Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jim C. Fong"'
Autor:
Ying-Shun Kao1, Jim C. Fong1 ffong@ym.edu.tw
Publikováno v:
Journal of Biomedical Science. Mar/Apr2004, Vol. 11 Issue 2, p206-213. 8p. 1 Black and White Photograph, 1 Chart, 6 Graphs.
Autor:
Jim C. Fong, Ying-Shiun Kao
Publikováno v:
Cellular Signalling. 20:771-778
We have shown previously that endothelin-1 (ET-1) induction of Glut1 transcription is mediated by ET-1 responsive elements on enhancer 2, via both protein kinase Cepsilon (PKCepsilon)- and p42/p44 mitogen-activated protein kinase (MAPK)-dependent pat
Autor:
Jim C. Fong, Yu-Chi Chou
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1722:148-155
We have demonstrated previously that pretreatment of GH3 pituitary cells with muscarinic agonists may induce a higher cAMP formation in response to vasoactive intestinal peptide (VIP) or forskolin. In the present study, we further examined the adenyl
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 19:205-215
Over releasing of glutamate and cellular calcium influx always results in neuronal death. In the present study, we investigated various commercial antiglaucoma drugs including timolol (0.58 microM to 58 microM), betaxolol (1.62 microM to 162 microM),
Autor:
Jim C. Fong, Shin-Pei Chai
Publikováno v:
Cellular Signalling. 15:269-277
We have demonstrated previously that 4-bromocrotonic acid (Br-C4) inhibited insulin-stimulated glucose transport by interfering with GLUT4 translocation. In the present study, we further examined the underlying mechanism involved. Since insulin-induc
Publikováno v:
Journal of Cellular Biochemistry. 85:83-91
We used nigericin, a K + /H + exchanger, to test whether glucose transport in 3T3-L1 adipocytes was modulated by changes in intracellular pH. Our results showed that nigericin increased basal but decreased insulin-stimulated glucose uptake in a time-
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1344:65-73
Two inhibitors of fatty acid oxidation, 2-bromopalmitic acid (Br-C16) and 4-bromocrotonic acid (Br-C4) were examined for their effect on lipolysis in 3T3-L1 adipocytes. Both agents inhibited in a dose-dependent manner the rate of oxidation of exogeno
Autor:
Jim C. Fong, Shin-Pei Chai
Publikováno v:
Life Sciences. 93(25-26)
We demonstrated previously that ET-1 and cAMP may synergistically induce IL-6 release from adipocytes, mainly through their strong stimulatory effect on IL-6 gene expression. In the present study, we further examined the signaling pathways that may b
Publikováno v:
Cellular Signalling. 8:179-183
Exposure of adipocytes to arachidonic acid rapidly enhanced basal 2-deoxyglucose uptake, reaching maximal effect at approximately 8 hr. Insulin-stimulated 2-deoxyglucose uptake was not altered over the experimental period. While the short-term (2-h e
Publikováno v:
International journal of obesity (2005). 37(2)
We have demonstrated previously that endothelin-1 (ET-1) may stimulate interleukin-6 (IL-6) release from 3T3-L1 adipocytes. In this study, we further examined the combined effect of ET-1 and cyclic adenosine monophosphate (cAMP) on IL-6 release.IL-6