Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jim Geiser"'
Autor:
Jim Geiser, Robert C De Lisle, David Finkelstein, Paul A Adlard, Ashley I Bush, Glen K Andrews
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72543 (2013)
BackgroundZinc deficiency due to poor nutrition or genetic mutations in zinc transporters is a global health problem and approaches to providing effective dietary zinc supplementation while avoiding potential toxic side effects are needed.Methods/pri
Externí odkaz:
https://doaj.org/article/83a06b4ef9494a5aab94221ac8aff609
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82149 (2013)
ZIP5 localizes to the baso-lateral membranes of intestinal enterocytes and pancreatic acinar cells and is internalized and degraded coordinately in these cell-types during periods of dietary zinc deficiency. These cell-types are thought to control zi
Externí odkaz:
https://doaj.org/article/7c89b091af7d4f3e934652a5bc218e4b
Publikováno v:
PLoS Genetics, Vol 8, Iss 6, p e1002766 (2012)
Mutations in the human Zip4 gene cause acrodermatitis enteropathica, a rare, pseudo-dominant, lethal genetic disorder. We created a tamoxifen-inducible, enterocyte-specific knockout of this gene in mice which mimics this human disorder. We found that
Externí odkaz:
https://doaj.org/article/6114b6f5a14b40c5a81eabaeb4b40098
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 294:R1474-R1481
Subfamily II of the solute carrier (Slc)39a family contains three highly conserved members (ZIPs 1–3) that share a 12-amino acid signature sequence present in the putative fourth transmembrane domain and function as zinc transporters in transfected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cabdd096ff1a8bae861ff3bbc5f48a
https://doi.org/10.1152/ajpregu.00130.2008
https://doi.org/10.1152/ajpregu.00130.2008
Autor:
Jodi Dufner-Beattie, Jim Geiser, Jennifer L. Peters, David E. Salt, Wenhao Xu, Glen K. Andrews, Brett Lahner
Publikováno v:
genesis. 45:339-352
Fourteen members of the Slc39a superfamily of metal ion uptake transporters have been identified in mice and humans, but the physiological functions of most remain obscure. Herein, we created mice with Zip2 (Slc39a2) genes in which the open reading f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7643ce8875b83c7746bb3ae1d7506a01
https://doi.org/10.1002/dvg.20297
https://doi.org/10.1002/dvg.20297
Publikováno v:
The Journal of Nutrition. 133:45-50
Herein, the function of pancreatic metallothionein (MT)-I during zinc deficiency in pregnancy was examined using transgenic mice, which constitutively express the mouse MT-I gene driven by the rat elastase I promoter. Pancreatic MT protein levels and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2a65deda295d010faf9d526e599d90
https://doi.org/10.1093/jn/133.1.45
https://doi.org/10.1093/jn/133.1.45
Autor:
Ashley I. Bush, Paul A. Adlard, Robert C. De Lisle, David Finkelstein, Glen K. Andrews, Jim Geiser
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e72543 (2013)
PLoS ONE, Vol 8, Iss 8, p e72543 (2013)
BackgroundZinc deficiency due to poor nutrition or genetic mutations in zinc transporters is a global health problem and approaches to providing effective dietary zinc supplementation while avoiding potential toxic side effects are needed.Methods/pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960ee222bc554a6c5303b43c6c562985
http://europepmc.org/articles/PMC3755987
http://europepmc.org/articles/PMC3755987
The mouse ZIP3 (SLC39A3) gene encodes an eight-transmembrane-domain protein that has been conserved in mammals and can function to transport zinc. To analyze the expression of ZIP3 in the early embryo and neonate and to determine its in vivo function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcff8c553dc314cc0cec0fe8ce289f3
https://europepmc.org/articles/PMC1156975/
https://europepmc.org/articles/PMC1156975/
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82149 (2013)
PLoS ONE
PLoS ONE
Background ZIP5 localizes to the baso-lateral membranes of intestinal enterocytes and pancreatic acinar cells and is internalized and degraded coordinately in these cell-types during periods of dietary zinc deficiency. These cell-types are thought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e586d209724d291a4ae8595418d8f1
https://doi.org/10.1371/journal.pone.0082149
https://doi.org/10.1371/journal.pone.0082149