Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Jill W Verlander"'
Autor:
Roy L Sutliff, Erik R Walp, Young Hee Kim, Lori A Walker, Alexander M El-Ali, Jing Ma, Robert Bonsall, Semra Ramosevac, Douglas C Eaton, Jill W Verlander, Laura Hansen, Rudolph L Gleason, Truyen D Pham, Seongun Hong, Vladimir Pech, Susan M Wall
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105101 (2014)
Pendrin is a Cl-/HCO3- exchanger expressed in the apical regions of renal intercalated cells. Following pendrin gene ablation, blood pressure falls, in part, from reduced renal NaCl absorption. We asked if pendrin is expressed in vascular tissue and
Externí odkaz:
https://doaj.org/article/bb1451a941eb423ba64bad8a0b856ab8
Publikováno v:
American Journal of Physiology-Renal Physiology. 324:F12-F29
The renal response to acid-base disturbances involves phenotypic and remodeling changes in the collecting duct. This study examines whether the proximal tubule controls these responses. We examined mice with genetic deletion of proteins present only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf50554e419874c2725cc83c47471a
https://doi.org/10.1152/ajprenal.00175.2022
https://doi.org/10.1152/ajprenal.00175.2022
Autor:
Truyen D, Pham, Anthony J, Elengickal, Jill W, Verlander, Lama, Al-Qusairi, Chao, Chen, Delaney C, Abood, Spencer A, King, Johannes, Loffing, Paul A, Welling, Susan M, Wall
Publikováno v:
Am J Physiol Renal Physiol
Pendrin is an intercalated cell Cl(−)/ [Formula: see text] exchanger thought to participate in K(+)-sparing NaCl absorption. However, its role in K(+) homeostasis has not been clearly defined. We hypothesized that pendrin-null mice will develop hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42e31d5db60909a092df1d5625d8d4b5
https://pubmed.ncbi.nlm.nih.gov/35224991
https://pubmed.ncbi.nlm.nih.gov/35224991
Autor:
Truyen D. Pham, Anthony J. Elengickal, Jill W. Verlander, Lama Al-Qusairi, Chao Chen, Delaney C. Abood, Spencer A. King, Johannes Loffing, Paul A. Welling, Susan M. Wall
Publikováno v:
American Journal of Physiology-Renal Physiology. 322:F486-F497
Pendrin is an apical Cl−/[Formula: see text] exchanger that provides renal K+-sparing NaCl absorption. The pendrin-null kidney has an inability to fully conserve K+ and limits renal K+ loss by downregulating the epithelial Na+ channel (ENaC). Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f42201900b5ff1d3b1e4cf0954a141f7
https://doi.org/10.1152/ajprenal.00378.2021
https://doi.org/10.1152/ajprenal.00378.2021
Publikováno v:
Am J Physiol Renal Physiol
The molecular mechanisms regulating ammonia metabolism are fundamental to acid-base homeostasis. Deletion of the A splice variant of Na(+)-bicarbonate cotransporter, electrogenic, isoform 1 (NBCe1-A) partially blocks the effect of acidosis to increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dd1c421e65796119b857973e377d00
https://doi.org/10.1152/ajprenal.00358.2021
https://doi.org/10.1152/ajprenal.00358.2021
Publikováno v:
Am J Physiol Renal Physiol
There are sex differences in renal ammonia metabolism and structure, many of which are mediated by testosterone. The goal of the present study was to determine the role of renal expression of testosterone’s canonical receptor, androgen receptor (AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167cf486f0156306341f42c1f072d8b1
https://doi.org/10.1152/ajprenal.00260.2021
https://doi.org/10.1152/ajprenal.00260.2021
Autor:
Douglas C. Eaton, Cesar A. Romero, Jill W. Verlander, Truyen D. Pham, Yanhua Wang, Qiang Yue, Yoskaly Lazo-Fernandez, Chao Chen, Monika Thumova, Susan M. Wall
Publikováno v:
J Am Soc Nephrol
Background Aldosterone activates the intercalated cell mineralocorticoid receptor, which is enhanced with hypokalemia. Whether this receptor directly regulates the intercalated cell chloride/bicarbonate exchanger pendrin is unclear, as are potassium'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41c366e1608b1e2a9e8fb4bc433995a
https://doi.org/10.1681/asn.2019050551
https://doi.org/10.1681/asn.2019050551
Autor:
Michael F. Romero, Paul A. Welling, I. David Weiner, Charles S. Wingo, Autumn N. Harris, Jill W. Verlander, Hyun-Wook Lee
Publikováno v:
American Journal of Physiology-Renal Physiology. 318:F402-F421
Hypokalemia increases ammonia excretion and decreases K+excretion. The present study examined the role of the proximal tubule protein NBCe1-A in these responses. We studied mice with Na+-bicarbonate cotransporter electrogenic, isoform 1, splice varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb5fe6d27053171a2023e58f3ad25afb
https://doi.org/10.1152/ajprenal.00481.2019
https://doi.org/10.1152/ajprenal.00481.2019
Autor:
Rohan S. Balkawade, Caroline B. Marshall, Michael R. Crowley, Jill W. Verlander, Chao Chen, David K. Crossman, William L. Clapp
Publikováno v:
American Journal of Physiology-Renal Physiology. 316:F1026-F1040
Conditional gene targeting using Cre recombinase has offered a powerful tool to modify gene function precisely in defined cells/tissues and at specific times. However, in mammalian cells, Cre recombinase can be genotoxic. The importance of including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492950cacc6aa22ab3b7c1039bb21842
https://doi.org/10.1152/ajprenal.00359.2018
https://doi.org/10.1152/ajprenal.00359.2018
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9dce1e1895a2eb708eab1d29b6c5d89
https://doi.org/10.1096/fasebj.2021.35.s1.03464
https://doi.org/10.1096/fasebj.2021.35.s1.03464