Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jill Sergesketter Butler"'
Autor:
Jeannine Gerhardt, Angela D. Bhalla, Jill Sergesketter Butler, James W. Puckett, Peter B. Dervan, Zev Rosenwaks, Marek Napierala
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1218-1227 (2016)
Friedreich’s ataxia (FRDA) is caused by the expansion of GAA repeats located in the Frataxin (FXN) gene. The GAA repeats continue to expand in FRDA patients, aggravating symptoms and contributing to disease progression. The mechanism leading to rep
Externí odkaz:
https://doaj.org/article/a3071ce6743c45e79f2475513624f78e
Publikováno v:
Stem Cells and Development. 25:1788-1800
Friedreich's ataxia (FRDA) is the most common autosomal recessive ataxia. This severe neurodegenerative disease is caused by an expansion of guanine-adenine-adenine (GAA) repeats located in the first intron of the frataxin (FXN) gene, which represses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4b7dbc59ff7fbbb0f9a97c018768f1
https://doi.org/10.1089/scd.2016.0147
https://doi.org/10.1089/scd.2016.0147
Autor:
Yihua Qiu, Steven M. Kornblau, Nianxiang Zhang, Jill Sergesketter Butler, Kevin R. Coombes, Suk Young Yoo, Sharon Y.R. Dent
Publikováno v:
Leukemia & Lymphoma. 58:1207-1218
ASH2L encodes a trithorax group protein that is a core component of all characterized mammalian histone H3K4 methyltransferase complexes, including mixed lineage leukemia (MLL) complexes. ASH2L protein levels in primary leukemia patient samples have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2990571737cca64b9c2e9ef022df74ac
https://doi.org/10.1080/10428194.2016.1235272
https://doi.org/10.1080/10428194.2016.1235272
Autor:
Lindsay A. Bonsignore, Jill Sergesketter Butler, Christine E. Schaner Tooley, Carolyn M. Klinge
Publikováno v:
Oncotarget
// Lindsay A. Bonsignore 1 , Jill Sergesketter Butler 1 , Carolyn M. Klinge 1 , Christine E. Schaner Tooley 1 1 Department of Biochemistry & Molecular Genetics, Center for Genetics and Molecular Medicine, University of Louisville School of Medicine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45584ab32b6c3a66dde83a72c5d9491d
https://doi.org/10.18632/oncotarget.3653
https://doi.org/10.18632/oncotarget.3653
Publikováno v:
Blood. 121:3076-3084
Complex developmental processes such as hematopoiesis require a series of precise and coordinated changes in cellular identity to ensure blood homeostasis. Epigenetic mechanisms help drive changes in gene expression that accompany the transition from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a7c991315f9b012c14125f9aacfe2f
https://doi.org/10.1182/blood-2012-10-451237
https://doi.org/10.1182/blood-2012-10-451237
Autor:
Zev Rosenwaks, Jill Sergesketter Butler, Angela D. Bhalla, Marek Napierala, Jeannine Gerhardt, Peter B. Dervan, James W. Puckett
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1218-1227 (2016)
SummaryFriedreich’s ataxia (FRDA) is caused by the expansion of GAA repeats located in the Frataxin (FXN) gene. The GAA repeats continue to expand in FRDA patients, aggravating symptoms and contributing to disease progression. The mechanism leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe67f14cff63678ebb6879cfdd49e36
https://europepmc.org/articles/PMC5028224/
https://europepmc.org/articles/PMC5028224/
Autor:
Lauren Seyer, Jixue Li, Angela D. Bhalla, David A. Lynch, Jill Sergesketter Butler, Marek Napierala, Jennifer Farmer, Amanda Clark, Urszula Polak, Yanjie Li, Yu Yun Chen
Publikováno v:
Biopreservation and biobanking. 14(4)
Friedreich's ataxia (FRDA) represents a rare neurodegenerative disease caused by expansion of GAA trinucleotide repeats in the first intron of the FXN gene. The number of GAA repeats in FRDA patients varies from approximately 60 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b98222fc4f6b5dc5d679705a1d0890c
https://pubmed.ncbi.nlm.nih.gov/27002638
https://pubmed.ncbi.nlm.nih.gov/27002638
Autor:
Cecilia Zurita-Lopez, Sharon Y.R. Dent, Mark T. Bedford, Jill Sergesketter Butler, Steven Clarke
Publikováno v:
Journal of Biological Chemistry. 286:12234-12244
Multiple enzymes and enzymatic complexes coordinately regulate the addition and removal of post-translational modifications on histone proteins. The oncoprotein Ash2L is a component of the mixed lineage leukemia (MLL) family members 1-4, Setd1A, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3afa8a57b875a51b3c8327bc61ee02
https://doi.org/10.1074/jbc.m110.202416
https://doi.org/10.1074/jbc.m110.202416
Autor:
Courtney M. Tate, Jeremy R. Sanford, Ronald C. Wek, Lakshmi Reddy Palam, Jill Sergesketter Butler, David G. Skalnik
Publikováno v:
DNA and Cell Biology. 28:223-231
CXXC finger protein 1 (CFP1) binds to unmethylated CpG dinucleotides and is required for embryogenesis. CFP1 is also a component of the Setd1A and Setd1B histone H3K4 methyltransferase complexes. Murine embryonic stem (ES) cells lacking CFP1 fail to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bb2da819e189afb66e1a2fe9836080
https://doi.org/10.1089/dna.2009.0854
https://doi.org/10.1089/dna.2009.0854
Publikováno v:
DNA and Cell Biology. 27:533-543
CXXC finger protein 1 (CFP1) is a component of the Setd1A and Setd1B methyltransferase complexes, localizes to euchromatic regions of the genome, and specifically binds unmethylated CpG dinucleotides in DNA. Murine embryos lacking CFP1 exhibit peri-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7974914e14e77b57b5ad19118e8daf81
https://doi.org/10.1089/dna.2007.0714
https://doi.org/10.1089/dna.2007.0714