Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jillian Howlin"'
Autor:
Malin Dahlgren, Barbara Lettiero, Hina Dalal, Kira Mårtensson, Alexander Gaber, Björn Nodin, Sofia K. Gruvberger-Saal, Lao H. Saal, Jillian Howlin
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Objective To investigate CITED1 as a potential biomarker of anti-endocrine response and breast cancer recurrence, given its previously determined role in mediating estrogen-dependant transcription. The study is a continuation of earlier work
Externí odkaz:
https://doaj.org/article/c9c6f678180546e18206439af403ab2a
Autor:
Eleonor Olsson, Christof Winter, Anthony George, Yilun Chen, Jillian Howlin, Man‐Hung Eric Tang, Malin Dahlgren, Ralph Schulz, Dorthe Grabau, Danielle van Westen, Mårten Fernö, Christian Ingvar, Carsten Rose, Pär‐Ola Bendahl, Lisa Rydén, Åke Borg, Sofia K Gruvberger‐Saal, Helena Jernström, Lao H Saal
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 8, Pp 1034-1047 (2015)
Abstract Metastatic breast cancer is usually diagnosed after becoming symptomatic, at which point it is rarely curable. Cell‐free circulating tumor DNA (ctDNA) contains tumor‐specific chromosomal rearrangements that may be interrogated in blood p
Externí odkaz:
https://doaj.org/article/c10d86508cf44e4580dc8c94b5230785
Autor:
Jillian Howlin, Helena Cirenajwis, Barbara Lettiero, Johan Staaf, Martin Lauss, Lao Saal, Åke Borg, Sofia Gruvberger-Saal, Göran Jönsson
Publikováno v:
PeerJ, Vol 3, p e788 (2015)
CITED1 is a non-DNA binding transcriptional co-regulator whose expression can distinguish the ‘proliferative’ from ‘invasive’ signature in the phenotype-switching model of melanoma. We have found that, in addition to other ‘proliferative’
Externí odkaz:
https://doaj.org/article/26b94c3967e141e886bf3e6c9fd50fb9
Autor:
Malin Dahlgren, Barbara Lettiero, Hina Dalal, Kira Mårtensson, Alexander Gaber, Björn Nodin, Sofia K. Gruvberger-Saal, Lao H. Saal, Jillian Howlin
OBJECTIVE: We present our observations of CITED1 as a potential biomarker of anti-endocrine treatment response and recurrence in breast cancer and suggest that this is dependent on its role in mediating a specific ERα transcriptional response. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b68fe371f298cf63be7f8d9bf76bdf
https://doi.org/10.21203/rs.3.rs-2304366/v1
https://doi.org/10.21203/rs.3.rs-2304366/v1
Autor:
Bengt Phung, Per Eystein Lønning, Jillian Howlin, Frida Rosengren, Mattias Aine, Rizwan Haq, Göran Jönsson, Martin Lauss, Karolina Holm, Markus Ringnér, David E. Fisher, Karin Jirström, Katja Harbst, Johan Staaf, Christian Busch, Åke Borg, Jürgen Geisler, Helena Cirenajwis
Publikováno v:
Journal of Investigative Dermatology. 135(7):1820-1828
The microphthalmia-associated transcription factor (MITF) is a key regulator of melanocyte development and a lineage-specific oncogene in melanoma; a highly lethal cancer known for its unpredictable clinical course. MITF is regulated by multiple intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0be4b1d9c3a5e4e35f40e7f3ea7da2
Autor:
Sofia K. Gruvberger-Saal, Katja Harbst, Christian Ingvar, Linda Werner-Hartman, Anders Kvist, Kari Nielsen, Erik Fredlund, Henrik Ekedahl, Frida Rosengren, Åke Borg, Helena Cirenajwis, Håkan Olsson, Lao H. Saal, Hensin Tsao, Ana Carneiro, Martin Lauss, Göran Jönsson, Lotta Lundgren, Jillian Howlin, Markus Ringnér, Johan Staaf, Karin Jirström, Pär-Ola Bendahl, Jens Enoksson, Therese Törngren
Publikováno v:
Oncotarget
ResearcherID
Oncotarget; 6(14), pp 12297-12309 (2015)
ResearcherID
Oncotarget; 6(14), pp 12297-12309 (2015)
Melanoma is currently divided on a genetic level according to mutational status. However, this classification does not optimally predict prognosis. In prior studies, we have defined gene expression phenotypes (high-immune, pigmentation, proliferative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2b44dfa515b9ed118c6317b63512c8
http://europepmc.org/articles/PMC4494939
http://europepmc.org/articles/PMC4494939
Autor:
Åke Borg, Göran Jönsson, Sofia K. Gruvberger-Saal, Martin Lauss, Jillian Howlin, Barbara Lettiero
We previously demonstrated how CITED1 knockdown in melanoma cells had the capacity to perturb expression of a significant number of genes that comprised MITF and several of its known transcriptional targets. This manifest as a switch from a more inva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2bc61ac8c881b4f2da7caf8ae88fae
Publikováno v:
Methods in Molecular Biology ISBN: 9781493964734
Mammary Gland Development
Mammary Gland Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0936708221a35b64d70c94e88e32d9d
https://doi.org/10.1007/978-1-4939-6475-8
https://doi.org/10.1007/978-1-4939-6475-8
Autor:
Jean, McBryan, Jillian, Howlin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1501
During the past 25 years, the combination of increasingly sophisticated gene targeting technology with transplantation techniques has allowed researchers to address a wide array of questions about postnatal mammary gland development. These in turn ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56537ee5f0af910ddc9d3b4f2ee8a4a8
https://pubmed.ncbi.nlm.nih.gov/27796948
https://pubmed.ncbi.nlm.nih.gov/27796948
Autor:
Jean McBryan, Jillian Howlin
Publikováno v:
Methods in Molecular Biology ISBN: 9781493964734
During the past 25 years, the combination of increasingly sophisticated gene targeting technology with transplantation techniques has allowed researchers to address a wide array of questions about postnatal mammary gland development. These in turn ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3418b2b59bfdcc9ea9787fa0434faa4a
https://doi.org/10.1007/978-1-4939-6475-8_3
https://doi.org/10.1007/978-1-4939-6475-8_3