Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jillian F. Evans"'
Autor:
Stella Bähr, Ryan W. Rue, Carly J. Smith, Jillian F. Evans, Hubert Köster, Vera P. Krymskaya, Dirk Pleimes
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1236 (2024)
Lymphangioleiomyomatosis (LAM) is a rare genetic lung disease. Unfortunately, treatment with the mTORC1 inhibitor Rapamycin only slows disease progression, and incomplete responses are common. Thus, there remains an urgent need to identify new target
Externí odkaz:
https://doaj.org/article/c90f637d5ed241ea8b8500a37e58a7ee
Autor:
Susan M. Lin, Ryan Rue, Akansha Goel, Kseniya Obraztsova, Alexander R. Mukhitov, Kanth Swaroop Vanka, Carly J. Smith, Maria C. Basil, Laura T. Ferguson, Joseph D. Planer, Edward Cantu, Grazyna Kwapiszewska, Edward E. Morrisey, Jillian F. Evans, Vera P. Krymskaya
Pulmonary vascular remodeling is the key structural abnormality in pulmonary hypertension (PH). Mechanistic target of rapamycin (mTOR) has long been suspected to play a role in the development of pulmonary vascular remodeling. However, underlying cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da666a5cd4a35e3f11b5da871f4e9bda
https://doi.org/10.1101/2022.10.08.511300
https://doi.org/10.1101/2022.10.08.511300
Autor:
Bähr, Stella1,2 (AUTHOR) baehr@scinspire.org, Rue, Ryan W.2,3 (AUTHOR), Smith, Carly J.2,3 (AUTHOR), Evans, Jillian F.3 (AUTHOR), Köster, Hubert4 (AUTHOR), Krymskaya, Vera P.3 (AUTHOR), Pleimes, Dirk2 (AUTHOR) baehr@scinspire.org
Publikováno v:
Biomolecules (2218-273X). Oct2024, Vol. 14 Issue 10, p1236. 15p.
Publikováno v:
Clinical & Experimental Allergy Reviews. 1:205-209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2384f6730af00eeda489b0da16e1eed9
https://doi.org/10.1046/j.1472-9725.2001.t01-1-00007.x
https://doi.org/10.1046/j.1472-9725.2001.t01-1-00007.x
Autor:
Robert Zamboni, Jocelyne Guay, Stella Charleson, M.D. Percival, Jean-Pierre Falgueyret, Joseph A. Mancini, Susan Boyce, Michael J. Therien, Lijing Xu, R. Gordon, Stacia Kargman, Anthony W. Ford-Hutchinson, Gillian Greig, Marc Ouellet, Denis Riendeau, Petpiboon Prasit, Serge Leger, Zhaoyin Wang, J.K. Webb, Diane Ethier, Chi-Chung Chan, Gary P. O'Neill, Robert N. Young, Ian W. Rodger, Wanda Cromlish, Christine Brideau, Jillian F. Evans, Michael J. Gresser, E. Wong
Publikováno v:
British Journal of Pharmacology. 121:105-117
1. DFU (5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl)phenyl-2(5H)-furan one) was identified as a novel orally active and highly selective cyclo-oxygenase-2 (COX-2) inhibitor. 2. In CHO cells stably transfected with human COX isozymes, DFU inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d6be69fbb7dddbb45a523b118c18f94
https://doi.org/10.1038/sj.bjp.0701076
https://doi.org/10.1038/sj.bjp.0701076
Autor:
M Cartwright, Stella Charleson, J Frank, Jillian F. Evans, Denis Riendeau, Stacia Kargman, Joseph A. Mancini, Gary P. O'Neill
Publikováno v:
Gastroenterology. 111:445-454
BACKGROUND & AIMS: In the gastrointestinal tract, prostaglandins are implicated as important mediators of normal physiological processes. Prostaglandin G/H synthase (PGHS) is the first enzyme leading to the formation of prostaglandins. Two forms exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a85bf52cec1301af4cddbba809a9bb
https://doi.org/10.1053/gast.1996.v111.pm8690211
https://doi.org/10.1053/gast.1996.v111.pm8690211
Autor:
Irwin I. Singer, L. Hearn, Philip J. Vickers, Diane Ethier, Jillian F. Evans, Stella Charleson, S Scott, J A Heibein, J. W. Woods
Publikováno v:
The Journal of Experimental Medicine
The intracellular distribution of the enzyme 5-lipoxygenase (5-LO) and 5-lipoxygenase-activating protein (FLAP) in resting and ionophore-activated human leukocytes has been determined using immuno-electronmicroscopic labeling of ultrathin frozen sect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362fb37fb60d7dd26efb48408c4d02a2
https://doi.org/10.1084/jem.178.6.1935
https://doi.org/10.1084/jem.178.6.1935
Autor:
Yves Girard, C. S. Mcfarlane, Jillian F. Evans, Denis Riendeau, Donald W. Nicholson, H. Piechuta, Stella Charleson, Stacia Kargman, Dwight Macdonald, Karst Hoogsteen, John Scheigetz, John H. Hutchinson, Thomas R. Jones, Michael J. Therien, Jean-Pierre Falgueyret
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18432bb338fa7f5b2840a8eb597ab6ab
https://doi.org/10.1002/chin.199610195
https://doi.org/10.1002/chin.199610195
Autor:
JS Swaney, TJ Seiders, CS Baccei, P Fagan, Jillian F. Evans, A M Santini, PC Prodanovich, TA Parr, J. H. Hutchinson, LD Correa, DS Lorrain, RA Bundey, Petpiboon Prasit, C Chapman, KJ Stebbins
The aim of this study was to assess the potential of an antagonist selective for the lysophosphatidic acid receptor, LPA(1), in treating lung fibrosis We evaluated the in vitro and in vivo pharmacological properties of the high affinity, selective, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb659d2677e2bbd216e7d64f6d7bacc
https://europepmc.org/articles/PMC2936842/
https://europepmc.org/articles/PMC2936842/
Publikováno v:
The Journal of Cell Biology
In a previous study, osteosarcoma cells expressing both 5-lipoxygenase (5-LO) and 5 lipoxygenase-activating protein (FLAP) synthesized leukotrienes upon A23187 stimulation (Dixon, R. A. F., R. E. Diehl, E. Opas, E. Rands, P. J. Vickers, J. F. Evans,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802cfcf85b459da0819fff8240fccc82
https://doi.org/10.1083/jcb.119.6.1701
https://doi.org/10.1083/jcb.119.6.1701