Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jillian McEwan"'
Autor:
Jillian McEwan, Reza J. Rasoulpour, B. Bhaskar Gollapudi, Amanda J. Wood, David R. Geter, Audrey Vardy, Matthew J. LeBaron, Jennifer A. Murray, Claire Terry, Johnson Thomas, Cliff Elcombe, Richard Billington, H. Lynn Kan
Publikováno v:
Toxicology and Applied Pharmacology. 270:164-173
Registration of new plant protection products (e.g., herbicide, insecticide, or fungicide) requires comprehensive mammalian toxicity evaluation including carcinogenicity studies in two species. The outcome of the carcinogenicity testing has a signifi
Autor:
Anja Rode, Vincent Beuger, Yury Kapelyukh, Jillian McEwan, Nico Scheer, C. Roland Wolf, Lesley A. Stanley
Publikováno v:
Molecular pharmacology. 81(1)
The highly polymorphic human cytochrome P450 2D6 enzyme is involved in the metabolism of up to 25% of all marketed drugs and accounts for significant individual differences in response to CYP2D6 substrates. Because of the differences in the multiplic