Hand function is already reduced before RA development and reflects subclinical tenosynovitis

Autor: Robin M ten Brinck, Annette H M van der Helm-van Mil, Florus J van der Giesen, Xanthe M E Matthijssen, Elise van Mulligen, Irene Speyer, Jill van Aken, Doortje Isabelle Krijbolder, Sarah J H Khidir

Publikováno v: RMD Open, Vol 9, Iss 1 (2023)

Background Clinically suspect arthralgia (CSA) is characterised by arthralgia of small joints and considered a risk stage for development of rheumatoid arthritis (RA). However, it remains unknown if the function of the hands is already affected and w

Externí odkaz: https://doaj.org/article/d2bd4ce3410d497cbcb6c3734e3f8656

Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: A double-blind, randomized, placebo-controlled trial

Autor: André Peeters, H M J Hulsmans, I. Speyer, Jill van Aken, H. Karel Ronday, Henrike van Dongen, René E. M. Toes, K. Visser, Tom W J Huizinga, LR Lard, M. L. Westedt, Cornelia F Allaart, Ferdinand C. Breedveld

Publikováno v: Arthritis & Rheumatism. 56:1424-1432

Objective To determine whether patients with undifferentiated arthritis (UA; inflammatory, nontraumatic arthritis that cannot be diagnosed using current classification criteria) benefit from treatment with methotrexate (MTX). Methods The PRObable rhe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1b226e6ce668220d3490dbfebc08fe
https://doi.org/10.1002/art.22525

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

Autor: Cornelis L. Verweij, René E. M. Toes, Tom W J Huizinga, Geziena M.Th. Schreuder, Ferdinand C. Breedveld, E. Zanelli, Jill van Aken, Floris A. van Gaalen, René R. P. de Vries, Walther J. van Venrooij

Publikováno v: Arthritis and Rheumatism, 50, 7, pp. 2113-2121
Arthritis & Rheumatism, 50(7), 2113-21. John Wiley and Sons Inc.
van Gaalen, FA, van Aken, J, Huizinga, T W, Schreuder, G M, Breedveld, F C, Zanelli, E, Venrooij, W J, Verweij, C L, Toes, RE & de Vries, R R 2004, ' Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis. ', Arthritis & Rheumatism, vol. 50, no. 7, pp. 2113-21 . https://doi.org/10.1002/art.20316
Arthritis and Rheumatism, 50, 2113-2121

Contains fulltext : 58480.pdf (Publisher’s version ) (Closed access) Objective. The functional role of HLA class II molecules in the pathogenesis of rheumatoid arthritis (RA) is unclear. HLA class II molecules are involved in the interaction betwee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724ebb6b33f7b182ac5d0440153a794e
https://hdl.handle.net/2066/58480