Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jilong Qin"'
Publikováno v:
Chinese Journal of Lung Cancer, Vol 26, Iss 9, Pp 650-658 (2023)
Background and objective The biological and molecular characteristics of spread through air spaces (STAS), a newly recognized invasive mode of lung cancer, remain controversial. The aim of this study was to investigate the clinicopathological feature
Externí odkaz:
https://doaj.org/article/f69e2b119b14448dbbd208871e7a22f5
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010996 (2023)
Escherichia coli K-12 is a model organism for bacteriology and has served as a workhorse for molecular biology and biochemistry for over a century since its first isolation in 1922. However, Escherichia coli K-12 strains are phenotypically devoid of
Externí odkaz:
https://doaj.org/article/43609157a46c48a0be79f9151956b4b0
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Bacterial capsules provide protection against environmental challenges and host immunity. Historically, Escherichia coli K serotyping scheme, which relies on the hypervariable capsules, has identified around 80 K forms that fall into four di
Externí odkaz:
https://doaj.org/article/92fd7bb988294591a5539955cf2f8697
Autor:
Audrey R. N. Ndukwe, Jilong Qin, Sandra Wiedbrauk, Nathan R. B. Boase, Kathryn E. Fairfull-Smith, Makrina Totsika
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1706 (2023)
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a global health concern. The propensity of MRSA to form biofilms is a significant contributor to its pathogenicity. Strategies to treat biofilms often involve small molecules
Externí odkaz:
https://doaj.org/article/879040d3aabe4b4d834b6bb639741ced
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract The study of clinically relevant bacterial pathogens relies on molecular and genetic approaches. However, the generally low transformation frequency among natural isolates poses technical hurdles to widely applying common methods in molecula
Externí odkaz:
https://doaj.org/article/5838b3db970b4442be2060c4a6cc7c33
Publikováno v:
Antibiotics, Vol 12, Iss 10, p 1479 (2023)
Urinary tract infections (UTIs) are the second most common bacterial infection with high recurrence rates and can involve biofilm formation on patient catheters. Biofilms are inherently tolerant to antimicrobials, making them difficult to eradicate.
Externí odkaz:
https://doaj.org/article/da09728af84f4a31bf10fe61af743f6e
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4532-4541 (2022)
The binding of the type 1 fimbrial adhesin FimH to mannosylated receptors is allosterically regulated to enhance the fitness of uropathogenic Escherichia coli (UPEC) during urinary tract infection (UTI). Mutations in the two FimH domains (pilin and l
Externí odkaz:
https://doaj.org/article/7a1990c63ae142079b7504dc7db0bedb
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Shigella IcsA is a versatile surface virulence factor required for early and late pathogenesis stages extracellularly and intracellularly. Despite IcsA serving as a model Type V secretion system (T5SS) autotransporter to study host-pathogen
Externí odkaz:
https://doaj.org/article/af27a945fe794d46a6ae6288e507c5cd
Autor:
Carola Venturini, Bethany Bowring, Sally R. Partridge, Nouri L. Ben Zakour, Alicia Fajardo-Lubian, Ariana Lopez Ayala, Jilong Qin, Makrina Totsika, Gaby van Galen, Jacqueline Norris, Jonathan Iredell
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT The global epidemiology of multidrug resistant Klebsiella pneumoniae, a serious threat to both animal and human health, is dominated by the spread of pathogenic clones, each separately evolving via acquisition of transferable antibiotic resi
Externí odkaz:
https://doaj.org/article/e5ca775725a04b35af5f4367ef588f6b
Autor:
Yaoqin Hong, Jilong Qin, Anthony D. Verderosa, Sophia Hawas, Bing Zhang, Mark A. T. Blaskovich, John E. Cronan, Makrina Totsika
Publikováno v:
mSphere, Vol 7, Iss 3 (2022)
ABSTRACT Antibiotic resistance is one of the most prominent threats to modern medicine. In the latest World Health Organization list of bacterial pathogens that urgently require new antibiotics, 9 out of 12 are Gram-negative, with four being of “cr
Externí odkaz:
https://doaj.org/article/b9f5f0e1e2d3478f8b00822452660aa7