Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jill Schriewer"'
Publikováno v:
Viruses, Vol 2, Iss 9, Pp 1918-1932 (2010)
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics. One major limitation in this process
Externí odkaz:
https://doaj.org/article/08c1c16d5f5d4d2b967be153cfba6450
Autor:
Nicholas van Buuren, Kristin Burles, Jill Schriewer, Ninad Mehta, Scott Parker, R Mark Buller, Michele Barry
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004326 (2014)
Poxviruses contain large dsDNA genomes encoding numerous open reading frames that manipulate cellular signalling pathways and interfere with the host immune response. The NF-κB signalling cascade is an important mediator of innate immunity and infla
Externí odkaz:
https://doaj.org/article/babb26d7bfd94d77830dcb2059211a6e
Autor:
Wieke Freudenburg, Madhav Gautam, Pradipta Chakraborty, Jared James, Jennifer Richards, Alison S Salvatori, Aaron Baldwin, Jill Schriewer, R Mark L Buller, John A Corbett, Dorota Skowyra
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e52408 (2013)
Autoimmune destruction of insulin producing pancreatic β-cells is the hallmark of type I diabetes. One of the key molecules implicated in the disease onset is the immunoproteasome, a protease with multiple proteolytic sites that collaborates with th
Externí odkaz:
https://doaj.org/article/ce511bb44e184cc4a11634b4d99f5488
Autor:
Susan A Holechek, Karen L Denzler, Michael C Heck, Jill Schriewer, R Mark Buller, Fatema A Legrand, Paulo H Verardi, Leslie A Jones, Tilahun Yilma, Bertram L Jacobs
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77879 (2013)
Post-exposure vaccination with vaccinia virus (VACV) has been suggested to be effective in minimizing death if administered within four days of smallpox exposure. While there is anecdotal evidence for efficacy of post-exposure vaccination this has no
Externí odkaz:
https://doaj.org/article/299781d8cc654d19aee1cd1f56066d3e
Autor:
Shannon McNulty, William Bornmann, Jill Schriewer, Chas Werner, Scott K Smith, Victoria A Olson, Inger K Damon, R Mark Buller, John Heuser, Daniel Kalman
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10884 (2010)
Poxvirus morphogenesis is a complex process that involves the successive wrapping of the virus in host cell membranes. We screened by plaque assay a focused library of kinase inhibitors for those that caused a reduction in viral growth and identified
Externí odkaz:
https://doaj.org/article/c3cdbd17d3ad499a8f6fb142ceed8b14
Autor:
Melissa S. Cobb, Shixin Tao, Katherine Shortt, Magdy Girgis, Jeryl Hauptman, Jill Schriewer, Zaphrirah Chin, Edward Dorfman, Kyle Campbell, Daniel P. Heruth, Ralph V. Shohet, Buddhadeb Dawn, Eugene A. Konorev
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H1091-H1107
Many anticancer therapies cause serious cardiovascular complications that degrade quality of life and cause early mortality in treated patients. Specifically, doxorubicin is known as an effective anticancer agent that causes cardiomyopathy in treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff466cb4ae20745d322bd364d2bd9ab0
https://doi.org/10.1152/ajpheart.00312.2022
https://doi.org/10.1152/ajpheart.00312.2022
Autor:
Daniel Van Aartsen, Christopher S. Eickhoff, Anne S. De Groot, Isaac G. Sakala, Krystal A. Meza, Leonard Moise, William D. Martin, Linda Peng, Daniel F. Hoft, R. Mark L. Buller, Jill Schriewer, Frances Terry
Publikováno v:
Vaccine
Influenza world-wide causes significant morbidity and mortality annually, and more severe pandemics when novel strains evolve to which humans are immunologically naïve. Because of the high viral mutation rate, new vaccines must be generated based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b26f3a7285dde6f725dc8d5f8402583
https://pubmed.ncbi.nlm.nih.gov/31331771
https://pubmed.ncbi.nlm.nih.gov/31331771
Autor:
Zuyue Sun, Ralph V. Shohet, Eugene A. Konorev, Jerry W. Marlin, Jill Schriewer, Mingxin Tang, Frederick R. Taylor
Publikováno v:
Journal of Molecular and Cellular Cardiology. 90:129-138
Elevated ALK4/5 ligands including TGF-β2 and activins have been linked to cardiovascular remodeling and heart failure. Doxorubicin (Dox) is commonly used as a model of cardiomyopathy, a condition that often precedes cardiovascular remodeling and hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338ce389ead428caac343ff9635ab43d
https://doi.org/10.1016/j.yjmcc.2015.12.010
https://doi.org/10.1016/j.yjmcc.2015.12.010
Autor:
Bethany D. Harris, R. Mark L. Buller, Jeffrey A. Speir, Jill Schriewer, Shane Miersch, Sachdev S. Sidhu, Mark R. Walter, Ashlesha Deshpande, Srilalitha Kuruganti
Publikováno v:
Journal of Biological Chemistry. 291:447-461
Exogenous cytokine therapy can induce systemic toxicity, which might be prevented by activating endogenously produced cytokines in local cell niches. Here we developed antibody-based activators of cytokine signaling (AcCS), which recognize cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eafec645956533e80e0f40782576ad9
https://doi.org/10.1074/jbc.m115.665943
https://doi.org/10.1074/jbc.m115.665943
Autor:
Wayne M. Yokoyama, Marco Colonna, Ryan W. Crump, Jill Schriewer, Ed Hembrador, Aaron S. Rapaport, Hanspeter Pircher, Jian Gao, Gaelle Le Friec, Béatrice Plougastel, R. Mark L. Buller, Yaming Wang, Susan Gilfillan, Marina Cella
Publikováno v:
Immunity. 43(6):1112-1124
CD8(+) T cells and NK cells protect from viral infections by killing virally infected cells and secreting interferon-γ. Several inhibitory receptors limit the magnitude and duration of these anti-viral responses. NKG2A, which is encoded by Klrc1, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e665e1ceb739af2ccf45c5aecddc2f