Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jillian L. Perry"'
Publikováno v:
ACS Omega, Vol 4, Iss 3, Pp 5547-5555 (2019)
Externí odkaz:
https://doaj.org/article/e4c3813dd8354b7486b53790dae5c0fa
Autor:
J. Christopher Luft, Nisitha Sengottuvel, Joseph M. DeSimone, Shaomin Tian, Emily B. Harrison, Balachandra K. Gorentla, Jenny P.-Y. Ting, Chintan H. Kapadia, Ning Cheng, Chad V. Pecot, Jillian L. Perry
Publikováno v:
ACS Nano
CpG oligodeoxynucleotides are potent toll-like receptor (TLR) 9 agonists and have shown promise as anticancer agents in preclinical studies and clinical trials. Binding of CpG to TLR9 initiates a cascade of innate and adaptive immune responses, begin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18344900f19ee8fdf7bdb2975763fcef
https://doi.org/10.1021/acsnano.0c02207
https://doi.org/10.1021/acsnano.0c02207
Publikováno v:
ACS Omega
ACS Omega, Vol 4, Iss 3, Pp 5547-5555 (2019)
ACS Omega, Vol 4, Iss 3, Pp 5547-5555 (2019)
Multiple studies have been published emphasizing the significant role of nanoparticle (NP) carriers in antigenic peptide-based subunit vaccines for the induction of potent humoral and cellular responses. Various design parameters of nanoparticle subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04732783c7d0c61561e9d56daafe9cf4
http://europepmc.org/articles/PMC6450662
http://europepmc.org/articles/PMC6450662
Publikováno v:
Journal of Controlled Release. 284:122-132
Microneedle patches, arrays of micron-scale projections that penetrate skin in a minimally invasive manner, are a promising tool for transdermally delivering therapeutic proteins. However, current microneedle fabrication techniques are limited in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b4f8e0e35181901aa90f6ec8861c80
https://doi.org/10.1016/j.jconrel.2018.05.042
https://doi.org/10.1016/j.jconrel.2018.05.042
Autor:
Shaomin Tian, J. Christopher Luft, Chintan H. Kapadia, Jillian L. Perry, Joseph M. DeSimone, David Sailer
Publikováno v:
Journal of Controlled Release. 269:393-404
Tumor-specific CD8+ cytotoxic T lymphocytes (CTLs) play a critical role in an anti-tumor immune response. However, vaccination intended to elicit a potent CD8+ T cell responses employing tumor-associated peptide antigens, are typically ineffective du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166daccb8afec2b57f1339984100bcfc
https://doi.org/10.1016/j.jconrel.2017.11.020
https://doi.org/10.1016/j.jconrel.2017.11.020
Autor:
Rihe Liu, Joseph M. DeSimone, J. Christopher Luft, Dong Wook Kim, Kevin G. Reuter, Jillian L. Perry
Publikováno v:
Nano Letters. 15:6371-6378
In this Letter, we varied targeting ligand density of an EGFR binding affibody on the surface of two different hydrogel PRINT nanoparticles (80 nm × 320 and 55 nm × 60 nm) and monitored effects on target-cell association, off-target phagocytic upta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca704a78520069bce0801c600cb3e57
https://doi.org/10.1021/acs.nanolett.5b01362
https://doi.org/10.1021/acs.nanolett.5b01362
Autor:
Jillian L. Perry, Chad V. Pecot, William C. Zamboni, Kevin G. Reuter, J. Christopher Luft, Joseph M. DeSimone
As the enhanced permeation and retention (EPR) effect continues to be a controversial topic in nanomedicine, we sought to examine EPR as a function of nanoparticle size, tumor model, and tumor location, while also evaluating tumors for EPR mediating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e151d159ed0a88caf5a496b3fdc30e5
Autor:
Charles M. Perou, William C. Zamboni, Mary E. Napier, Jillian L. Perry, Allison M. Deal, Allison N. Schorzman, James C. Luft, Joseph M. DeSimone, Amanda W. Keeler, Charles J. Bowerman, Candice A. Sherwood, Kevin S. Chu, David B. Darr, Norman E. Sharpless, James D. Byrne
Publikováno v:
Nano letters. 17(1)
Novel treatment strategies, including nanomedicine, are needed for improving management of triple-negative breast cancer. Patients with triple-negative breast cancer, when considered as a group, have a worse outcome after chemotherapy than patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fc98efbedfc1278a27e7b51b86fbc1
https://pubmed.ncbi.nlm.nih.gov/27966988
https://pubmed.ncbi.nlm.nih.gov/27966988
Autor:
J. Chris Luft, James E. Bear, Marc P. Kai, Kevin P. Herlihy, Kevin G. Reuter, Joseph M. DeSimone, Jillian L. Perry, Mary E. Napier, Stephen W. Jones
Publikováno v:
Nano Letters. 12:5304-5310
In this account, we varied PEGylation density on the surface of hydrogel PRINT nanoparticles and systematically observed the effects on protein adsorption, macrophage uptake, and circulation time. Interestingly, the density of PEGylation necessary to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9a77463d0599c29c69f4fc4b55b497
https://doi.org/10.1021/nl302638g
https://doi.org/10.1021/nl302638g
Publikováno v:
Langmuir. 28:8773-8781
We describe the fabrication of filamentous hydrogel nanoparticles using a unique soft lithography based particle molding process referred to as PRINT (Particle Replication in Non-wetting Templates). The nanoparticles possess a constant width of 80 nm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0505e4157350c5af95be974bf862082a
https://doi.org/10.1021/la301279v
https://doi.org/10.1021/la301279v