Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jillian L, Astarita"'
Autor:
Alessandra Castiglioni, Yagai Yang, Katherine Williams, Alvin Gogineni, Ryan S. Lane, Amber W. Wang, Justin A. Shyer, Zhe Zhang, Stephanie Mittman, Alan Gutierrez, Jillian L. Astarita, Minh Thai, Jeffrey Hung, Yeqing Angela Yang, Tony Pourmohamad, Patricia Himmels, Marco De Simone, Justin Elstrott, Aude-Hélène Capietto, Rafael Cubas, Zora Modrusan, Wendy Sandoval, James Ziai, Stephen E. Gould, Wenxian Fu, Yulei Wang, James T. Koerber, Shomyseh Sanjabi, Ira Mellman, Shannon J. Turley, Sören Müller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract TGFβ signaling is associated with non-response to immune checkpoint blockade in patients with advanced cancers, particularly in the immune-excluded phenotype. While previous work demonstrates that converting tumors from excluded to inflamed
Externí odkaz:
https://doaj.org/article/fa5b40b8c1aa4ad3abed292446b9c3af
Autor:
Jillian L. Astarita, Shilpa Keerthivasan, Bushra Husain, Yasin Şenbabaoğlu, Erik Verschueren, Sarah Gierke, Victoria C. Pham, Sean M. Peterson, Cecile Chalouni, Andrew A. Pierce, Jennie R. Lill, Lino C. Gonzalez, Nadia Martinez-Martin, Shannon J. Turley
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
The cancer-associated fibroblast (CAF) marker podoplanin (PDPN) is generally correlated with poor clinical outcomes in cancer patients and thus represents a promising therapeutic target. Despite its biomedical relevance, basic aspects of PDPN biology
Externí odkaz:
https://doaj.org/article/87b716521ce444d8bffa72f85fd9fcc7
Autor:
Shannon J. Turley, Michael C. Carroll, Glenn Dranoff, Ellen Pure, Kai W. Wucherpfennig, Martin LaFleur, Anne L. Fletcher, Konstantin Knoblich, Sara Cruz Migoni, Tyler Laszewski, Zohreh Amoozgar, Stephen Santoro, Lotte Spel, Michael Wu, Matthew C. Woodruff, Kenzie MacIsaac, Shilpa Keerthivasan, Angelo L. Grauel, Jillian L. Astarita, Viviana Cremasco
Supplementary Figures 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7f02dabeff083fbdb6805103383305
https://doi.org/10.1158/2326-6066.22538908
https://doi.org/10.1158/2326-6066.22538908
Autor:
Shannon J. Turley, Michael C. Carroll, Glenn Dranoff, Ellen Pure, Kai W. Wucherpfennig, Martin LaFleur, Anne L. Fletcher, Konstantin Knoblich, Sara Cruz Migoni, Tyler Laszewski, Zohreh Amoozgar, Stephen Santoro, Lotte Spel, Michael Wu, Matthew C. Woodruff, Kenzie MacIsaac, Shilpa Keerthivasan, Angelo L. Grauel, Jillian L. Astarita, Viviana Cremasco
Figure legends for Supplementary Figures 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbad9e3a2a9b7925edcdf852a07f117
https://doi.org/10.1158/2326-6066.22538911.v1
https://doi.org/10.1158/2326-6066.22538911.v1
Autor:
Shannon J. Turley, Michael C. Carroll, Glenn Dranoff, Ellen Pure, Kai W. Wucherpfennig, Martin LaFleur, Anne L. Fletcher, Konstantin Knoblich, Sara Cruz Migoni, Tyler Laszewski, Zohreh Amoozgar, Stephen Santoro, Lotte Spel, Michael Wu, Matthew C. Woodruff, Kenzie MacIsaac, Shilpa Keerthivasan, Angelo L. Grauel, Jillian L. Astarita, Viviana Cremasco
Cancer-associated fibroblasts (CAFs) are generally associated with poor clinical outcome. CAFs support tumor growth in a variety of ways and can suppress antitumor immunity and response to immunotherapy. However, a precise understanding of CAF contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597f4fcee53dde229bdecdf8997f2d58
https://doi.org/10.1158/2326-6066.c.6548938.v1
https://doi.org/10.1158/2326-6066.c.6548938.v1
Autor:
