Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Jilong Yang"'
Autor:
Peipei Xing, Haotian Liu, Wanyi Xiao, Gengpu Zhang, Chao Zhang, Zhichao Liao, Ting Li, Jilong Yang
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Through transcriptome sequencing, we previously identified a new osteosarcoma-specific, frequent fusion gene, LRP1–SNRNP25, and found that it played an important role in tumor cell invasion and migration. However, the specific mechanism re
Externí odkaz:
https://doaj.org/article/62a3a795f33f400eab21be4bff4d8da6
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 2, Pp 125-131 (2024)
Externí odkaz:
https://doaj.org/article/fe790c087ad249ffa19ef5c897a66ceb
Autor:
Zhichao Liao, Jianjin Teng, Tao Li, Haotian Liu, Ting Li, Chao Zhang, Ruwei Xing, Sheng Teng, Yun Yang, Jun Zhao, Wanyi Xiao, Gengpu Zhang, Mulin Jun Li, Weitao Yao, Jilong Yang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSarcoma is a highly heterogeneous malignancy with a poor prognosis. Although chemotherapy and targeted therapy have improved the prognosis to some extent, the efficacy remains unsatisfactory in some patients. The efficacy and safety of immu
Externí odkaz:
https://doaj.org/article/9a44e26d31ed4aea83d878e10b23e41a
Autor:
Zhao Wang, Menghan Luo, Qian Liang, Ke Zhao, Yuelin Hu, Wei Wang, Xiangling Feng, Bolang Hu, Jianjin Teng, Tianyi You, Ran Li, Zhengkai Bao, Wenhao Pan, Tielong Yang, Chao Zhang, Ting Li, Xiaobao Dong, Xianfu Yi, Ben Liu, Li Zhao, Miaoxin Li, Kexin Chen, Weihong Song, Jilong Yang, Mulin Jun Li
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-32 (2023)
Abstract Background The high mutation rate throughout the entire melanoma genome presents a major challenge in stratifying true driver events from the background mutations. Numerous recurrent non-coding alterations, such as those in enhancers, can sh
Externí odkaz:
https://doaj.org/article/ea2c5d7f313e4e34877e64882a16ffd9
Autor:
Gengpu Zhang, Shengnan Li, Wanyi Xiao, Chao Zhang, Ting Li, Zhichao Liao, Haotian Liu, Ruwei Xing, Wei Yao, Jilong Yang
Publikováno v:
Cancers, Vol 16, Iss 5, p 908 (2024)
Immunotherapy is an essential therapy for individuals with advanced melanoma. However, not all patients respond to such treatment due to individual differences. We conducted a multidimensional analysis using transcriptome data from our center, as wel
Externí odkaz:
https://doaj.org/article/9f7ea4424ae84dc7b82ed5b2a567ecd1
Autor:
Chao Zhang, Hongru Shen, Tielong Yang, Ting Li, Xinyue Liu, Jin Wang, Zhichao Liao, Junqiang Wei, Jia Lu, Haotian Liu, Lijie Xiang, Yichen Yang, Meng Yang, Duan Wang, Yang Li, Ruwei Xing, Sheng Teng, Jun Zhao, Yun Yang, Gang Zhao, Kexin Chen, Xiangchun Li, Jilong Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Studying the cell composition of acral melanoma at the single-cell level could provide some clues about its poor response to immunotherapy. Here, the authors analyse acral and cutaneous melanoma patient samples using single-cell RNA-sequencing, and r
Externí odkaz:
https://doaj.org/article/669ad832d29f41e1866555df7dad9271
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeTo establish and validate a machine learning based radiomics model for detection of perineural invasion (PNI) in gastric cancer (GC).MethodsThis retrospective study included a total of 955 patients with GC selected from two centers; they were
Externí odkaz:
https://doaj.org/article/d84dc2125b9c4646a1e83d233e54ac79
Autor:
Hongru Shen, Jilei Liu, Jiani Hu, Xilin Shen, Chao Zhang, Dan Wu, Mengyao Feng, Meng Yang, Yang Li, Yichen Yang, Wei Wang, Qiang Zhang, Jilong Yang, Kexin Chen, Xiangchun Li
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106536- (2023)
Summary: Exponential accumulation of single-cell transcriptomes poses great challenge for efficient assimilation. Here, we present an approach entitled generative pretraining from transcriptomes (tGPT) for learning feature representation of transcrip
Externí odkaz:
https://doaj.org/article/e0dcbba863d546048eee88d43a6990d4
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 10, Pp 1496-1502 (2022)
Externí odkaz:
https://doaj.org/article/2628b5ad7c334906a4c5c6a2342af4ec
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 8, Pp 1211-1223 (2022)
Objective: The BRAF inhibitor, vemurafenib, has been widely used in the treatment of patients with melanoma-bearing BRAFV600E mutations. While the initial response to vemurafenib is usually excellent, the majority of patients eventually develop resis
Externí odkaz:
https://doaj.org/article/a4c7194c32844833b7fac0b3b5911027