Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jim C, Gourdon"'
Publikováno v:
Pharmacological Reports. 74:614-625
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19336e0fdd820c5ec5ab1ea36b8f49fb
https://doi.org/10.1007/s43440-022-00378-9
https://doi.org/10.1007/s43440-022-00378-9
Autor:
Min Su Kang, Adjia Hamadjida, Dominique Bédard, Stephen G. Nuara, Jim C. Gourdon, Stephen Frey, Arturo Aliaga, Karen Ross, Robert Hopewell, Hussein Bdair, Axel Mathieu, Christine Lucas Tardif, Jean-Paul Soucy, Gassan Massarweh, Pedro Rosa-Neto, Philippe Huot
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af34356d1f45332784ca1870ecc3dd7
https://doi.org/10.1007/s00210-023-02458-w
https://doi.org/10.1007/s00210-023-02458-w
Autor:
Jim C. Gourdon, Robert Hopewell, Stephen G. Nuara, Christine L. Tardif, Adjia Hamadjida, Min Su Kang, Cynthia Kwan, Dominique Bédard, Philippe Huot, Jean-Paul Soucy, Hussein Bdair, Karen Ross, Gassan Massarweh, Wen Luo, Thomas M. Durcan, Irina Shlaifer, Stephen Frey, Edward A. Fon, Pedro Rosa-Neto, Esther del Cid Pellitero
Publikováno v:
Neuroscience. 480:143-154
The common marmoset has emerged as a popular model in neuroscience research, in part due to its reproductive efficiency, genetic and neuroanatomical similarities to humans and the successful generation of transgenic lines. Stereotaxic procedures in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd3b43f96cc35bd7c209fae62f05249
https://doi.org/10.1016/j.neuroscience.2021.11.009
https://doi.org/10.1016/j.neuroscience.2021.11.009
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 394:2381-2388
PURPOSE Antagonising serotonin (5-HT) type 2A receptors (5-HT2AR) is an effective strategy to alleviate both dyskinesia and psychosis in Parkinson's disease (PD). We have recently shown that activation of metabotropic glutamate 2 receptors (mGluR2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e027fbec1f3a532623c81d5ef993dac
https://doi.org/10.1007/s00210-021-02162-7
https://doi.org/10.1007/s00210-021-02162-7
Autor:
Imane, Frouni, Cynthia, Kwan, Sébastien, Belliveau, Adjia, Hamadjida, Dominique, Bédard, Stephen G, Nuara, Jim C, Gourdon, Philippe, Huot
Publikováno v:
European journal of pharmacology. 939
In previous experiments, we have discovered that positive allosteric modulation of metabotropic glutamate 2 (mGlu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ad52f48d4ae6afbf7cb3da45f470956
https://pubmed.ncbi.nlm.nih.gov/36502960
https://pubmed.ncbi.nlm.nih.gov/36502960
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 394:1685-1692
Parkinson’s disease (PD) psychosis afflicts over half of patients and poses a significant burden on quality of life. The aetiology of PD psychosis is multifactorial and likely arises from the complex interaction between dopamine replacement therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f2aa35c1eea3939618146b628309328
https://doi.org/10.1007/s00210-021-02090-6
https://doi.org/10.1007/s00210-021-02090-6
Autor:
Adjia Hamadjida, Imane Frouni, Sébastien Belliveau, Woojin Kang, Dominique Bédard, Jim C. Gourdon, Stephen G. Nuara, Cynthia Kwan, Philippe Huot
Publikováno v:
Journal of Neural Transmission. 128:73-81
Advanced Parkinson’s disease (PD) is often complicated by the occurrence of dyskinesia, motor fluctuations and psychosis. To this day, few treatment options are available for each of these phenomena, and they are at times not effective or elicit ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce71a226053805a7d777dc6b0d9db1b
https://doi.org/10.1007/s00702-020-02287-8
https://doi.org/10.1007/s00702-020-02287-8
Autor:
Dominique Bédard, Imane Frouni, Adjia Hamadjida, Jim C. Gourdon, Cynthia Kwan, Philippe Huot, Stephen G. Nuara
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 393:2157-2164
Whereas monoamine oxidase (MAO) type B inhibitors are used as adjunct to L-3,4-dihydroxyphenylalanine (L-DOPA) in the treatment of Parkinson’s disease (PD), the enzyme MAO type A (MAO-A) also participates in the metabolism of dopamine in the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10c9c70e9f7612574e36af19bb538557
https://doi.org/10.1007/s00210-020-01933-y
https://doi.org/10.1007/s00210-020-01933-y
Autor:
Adjia Hamadjida, Jim C. Gourdon, Stephen G. Nuara, Cynthia Kwan, Imane Frouni, Philippe Huot, Dominique Bédard
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 393:2139-2144
Monoamine oxidase (MAO) type B (MAO-B) inhibition was shown to confer anti-parkinsonian benefit as monotherapy and adjunct to l-3,4-dihydroxyphenylalanine (l-DOPA) in clinical trials. Here, we explore the anti-parkinsonian effect of MAO type A (MAO-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::366f59a40b171c14cb96004b153ba0ea
https://doi.org/10.1007/s00210-020-01927-w
https://doi.org/10.1007/s00210-020-01927-w
Publikováno v:
Journal of Neural Transmission. 127:1013-1021
We have recently shown that activation of metabotropic glutamate 2 (mGlu2) receptors through positive allosteric modulation and orthosteric stimulation is a novel approach to reduce L-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia and dopamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8482fc85c473b45aa96cee4e79dc1b3
https://doi.org/10.1007/s00702-020-02196-w
https://doi.org/10.1007/s00702-020-02196-w