Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Jim E. Cutler"'
Autor:
Jim E. Cutler, Kevin C. Hazen
The phenomenon of yeast (Y)⇄ mold (M) dimorphism (morphogenesis) has been observed for many years, but research in this area has intensified over the past 10 years. There are at least two major reasons for the current surge of interest. First, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd5fa74fa7201ce119eadfb9f9fe930c
https://doi.org/10.1201/9781003064879-12
https://doi.org/10.1201/9781003064879-12
Autor:
Hong Xin, Jonathan Cartmell, Justin J Bailey, Sebastian Dziadek, David R Bundle, Jim E Cutler
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35106 (2012)
Our research on pathogenesis of disseminated candidiasis led to the discovery that antibodies specific for Candida albicans cell surface β-1, 2-mannotriose [β-(Man)(3)] protect mice. A 14 mer peptide Fba, which derived from the N-terminal portion o
Externí odkaz:
https://doaj.org/article/9bfae7043e4f4b7f904b7b3944303dca
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22030 (2011)
Disseminated candidiasis is the third leading nosocomial blood stream infection in the United States and is often fatal. We previously showed that disseminated candidiasis was preventable in normal mice by immunization with either a glycopeptide or a
Externí odkaz:
https://doaj.org/article/03ba46e0e18144de8f42d6c4339696aa
Autor:
Jim E. Cutler, Hong Xin
Publikováno v:
Clinical and Vaccine Immunology. 18:1656-1667
Previously we showed that antibodies specific for the glycan β-1,2-mannotriose [β-(Man)3] on the cell surface ofCandida albicansprotect mice against disseminated candidiasis (H. Xin, S. Dziadek, D. R. Bundle, and J. E. Cutler, Proc. Natl. Acad. Sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1cbd5fa6845ca4a50405b8f009d042
https://doi.org/10.1128/cvi.05215-11
https://doi.org/10.1128/cvi.05215-11
Publikováno v:
Proceedings of the National Academy of Sciences. 105:13526-13531
The first fully synthetic glycopeptide vaccines against a fungal disease have been used to combat disseminated candidiasis in mice. Six T cell peptides found inCandida albicanscell wall proteins were selected by algorithm peptide epitope searches; ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e161145050beba48dfffad501408dd
https://doi.org/10.1073/pnas.0803195105
https://doi.org/10.1073/pnas.0803195105
Publikováno v:
Nature Reviews Microbiology. 5:13-28
The dramatic increase in fungal diseases in recent years can be attributed to the increased aggressiveness of medical therapy and other human activities. Immunosuppressed patients are at risk of contracting fungal diseases in healthcare settings and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e3ff3f9312c1b04519a416dcf8a1c4
https://doi.org/10.1038/nrmicro1537
https://doi.org/10.1038/nrmicro1537
Autor:
Jim E. Cutler, A. Brian Mochon
Publikováno v:
Medical Mycology. 43:97-115
The development of a useful Candida vaccine is a distinct possibility despite the fact that individuals with a lifetime of commensal sensitization do not develop sterile immunity to the organism. An effective Candida vaccine would be invaluable in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8af38f45b952416a01eab0cdc0935edf
https://doi.org/10.1080/13693780500035979
https://doi.org/10.1080/13693780500035979
Publikováno v:
Journal of Clinical Microbiology. 41:4252-4258
To improve objectivity and speed of current antifungal mold susceptibility testing, the yeast Rapid Susceptibility Assay (RSA) was adapted for Aspergillus species. The RSA is based on glucose utilization in the presence of an antifungal drug. Aspergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e783aff479856c8ebff5ee171d38f9
https://doi.org/10.1128/jcm.41.9.4252-4258.2003
https://doi.org/10.1128/jcm.41.9.4252-4258.2003
Autor:
Luigina Romani, Manfred Kopf, Roberta Gaziano, Claudia Montagnoli, Jim E. Cutler, Angela Bacci, Silvia Bozza, Joachim Morschhäuser, Lucia Pitzurra, Paolo Mosci
Publikováno v:
European Journal of Immunology. 33:1193-1204
Protective immunity to Candida albicans and Aspergillus fumigatus is mediated by antigen-specific Th1 cells. To define the role of B cells and antibodies in the generation of antifungal immune resistance, B cell-deficient (mu MT) mice were assessed f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618dd2b7ce41e39dd10efc41550f8f49
https://doi.org/10.1002/eji.200323790
https://doi.org/10.1002/eji.200323790
Autor:
Jim E. Cutler, Richard Calderone, Tresa Goins, David B. Williams, Michael Kruppa, Neeraj Chauhan, Veena Menon, Douglas W. Lowman, Dongmei Li, Praveen Singh
Publikováno v:
FEMS Yeast Research. 3:289-299
The human pathogen Candida albicans encodes at least three putative two-component histidine kinase signal transduction proteins, including Chk1p and a response regulator protein (Cssk1p). Strains deleted in CHK1 are avirulent in a murine model of hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4bb6ccd559394455bffc4bd1f6938c
https://doi.org/10.1111/j.1567-1364.2003.tb00170.x
https://doi.org/10.1111/j.1567-1364.2003.tb00170.x