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pro vyhledávání: '"Jillian L. Brechbiel"'
Publikováno v:
The Journal of Neuroscience. 33:14791-14800
Intracellular mRNA localization is a conserved mechanism for spatially regulating protein production in polarized cells, such as neurons. The mRNA encoding the translational repressor Nanos (Nos) forms ribonucleoprotein (RNP) particles that are dendr
Publikováno v:
Toxicologic Pathology. 39:478-485
The advent of molecular targeted therapies offers the hope of therapeutic advance in the fight against cancer. However, this hope is tempered by recent findings that certain targeted therapies may have unique side effects. The Hedgehog (HH) pathway i
Publikováno v:
Developmental Biology. 282(1):207-217
Developmental control of translation is frequently mediated by regulatory elements that reside within 3′ untranslated regions (3′ UTRs). Two stem-loops within the nanos 3′ UTR translational control element (TCE) act independently to direct tran
Publikováno v:
Molecular Cancer Therapeutics. 8:C110-C110
Current treatment for the most common pediatric brain tumor, medulloblastoma (MB) compromises neurological and endocrine development, particularly in younger patients. Mutations in Patched (PTCH1), the receptor for Hedgehog (Hh) proteins, cause MB in
Publikováno v:
Journal of Neuroscience; 9/11/2013, Vol. 33 Issue 37, p14791-14800a, 11p
Publikováno v:
Toxicologic Pathology; Apr2011, Vol. 39 Issue 3, p478-485, 8p