Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jillian L. Ellis"'
Autor:
Sophie Karolczak, Ashish R. Deshwar, Evangelina Aristegui, Binita M. Kamath, Michael W. Lawlor, Gaia Andreoletti, Jonathan Volpatti, Jillian L. Ellis, Chunyue Yin, James J. Dowling
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
X-linked myotubular myopathy (XLMTM) is a fatal congenital disorder caused by mutations in the MTM1 gene. Currently, there are no approved treatments, although AAV8-mediated gene transfer therapy has shown promise in animal models and preliminarily i
Externí odkaz:
https://doaj.org/article/abfd1acb3f994c4088ffb37901d8f229
Autor:
Jillian L. Ellis, Kimberley J. Evason, Changwen Zhang, Makenzie N. Fourman, Jiandong Liu, Nikolay Ninov, Marion Delous, Benoit Vanhollebeke, Ian Fiddes, Jessica P. Otis, Yariv Houvras, Steven A. Farber, Xiaolei Xu, Xueying Lin, Didier Y. R. Stainier, Chunyue Yin
Publikováno v:
Hepatology Communications, Vol 6, Iss 11, Pp 3083-3097 (2022)
Abstract Hepatic cysts are fluid‐filled lesions in the liver that are estimated to occur in 5% of the population. They may cause hepatomegaly and abdominal pain. Progression to secondary fibrosis, cirrhosis, or cholangiocarcinoma can lead to morbid
Externí odkaz:
https://doaj.org/article/56e077b691b242e1a3b5f2383c323660
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 11, Pp 1383-1396 (2016)
Alcoholic liver disease (ALD) results from alcohol overconsumption and is among the leading causes of liver-related morbidity and mortality worldwide. Elevated expression of vascular endothelial growth factor (VEGF) and its receptors has been observe
Externí odkaz:
https://doaj.org/article/a2243b5f31114527aad48aecaa75cc31
Autor:
Jillian L. Ellis, Kimberley J. Evason, Changwen Zhang, Makenzie N. Fourman, Jiandong Liu, Nikolay Ninov, Marion Delous, Benoit Vanhollebeke, Ian Fiddes, Jessica P. Otis, Yariv Houvras, Steven A. Farber, Xiaolei Xu, Xueying Lin, Didier Y.R. Stainier, Chunyue Yin
Hepatic cysts are fluid-filled lesions in the liver that are estimated to occur in 5% of the population. They may cause hepatomegaly and abdominal pain. Progression to secondary fibrosis, cirrhosis, or cholangiocarcinoma can lead to morbidity and mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dbdba3f64506344f3856007eaccdb80
https://doi.org/10.1101/2022.02.24.481764
https://doi.org/10.1101/2022.02.24.481764
Autor:
Changwen Zhang, Kuan-lin Huang, Jaime Chu, Isabel Sakarin, Scott L. Friedman, Carlos Villacorta-Martin, Jillian L. Ellis, Joshua Morrison, Young-Min Lee, Augusto Villanueva, M. Isabel Fiel, Chunyue Yin, Maria Ybanez, Kathryn Bambino, Takuya F. Sakaguchi, Charles DeRossi
Publikováno v:
Hepatology. 70:2107-2122
The growing burden of liver fibrosis and lack of effective antifibrotic therapies highlight the need for identification of pathways and complementary model systems of hepatic fibrosis. A rare, monogenic disorder in which children with mutations in ma
Autor:
Daniel Leino, Alexander Miethke, Chunyue Yin, Jillian L. Ellis, John D. Schuetz, C. Alexander Valencia, Kevin E. Bove, Erin G. Schuetz
Publikováno v:
Hepatology. 67:1531-1545
Bile salt export pump (BSEP) adenosine triphosphate-binding cassette B11 (ABCB11) is a liver-specific ABC transporter that mediates canalicular bile salt excretion from hepatocytes. Human mutations in ABCB11 cause progressive familial intrahepatic ch
Autor:
Immaculeta Osuji, Ammar Husami, Kejian Zhang, Duc-Hung Pham, Liva Pfuhler, Kimberley J. Evason, Nelson Matuschek, Mary P. Mullen, Sami Wali, Laura N. Bull, Ramesh Kudira, Jillian L. Ellis, C. Alexander Valencia, Lingfen Xu, Tiffany Shi, Chunyue Yin, Alexander Miethke, Sujit K. Mohanty
Publikováno v:
Gastroenterology
Background & Aims The etiology of cholestasis remains unknown in many children. We surveyed the genome of children with chronic cholestasis for variants in genes not previously associated with liver disease and validated their biological relevance in
Autor:
Jillian L. Ellis, Chunyue Yin, Alexander Miethke, Sami Wali, Mary Mulen, Sujit K. Mohanty, Lingfen Xu, Tiffany Shi, Duc-Hung Pham, Alexander Valencia
Publikováno v:
Journal of Hepatology. 70:e82-e83
Autor:
Chunyue Yin, Jillian L. Ellis
Publikováno v:
Journal of Visualized Experiments.
Alcoholic Liver Disease (ALD) refers to damage to the liver due to acute or chronic alcohol abuse. It is among the leading causes of alcohol-related morbidity and mortality and affects more than 2 million people in the United States. A better underst
Publikováno v:
Synthetic Communications. 43:1676-1682
Mitsunobu coupling of 3-hydroxymethylbenzofurans with o-iodophenols affords 3-(2-iodophenoxy)methylbenzofurans which under go a useful 6-endo Heck cyclization under Jeffery conditions to afford pterocarpene-type heterocycles. The unsubstituted parent