Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jillian Dietzold"'
Autor:
Elsje Pienaar, Jansy Sarathy, Brendan Prideaux, Jillian Dietzold, Véronique Dartois, Denise E Kirschner, Jennifer J Linderman
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 8, p e1005650 (2017)
Granulomas are complex lung lesions that are the hallmark of tuberculosis (TB). Understanding antibiotic dynamics within lung granulomas will be vital to improving and shortening the long course of TB treatment. Three fluoroquinolones (FQs) are commo
Externí odkaz:
https://doaj.org/article/b653d7d7e3fc4bb592e4aa0ccdde3f5f
Autor:
Sheetal Verma, Archana Gopalakrishnan, Jillian Dietzold, Wasiulla Rafi, Kamlesh Bhatt, Padmini Salgame, Jill Konowich
Publikováno v:
The Journal of Immunology. 198:741-748
We have reported that TLR2 is crucial for host resistance against chronic Mycobacterium tuberculosis infection; however, which cell types are key players in this response remain unknown. This led us to decipher the relative contribution of TLR2 on no
Autor:
Hsin-Pin Ho Liang, Padmini Salgame, Brendan Prideaux, Firat Kaya, Jansy Sarathy, Marizel Mina, Jillian Dietzold, Denise E. Kirschner, Nadine Alvarez-Cabrera, Véronique Dartois, Landry Blanc, Paul O'Brien, Radojka M. Savic, Elsje Pienaar, Isabela Dias-Freedman, Matthew D. Zimmerman, Jennifer J. Linderman
Publikováno v:
Antimicrobial agents and chemotherapy, vol 63, iss 5
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy
Fluoroquinolones represent the pillar of multidrug-resistant tuberculosis (MDR-TB) treatment, with moxifloxacin, levofloxacin, or gatifloxacin being prescribed to MDR-TB patients. Recently, several clinical trials of “universal” drug regimens, ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c4796489044a91794000c22f649cf4
https://escholarship.org/uc/item/4qr8t1h1
https://escholarship.org/uc/item/4qr8t1h1
Autor:
Padmini Salgame, Madhuri Bhagavathula, Jillian Dietzold, Archana Gopalakrishnan, Sheetal Verma
Publikováno v:
Infection and Immunity. 87
The W-Beijing strain family is globally distributed and is associated with multidrug-resistant tuberculosis (TB) and treatment failure. Therefore, in this study, we examined the contribution of Toll-like receptor 2 (TLR2) to host resistance against M
Autor:
Jillian Dietzold, Jodi Lestner, Véronique Dartois, Isaac B Daudelin, Chao Chen, Matthew D. Zimmerman, Landry Blanc, Steven Park, Pei-Yu Chen, Paul O'Brien, Firat Kaya, Padmini Salgame, Brendan Prideaux, Jansy Sarathy, Isabela Dias-Freedman
Publikováno v:
Antimicrobial Agents and Chemotherapy
Clinical trials and practice have shown that ethambutol is an important component of the first-line tuberculosis (TB) regime. This contrasts the drug's rather modest potency and lack of activity against nongrowing persister mycobacteria. The standard
Publikováno v:
Cellular immunology. 302
Accumulating evidence indicates that inflammatory signals required for maximizing effector T cell generation have opposing effects on the development of memory T cell precursors. Toll-like receptor (TLR)2, and TLR9 significantly contribute to the inf
Publikováno v:
F1000Prime Reports
Lipid mediators play an important role in infection- and tissue injury-driven inflammatory responses and in the subsequent inhibition and resolution of the response. Here, we discuss recent findings that substantiate how Mycobacterium tuberculosis pr
Autor:
Jansy Sarathy, Véronique Dartois, Jillian Dietzold, Elsje Pienaar, Brendan Prideaux, Denise E. Kirschner, Jennifer J. Linderman
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 8, p e1005650 (2017)
PLoS Computational Biology
PLoS Computational Biology
Granulomas are complex lung lesions that are the hallmark of tuberculosis (TB). Understanding antibiotic dynamics within lung granulomas will be vital to improving and shortening the long course of TB treatment. Three fluoroquinolones (FQs) are commo
Publikováno v:
The Journal of Immunology. 192:191.7-191.7
Mycobacterium tuberculosis (Mtb) is known to engage Toll-like receptors (TLR) 2 and 9 on macrophages and dendritic cells to initiate an inflammatory response. Nonetheless, studies in the murine model of tuberculosis revealed minimal involvement of TL
Publikováno v:
The Journal of Immunology. 192:66.8-66.8
Previously, our laboratory has demonstrated that N. brasiliensis (Nb), an intestinal helminth, is able to exacerbate Mtb burden in coinfected Balb/c mice through generation of alternatively activated macrophages (AAMs). To examine the role of host ge