Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jim H Veldhuis"'
Autor:
G Wayne Brodland, Jim H Veldhuis, Steven Kim, Matthew Perrone, David Mashburn, M Shane Hutson
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99116 (2014)
Mechanical forces play a key role in a wide range of biological processes, from embryogenesis to cancer metastasis, and there is considerable interest in the intuitive question, "Can cellular forces be inferred from cell shapes?" Although several gro
Externí odkaz:
https://doaj.org/article/49461200d7c840028c9d4c3ed581413e
Autor:
G Wayne Brodland, Jim H Veldhuis
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44281 (2012)
Although it may seem obvious that mechanical forces are required to drive metastatic cell movements, understanding of the mechanical aspects of metastasis has lagged far behind genetic and biochemical knowledge. The goal of this study is to learn abo
Externí odkaz:
https://doaj.org/article/bbb749e55f76477ab02213bbf8ae8085
Publikováno v:
Clinical Biomechanics. 56:11-17
Background Disc height loss and osteophytes change the local mechanical environment in the spine; while previous research has examined kinematic dysfunction under degenerative change, none has looked at the influence of disc height loss and osteophyt
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering. 20:794-802
The motions of individual intervertebral joints can affect spine motion, injury risk, deterioration, pain, treatment strategies, and clinical outcomes. Since standard kinematic methods do not provide precise time-course details about individual verte
Elongated cells drive morphogenesis in a surface-wrapped finite element model of germband retraction
During Drosophila embryogenesis, the germband first extends to curl around the posterior end of the embryo, and then retracts back; however, retraction is not simply the reversal of extension. At a tissue level, extension is coincident with ventral f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5933851007be9b3b171b0d4586904a
Autor:
Neil M. Neumann, G. Wayne Brodland, Jim H. Veldhuis, Andrew J. Ewald, Matthew C. Perrone, Robert J. Huebner, Huiwang Zhan, Peter N. Devreotes
We sought to understand how cells collectively elongate epithelial tubes. We first used 3D culture and biosensor imaging to demonstrate that epithelial cells enrich Ras activity, phosphatidylinositol (3,4,5)-trisphosphate (PIP3), and F-actin to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314fe75596dd0db2925ac34f60221f4d
https://europepmc.org/articles/PMC5983037/
https://europepmc.org/articles/PMC5983037/
Publikováno v:
Biomechanics and Modeling in Mechanobiology
Computational models of cell–cell mechanical interactions typically simulate sorting and certain other motions well, but as demands on these models continue to grow, discrepancies between the cell shapes, contact angles and behaviours they predict
Autor:
Benoit Ladoux, Xavier Trepat, Vito Conte, G. Wayne Brodland, Julien Colombelli, Mukund Gupta, Agustí Brugués, José J. Muñoz, Ester Anon, Jim H. Veldhuis
Publikováno v:
Nature physics
Nature Physics
Nature Physics, Nature Publishing Group, 2014, 10 (9), pp.683-690. ⟨10.1038/nphys3040⟩
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
ResearcherID
Recercat. Dipósit de la Recerca de Catalunya
Universitat Jaume I
Nature Physics
Nature Physics, Nature Publishing Group, 2014, 10 (9), pp.683-690. ⟨10.1038/nphys3040⟩
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
ResearcherID
Recercat. Dipósit de la Recerca de Catalunya
Universitat Jaume I
A fundamental feature of multicellular organisms is their ability to self-repair wounds through the movement of epithelial cells into the damaged area. This collective cellular movement is commonly attributed to a combination of cell crawling and ‘
Elongated Cells Drive Morphogenesis in a Surface-Wrapped Finite-Element Model of Germband Retraction
Autor:
Jim H. Veldhuis, Monica E. Bennett, Holley E. Lynch, W. Tyler McCleery, G. Wayne Brodland, M. Shane Hutson, Xiaoyan Ma
Publikováno v:
Biophys J
During Drosophila embryogenesis, the germband first extends to curl around the posterior end of the embryo and then retracts back; however, retraction is not simply the reversal of extension. At a tissue level, extension is coincident with ventral fu
Autor:
Jim H. Veldhuis, G. Wayne Brodland
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 11:1137-1147
Early-stage embryos must reshape the tissues of which they are made into organs and other life-sustaining structures; and if non-mammalian embryos fail to complete these tasks before the energy provided by their yolk runs out, they die. The aim of th