Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jim Boulter"'
Autor:
Julian Taranda, Stéphane F Maison, Jimena A Ballestero, Eleonora Katz, Jessica Savino, Douglas E Vetter, Jim Boulter, M Charles Liberman, Paul A Fuchs, A Belén Elgoyhen
Publikováno v:
PLoS Biology, Vol 7, Iss 1, p e18 (2009)
The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is wha
Externí odkaz:
https://doaj.org/article/fe6e8caadb304db3972a5af73403bdc9
Autor:
Christine Lavoie, Jade Degrandmaison, Véronique Blais, Jim Boulter, Jean-Luc Parent, Samuel Génier, Khaled Abdallah, Louis Gendron, Catherine M. Cahill, Francis Bergeron, Marie-Pier Lalumière
Publikováno v:
Proc Natl Acad Sci U S A
With over 30% of current medications targeting this family of proteins, G-protein–coupled receptors (GPCRs) remain invaluable therapeutic targets. However, due to their unique physicochemical properties, their low abundance, and the lack of highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e552663e1b33fafd3197dc42e973a4a1
https://doi.org/10.1073/pnas.1917906117
https://doi.org/10.1073/pnas.1917906117
Autor:
Maria Marcela Lipovsek, Celina Mojica, Sarah Silverstein, Sakura Nakauchi, Jesse D. Cushman, Andrew M. Poulos, James Tirtorahardjo, Ana Belén Elgoyhen, Michael S. Fanselow, Katumi Sumikawa, Jim Boulter, Shahrdad Lotfipour
The absence of α2* nicotinic acetylcholine receptors (nAChRs) in oriens lacunosum moleculare (OLM) GABAergic interneurons ablate the facilitation of nicotine-induced hippocampal CA1 long-term potentiation and impair memory. The current study delinea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3a8814750030e2676a4c1e9cc75348
https://europepmc.org/articles/PMC5435881/
https://europepmc.org/articles/PMC5435881/
Publikováno v:
The Journal of Neuroscience. 29:3014-3018
In humans, tobacco withdrawal produces symptoms that contribute to the difficulty associated with smoking cessation. Nicotine withdrawal symptoms can also be observed in rodents. A major standing question is which nicotinic receptor subtypes and whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34943e788fb1eb188377d5655130c4bd
https://doi.org/10.1523/jneurosci.4934-08.2009
https://doi.org/10.1523/jneurosci.4934-08.2009
Publikováno v:
European Journal of Neuroscience. 25:2666-2681
Hippocampal CA1 pyramidal cells receive two major excitatory synaptic inputs via the Schaffer collateral (SC) and temporoammonic (TA) pathways. Nicotine promotes induction of long-term potentiation (LTP) in the SC path; however, it is not known wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c3a6e671c73653d8c40bdffebc3fe43
https://doi.org/10.1111/j.1460-9568.2007.05513.x
https://doi.org/10.1111/j.1460-9568.2007.05513.x
Publikováno v:
Proceedings of the National Academy of Sciences. 103:19152-19157
Selected mutations in the human α4 or β2 neuronal nicotinic acetylcholine receptor subunit genes cosegregate with a partial epilepsy syndrome known as autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). To examine possible mechanisms under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5853ff4c0850d0ad923546324ad4ff
https://doi.org/10.1073/pnas.0608215103
https://doi.org/10.1073/pnas.0608215103
Autor:
Weihong Ge, Ena Ladi, Jim Boulter, James T. Nichols, Chris Kintner, Yi E. Sun, Alison Miyamoto, Gerry Weinmaster, Liang-Tung Yang, Christine Yao
Publikováno v:
The Journal of Cell Biology
Mutations in the DSL (Delta, Serrate, Lag2) Notch (N) ligand Delta-like (Dll) 3 cause skeletal abnormalities in spondylocostal dysostosis, which is consistent with a critical role for N signaling during somitogenesis. Understanding how Dll3 functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858ab9f174aa841d3e189bb4907c6d4e
https://doi.org/10.1083/jcb.200503113
https://doi.org/10.1083/jcb.200503113
Autor:
Allan C. Collins, Sharon R. Grady, Michael J. Marks, Roberta Allen, W. R. Allen, Jim Boulter, J. Michael McIntosh, Christopher M. Butt, Jerry A. Stitzel, Theresa Tritto, T. K. Booker, Stephen F. Heinemann, Changhai Cui, Outi Salminen, Paul Whiteaker
Publikováno v:
The Journal of Neuroscience. 23:11045-11053
Nigrostriatal dopaminergic neurons express many nicotinic acetylcholine receptor (nAChR) subunits capable of forming multiple nAChR subtypes. These subtypes are expressed differentially along the neuron and presumably mediate diverse responses. beta3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df4319090e2d498a5ff91b349d1fb24
https://doi.org/10.1523/jneurosci.23-35-11045.2003
https://doi.org/10.1523/jneurosci.23-35-11045.2003
Publikováno v:
The Journal of Comparative Neurology. 467:496-508
Male zebra finches develop a robust neural song system that supports singing, but females have a minimal song circuit and do not sing. Estrogens masculinize the song circuit and are especially potent during the first 3 weeks of posthatch development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aeaf0122cdb59f74915caeb86abdc2
https://doi.org/10.1002/cne.10936
https://doi.org/10.1002/cne.10936
Publikováno v:
Journal of Biological Chemistry. 276:38727-38737
Ca(2+) enters pituitary and pancreatic neuroendocrine cells through dihydropyridine-sensitive channels triggering hormone release. Inhibitory metabotropic receptors reduce Ca(2+) entry through activation of pertussis toxin-sensitive G proteins leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1786b9a2da7feefe20c1c9f47ba2ed5
https://doi.org/10.1074/jbc.m103724200
https://doi.org/10.1074/jbc.m103724200