Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jillian S. Shapiro"'
Autor:
David H. Sachs, Lauren C. Aguado, Sara Cherry, Benjamin R. tenOever, Leah R. Sabin, Ari Yasunaga, Jaehee V. Shim, Sonja Schmid, Jillian S. Shapiro
Publikováno v:
Proceedings of the National Academy of Sciences. 111:7108-7113
Utilization of antiviral small interfering RNAs is thought to be largely restricted to plants, nematodes, and arthropods. In an effort to determine whether a physiological interplay exists between the host small RNA machinery and the cellular respons
Autor:
Kemin Xu, Courtney Finch, Jillian S. Shapiro, Ryan A. Langlois, Matthew Angel, Benjamin R. tenOever, Randy A. Albrecht, Troy C. Sutton, Ana S. Gonzalez-Reiche, Brian Kimble, Daniel R. Perez, Adolfo García-Sastre, Mark A. Chua
Publikováno v:
Nature biotechnology
Nature Biotechnology
Nature Biotechnology
Recent gain-of-function studies in influenza A virus H5N1 strains revealed that as few as three amino-acid changes in the hemagglutinin protein confer the capacity for viral transmission between ferrets1, 2. As transmission between ferrets is conside
Autor:
Jillian S. Shapiro
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 4:463-471
MicoRNAs (miRNAs) are small noncoding RNAs that associate with Argonaute (AGO) family member proteins to mediate silencing of host mRNA transcripts. A number of DNA viruses and a single retrovirus exploit this pathway to generate their own miRNAs in
Autor:
Leah R. Sabin, Sara Cherry, Jillian S. Shapiro, Bernard Moss, Benjamin R. tenOever, Ismarc Reyes, Simone Backes, Alissa M. Pham
Publikováno v:
Cell Host & Microbe. 12(2):200-210
SUMMARY The life cycle of several viruses involves host or virally encoded small noncoding RNAs, which play important roles in posttranscriptional regulation. Small noncoding RNAs include microRNAs (miRNAs), which modulate the transcriptome, and smal
Publikováno v:
Molecular Therapy. 20:367-375
The discovery of microRNAs (miRNAs) revealed an unappreciated level of post-transcriptional control used by the cell to maintain optimal protein levels. This process has represented an attractive strategy for therapeutics that is currently limited by
Publikováno v:
RNA. 16:2068-2074
Cellular utilization of RNA interference (RNAi) as a mechanism to combat virus infection is thought to be restricted to plants and invertebrates. In vertebrates, antiviral defenses are largely dependent on interferons (IFNs), with the use of small RN
Autor:
Jillian S, Shapiro
Publikováno v:
Wiley interdisciplinary reviews. RNA. 4(4)
MicoRNAs (miRNAs) are small noncoding RNAs that associate with Argonaute (AGO) family member proteins to mediate silencing of host mRNA transcripts. A number of DNA viruses and a single retrovirus exploit this pathway to generate their own miRNAs in
Publikováno v:
RNA (New York, N.Y.). 18(7)
microRNAs (miRNAs) represent a class of noncoding RNAs that fine-tune gene expression through post-transcriptional silencing. While miRNA biogenesis occurs in a stepwise fashion, initiated by the nuclear microprocessor, rare noncanonical miRNAs have