Alessandra Castiglioni, Markus Brown, Jillian L. Astarita, Mark Z. Chen, Lucinda Tam, Richard Bourgon, Claudia X. Dominguez, Shilpa Keerthivasan, Cecile Chalouni, Wendy Sandoval, Viviana Cremasco, Xiumin Wu, Yeqing Angela Yang, Andrey S. Shaw, Frederic J. de Sauvage, Ira Mellman, Elaine E. Storm, Catherine B Carbone, Merone Roose-Girma, Zora Modrusan, Amber W. Wang, Akshay T. Krishnamurty, Yasin Senbabaoglu, Wyne P. Lee, Jonas Doerr, Maximilian Nitschké, Shannon J. Turley, Varun N. Kapoor, Ryan Lane, Sören Müller, Christine Moussion
Publikováno v:
Nature Immunology. 22:571-585
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2383e3a737dd8c2478d0ddc2038bf224
https://doi.org/10.1038/s41590-021-00920-6
https://doi.org/10.1038/s41590-021-00920-6
Autor:
Richard L. Boyd, Joana Campos, Burkhard Ludewig, Anne L. Fletcher, Mechthild Luetge, Scott N. Mueller, J. D'Rozario, C. Perez Shibayama, Shannon J. Turley, Alice E Denton, E. Dutton, David Roberts, Yannick O. Alexandre, Konstantin Knoblich, Muath Suliman, Jillian L. Astarita, Hung-Wei Cheng, T. Heng
SummaryThe lymph node (LN) is home to resident macrophage populations that are essential for immune function and homeostasis. The T cell paracortical zone is a major site of macrophage efferocytosis of apoptotic cells, but key factors controlling thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6da7ad67004004acce2714d3858ef2b8
https://doi.org/10.1101/2021.11.24.469855
https://doi.org/10.1101/2021.11.24.469855
Autor:
Stephen Santoro, Shilpa Keerthivasan, Viviana Cremasco, Kai W. Wucherpfennig, Lotte Spel, Matthew C. Woodruff, Jillian L. Astarita, Sara Cruz Migoni, Angelo Grauel, Michael P Wu, Martin W. LaFleur, Kenzie MacIsaac, Konstantin Knoblich, Tyler Laszewski, Michael C. Carroll, Shannon J. Turley, Ellen Puré, Anne L. Fletcher, Zohreh Amoozgar, Glenn Dranoff
Publikováno v:
Cancer Immunology Research. 6:1472-1485
Cancer-associated fibroblasts (CAFs) are generally associated with poor clinical outcome. CAFs support tumor growth in a variety of ways and can suppress antitumor immunity and response to immunotherapy. However, a precise understanding of CAF contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f581fea41fa85e387c8b80ca0ef93393
https://doi.org/10.1158/2326-6066.cir-18-0098
https://doi.org/10.1158/2326-6066.cir-18-0098
Autor:
Varun N, Kapoor, Sören, Müller, Shilpa, Keerthivasan, Markus, Brown, Cecile, Chalouni, Elaine E, Storm, Alessandra, Castiglioni, Ryan, Lane, Maximilian, Nitschke, Claudia X, Dominguez, Jillian L, Astarita, Akshay T, Krishnamurty, Catherine B, Carbone, Yasin, Senbabaoglu, Amber W, Wang, Xiumin, Wu, Viviana, Cremasco, Merone, Roose-Girma, Lucinda, Tam, Jonas, Doerr, Mark Z, Chen, Wyne P, Lee, Zora, Modrusan, Yeqing Angela, Yang, Richard, Bourgon, Wendy, Sandoval, Andrey S, Shaw, Frederic J, de Sauvage, Ira, Mellman, Christine, Moussion, Shannon J, Turley
Publikováno v:
Nature immunology. 22(5)
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c34433813cfb4eea728ece92310aea55
https://pubmed.ncbi.nlm.nih.gov/34088748
https://pubmed.ncbi.nlm.nih.gov/34088748
Autor:
Hanane Touil, Brendan Heiden, Samuel K. Ludwin, Paul O'Connor, Jennifer L. Gommerman, Valera Castanov, Deepali Malhotra, Robert Kay, Shannon J. Turley, Alexandre Prat, Natalia Pikor, Amit Bar-Or, Lesley A. Ward, Joy Qu, Susan J. Armstrong, Georgina Galicia, Jillian L. Astarita, Valeria Ramaglia, Louis Boon, Leslie Summers-Deluca, Claudia X. Dominguez
Publikováno v:
Immunity. 43:1160-1173
SummaryTertiary lymphoid tissues (TLTs) have been observed in the meninges of multiple sclerosis (MS) patients, but the stromal cells and molecular signals that support TLTs remain unclear. Here, we show that T helper 17 (Th17) cells induced robust T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b547f45c5affc06f1f8d68dd215386ef
https://doi.org/10.1016/j.immuni.2015.11.010
https://doi.org/10.1016/j.immuni.2015.11.010