Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jillian R. Hufgard"'
Autor:
Samantha L. Regan, Emily M. Pitzer, Jillian R. Hufgard, Chiho Sugimoto, Michael T. Williams, Charles V. Vorhees
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105456- (2021)
Latrophilins (LPHNs) are adhesion G protein-coupled receptors with three isoforms but only LPHN3 is brain specific (caudate, prefrontal cortex, dentate, amygdala, and cerebellum). Variants of LPHN3 are associated with ADHD. Null mutations of Lphn3 in
Externí odkaz:
https://doaj.org/article/02d801f1a8994218b16fd0930b543a3e
Autor:
Samantha L. Regan, Jillian R. Hufgard, Emily M. Pitzer, Chiho Sugimoto, Yueh-Chiang Hu, Michael T. Williams, Charles V. Vorhees
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104494- (2019)
Attention deficit hyperactivity disorder is a pervasive developmental disorder characterized by inattention, impulsivity, and hyperactivity and is 75–90% heritable. Latrophilin-3 (LPHN3; or ADGRL(3)) is associated with a subtype of ADHD, but how it
Externí odkaz:
https://doaj.org/article/c41c9e4579ce4005be30cbffbec39db8
Autor:
Michael T. Williams, Ann M. Hemmerle, Kim B. Seroogy, Tara L Kyser, Rebecca A. Bailey, Charles V. Vorhees, Arnold Gutierrez, Jillian R. Hufgard
Publikováno v:
Neurotoxicity Research. 35:606-620
Manganese (Mn) is an essential nutrient especially during development, but Mn overexposure (MnOE) produces long-term cognitive deficits. Evidence of long-term changes in dopamine in the neostriatum was found in rats from developmental MnOE previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321f6b3756aa4ebd345ee6c2510bb145
https://doi.org/10.1007/s12640-018-9992-1
https://doi.org/10.1007/s12640-018-9992-1
Autor:
Charles V. Vorhees, Sheryl E. Koch, Jenna L.N. Sprowles, Xiang Zhang, Qin Wang, Michael T. Williams, Alvaro Puga, Jacek Biesiada, Min Jiang, Emily M. Pitzer, Jillian R. Hufgard, Jack Rubinstein
Publikováno v:
Journal of Applied Toxicology. 39:603-621
Polychlorinated biphenyls (PCBs) are toxic environmental pollutants. Humans are exposed to PCB mixtures via contaminated food or water. PCB exposure causes adverse effects in adults and after exposure in utero. PCB toxicity depends on the congener mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18a9721d73c61b54f2c46467796c855b
https://doi.org/10.1002/jat.3751
https://doi.org/10.1002/jat.3751
Autor:
Chiho Sugimoto, Charles V. Vorhees, Michael T. Williams, Jillian R. Hufgard, Samantha L. Regan, Emily M. Pitzer
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 158, Iss, Pp 105456-(2021)
Neurobiology of Disease, Vol 158, Iss, Pp 105456-(2021)
Latrophilins (LPHNs) are adhesion G protein-coupled receptors with three isoforms but only LPHN3 is brain specific (caudate, prefrontal cortex, dentate, amygdala, and cerebellum). Variants of LPHN3 are associated with ADHD. Null mutations of Lphn3 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a202b04bac7413664ba85c3a579e1c1
https://doi.org/10.1016/j.nbd.2021.105456
https://doi.org/10.1016/j.nbd.2021.105456
Autor:
Charles V. Vorhees, Michael T. Williams, Jillian R. Hufgard, Filipa M. Ferreira, Tracy M. Reed-Kessler, Mary E. Wright, Matthew R. Skelton, Ronald S. Duman, Olivera Grubisha, Kurt Rasmussen, Helen E. Sanger
Publikováno v:
Psychopharmacology. 234:1803-1813
Rationale Major depressive disorder is a leading cause of suicide and disability. Despite this, current antidepressants provide insufficient efficacy in more than 60% of patients. Most current antidepressants are presynaptic reuptake inhibitors; post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6f937327161db63f3d829e204b4ff9
https://doi.org/10.1007/s00213-017-4587-8
https://doi.org/10.1007/s00213-017-4587-8
Autor:
Chiho Sugimoto, Emily M. Pitzer, Samantha L. Regan, Jillian R. Hufgard, Charles V. Vorhees, Yueh-Chiang Hu, Michael T. Williams
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 130, Iss, Pp 104494-(2019)
Neurobiology of Disease, Vol 130, Iss, Pp 104494-(2019)
Attention deficit hyperactivity disorder is a pervasive developmental disorder characterized by inattention, impulsivity, and hyperactivity and is 75–90% heritable. Latrophilin-3 (LPHN3; or ADGRL(3)) is associated with a subtype of ADHD, but how it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62f49415b7c252f2e936d05652d7dbf
https://pubmed.ncbi.nlm.nih.gov/31176715
https://pubmed.ncbi.nlm.nih.gov/31176715
Autor:
Arnold Gutierrez, Jillian R. Hufgard, Robyn M. Amos-Kroohs, Laurie L. Davenport, Michael T. Williams, Charles V. Vorhees
Publikováno v:
Neurotoxicol Teratol
Manganese (Mn) is an essential element but neurotoxic at higher exposures, however, Mn exposure seldom occurs in isolation. It often co-occurs in populations with inadequate dietary iron (Fe) and limited resources that result in stress. Subclinical F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ef3fd611a5d2054c2a28cdbc347313
https://doi.org/10.1016/j.ntt.2016.06.004
https://doi.org/10.1016/j.ntt.2016.06.004
Autor:
Jillian R, Hufgard, Jenna L N, Sprowles, Emily M, Pitzer, Sheryl E, Koch, Min, Jiang, Qin, Wang, Xiang, Zhang, Jacek, Biesiada, Jack, Rubinstein, Alvaro, Puga, Michael T, Williams, Charles V, Vorhees
Publikováno v:
Journal of applied toxicology : JAT. 39(4)
Polychlorinated biphenyls (PCBs) are toxic environmental pollutants. Humans are exposed to PCB mixtures via contaminated food or water. PCB exposure causes adverse effects in adults and after exposure in utero. PCB toxicity depends on the congener mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1df24cd68f0eab382c5d1f377fcca51
https://pubmed.ncbi.nlm.nih.gov/30561030
https://pubmed.ncbi.nlm.nih.gov/30561030
Publikováno v:
Genes, Brain and Behavior.
Phosphodiesterase-1b (Pde1b) is highly expressed in striatum, dentate gyrus, CA3, and substantia nigra. In a new Floxed Pde1b x CreCMV global knock-out (KO) mouse model we show an immobility resistance phenotype that recapitulates that found in const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5be55f8ee369ed4708115913d288bcab
https://doi.org/10.1111/gbb.12391
https://doi.org/10.1111/gbb.12391