier Llor, Rodrigo Jover, Cristina Alenda, Artemio Payá, Estefanía Rojas, Alfredo Carrato, Montserrat Andreu, José Luis Soto, Greg H. Enders, Carmen Guillen, Víctor Manuel Barberá, Susana Benlloch, Antoni Castells, Jim Koh
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 15(9)
Purpose: Immunohistochemistry for mismatch repair proteins has shown utility in the identification of Lynch syndrome, but majority of tumors with loss of MLH1 expression are due to sporadic hypermethylation of the MLH1 promoter. These tumors can also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfea232122504de1f5693c96d647155b
https://pubmed.ncbi.nlm.nih.gov/19383812
https://pubmed.ncbi.nlm.nih.gov/19383812
Autor:
Jim Koh, M. Lisa Yaremko, John Hart, E. Brunt, Robert A. Anders, Marc Bissonnette, Thomas A. Brasitus
Publikováno v:
Gastroenterology. 118:A908
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44cb274e04bf8473b76de3d8aa89ff00
https://doi.org/10.1016/s0016-5085(00)85764-9
https://doi.org/10.1016/s0016-5085(00)85764-9