Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jillian E. Milanes"'
Autor:
Colm P. Roster, Danielle LaVigne, Jillian E. Milanes, Emily Knight, Heidi D. Anderson, Sabrina Pizarro, Elijah M. Harding, Meredith T. Morris, Victoria C. Yan, Cong-Dat Pham, Florian Muller, Samuel Kwain, Kerrick C. Rees, Brian Dominy, Daniel C. Whitehead, Md Nasir Uddin, Steven W. Millward, James C. Morris
Publikováno v:
Pathogens, Vol 12, Iss 11, p 1290 (2023)
Glucose metabolism is critical for the African trypanosome, Trypanosoma brucei, serving as the lone source of ATP production for the bloodstream form (BSF) parasite in the glucose-rich environment of the host blood. Recently, phosphonate inhibitors o
Externí odkaz:
https://doaj.org/article/2fce50c159fa411eb6a7644d59c82260
Publikováno v:
F1000Research, Vol 9 (2021)
Background: Eating or skipping breakfast for weight interests scientific and lay communities. Our objective was to systematically review and meta-analyze causal effects of eating versus skipping breakfast on obesity-related anthropometric outcomes in
Externí odkaz:
https://doaj.org/article/a2d0f9850bad44f3b3303cf57d61db1b
Autor:
Yijian Qiu, Jillian E. Milanes, Jessica A. Jones, Rooksana E. Noorai, Vijay Shankar, James C. Morris
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT The African trypanosome has evolved mechanisms to adapt to changes in nutrient availability that occur during its life cycle. During transition from mammalian blood to insect vector gut, parasites experience a rapid reduction in environmenta
Externí odkaz:
https://doaj.org/article/d57ad760a6a54dfe8ae2289b3c146b36
Autor:
Jillian E. Milanes, Jimmy Suryadi, Neil P. Monaghan, Elijah M. Harding, Corbin S. Morris, Soren D. Rozema, Muhammad M. Khalifa, Jennifer E. Golden, Isabelle Q. Phan, Rachael Zigweid, Jan Abendroth, Christopher A. Rice, Hayden T. McCord, Stevin Wilson, Michael K. Fenwick, James C. Morris
Publikováno v:
Antimicrob Agents Chemother
Infection with pathogenic free-living amoebae, including Naegleria fowleri, Acanthamoeba spp., and Balamuthia mandrillaris, can lead to life-threatening illnesses, primarily because of catastrophic central nervous system involvement. Efficacious trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e07507698ac61ce58ce4a37e32ebead
https://doi.org/10.1128/aac.02373-21
https://doi.org/10.1128/aac.02373-21
Autor:
Daniel C. Whitehead, Jennifer E. Golden, Yijian Qiu, Jillian E. Milanes, Heeren M. Gordhan, James Morris, Kenneth A. Christensen
Publikováno v:
Chemical Communications. 53:8735-8738
A new drug delivery strategy was investigated for the development of potent anti-parasitic compounds against Trypanosoma brucei, the causative agent of African sleeping sickness. Thus, potent in vitro hexokinase inhibitors were rendered cytotoxic by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2056691ef548938ab29ebdec32e4c99b
https://doi.org/10.1039/c7cc03378h
https://doi.org/10.1039/c7cc03378h
Autor:
Stephen L. Patrick, Kayleigh F. Barrett, Wesley C. Van Voorhis, Muhammad M. Khalifa, James Morris, Soren D. Rozema, Isabelle Q. Phan, Jimmy Suryadi, Jan Abendroth, Jennifer E. Golden, Jillian E. Milanes, David M. Dranow
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Infection with the free-living amoeba Naegleria fowleri leads to life-threatening primary amoebic meningoencephalitis. Efficacious treatment options for these infections are limited and the mortality rate is very high (~98%). Parasite metabolism may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d39dfe850d374519122effd21748fe
https://doi.org/10.1128/aac.02410-18
https://doi.org/10.1128/aac.02410-18
Autor:
Jessica A. Jones, Rooksana E. Noorai, Yijian Qiu, Jillian E. Milanes, Vijay Shankar, James Morris
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
mSphere
mSphere
Salivarian trypanosomes grow in mammals, where they depend on glucose, and as procyclic forms in tsetse flies, where they metabolize proline. Differentiation of bloodstream forms to nongrowing stumpy forms, and to procyclic forms, has been studied ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968c750d79e651cfed7f6b7aa60f4a00
https://journals.asm.org/doi/10.1128/mSphere.00366-18
https://journals.asm.org/doi/10.1128/mSphere.00366-18
Autor:
Jillian E Milanes, Victoria C Yan, Cong-Dat Pham, Florian Muller, Samuel Kwain, Kerrick C Rees, Brian N Dominy, Daniel C Whitehead, Steven W Millward, Madison Bolejack, Roger Shek, Logan Tillery, Isabelle Q Phan, Bart Staker, E Ashley Moseman, Xiang Zhang, Xipeng Ma, Audriy Jebet, Xinmin Yin, James C Morris
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012412 (2024)
Infections with the pathogenic free-living amoebae Naegleria fowleri can lead to life-threatening illnesses including catastrophic primary amoebic meningoencephalitis (PAM). Efficacious treatment options for these infections are lacking and the morta
Externí odkaz:
https://doaj.org/article/cb6c340b2bff4f6ca9f6beb1b6aa1504