Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jill S. Gregory"'
Autor:
Paul Lang, Svend S. Geertsen, Alex L. Lublin, Michelle C. Potter, Tatiana Gladysheva, Jill S. Gregory, Pascal Rufi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 33, Iss , Pp 101395- (2023)
Previous data have suggested an antiviral effect of teriflunomide, including against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the agent underlying the ongoing COVID-19 pandemic. We undertook an in vitro investigation to evaluate
Externí odkaz:
https://doaj.org/article/0872c9dc7f704eeb91ba9d4ccb3eb041
Autor:
Brian B. Gourlie, Remo Perozzo, Mack Kuo, Andrew Janjigian, James C. Sacchettini, Hiroyuki Iwamoto, Jill S. Gregory, Scott F. Sneddon, Christopher Yee, David Alland, Barry N. Kreiswirth, Mark M. Staveski, Marina Leonard, James M. Musser, David A. Fidock, William R. Jacobs, Hector R. Morbidoni
Publikováno v:
Journal of Biological Chemistry. 278:20851-20859
Tuberculosis and malaria together result in an estimated 5 million deaths annually. The spread of multidrug resistance in the most pathogenic causative agents, Mycobacterium tuberculosis and Plasmodium falciparum, underscores the need to identify act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05c1e437ba7b585d5df0220264c6adaa
https://doi.org/10.1074/jbc.m211968200
https://doi.org/10.1074/jbc.m211968200
Autor:
Alex L. Harris, Todd L. Graybill, Alan L. Maycock, Schmidt Stanley J, I. Kelly Osifo, Jill S. Gregory, Roland E. Dolle
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:393-398
Z-Leu-Arg-(7-methoxynaphthyl)amide (1) is a substrate for calpain I. The specificity constant for 1 ( k cat K m = 1405 ± 40 M−1s−1) is 10x greater than for any previously reported fluorogenic substrate. Using this substrate, a sensitive, continu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73c075bacdd43011abda6fc468651b75
https://doi.org/10.1016/0960-894x(95)00042-r
https://doi.org/10.1016/0960-894x(95)00042-r
Autor:
Alex L. Harris, Todd L. Graybill, Matthew S. Miller, Jill S. Gregory, R. E. Dolle, Osifo Irennegbe K, Schmidt Stanley J
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:387-392
1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a3571efa095641bbe8ad930099730f
https://doi.org/10.1016/0960-894x(95)00041-q
https://doi.org/10.1016/0960-894x(95)00041-q
Autor:
Alex L. Harris, Todd L. Graybill, Matthew S. Miller, Jill S. Gregory, Osifo Irennegbe K, R. E. Dolle, Schmidt Stanley J
Publikováno v:
ChemInform. 26
1,4-Dihydro-4-oxo-3-quinolinecarboxamides are a class of non-peptide reversible inhibitor of human erythrocyte Calpain I. The preparation and in vitro evaluation of these compounds are discussed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d9cf0361226f78f64b3d8af94f335ab
https://doi.org/10.1002/chin.199529175
https://doi.org/10.1002/chin.199529175
Autor:
Amanda M. Gillum, Hao H. Sun, G. C. Kydd, M. E. Alvarez, Raymond Cooper, C. B. White, Jill S. Gregory, Alex L. Harris
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb15ed935c6a2a0b0c24a7b6cf740b88
https://doi.org/10.1002/chin.199614282
https://doi.org/10.1002/chin.199614282
Autor:
Rinker James M, Bruce Gauvin, Roland E. Dolle, Mark A. Ator, Jill S. Gregory, Alex L. Harris, Todd L. Graybill, Mitchell J. Ross
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1375-1380
Azapeptide analogues ii of the α-halomethyl ketones i were synthesized and evaluated as potential inhibitors of serine and cysteine proteases. Inhibitors ii discriminate between the two classes of protease, demonstrating selectivity for cysteine pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50907707494c84b00b517f4ba0e96d43
https://doi.org/10.1016/s0960-894x(00)80516-8
https://doi.org/10.1016/s0960-894x(00)80516-8
Publikováno v:
Biochemistry. 30:278-286
In rat 1 fibroblasts, insulin has little or no stimulatory effect on the activities of either MAP2 protein kinase or ribosomal protein S6 kinase. In contrast, in rat 1 cells that overexpress the normal human insulin receptor (rat 1 HIRc B; McClain et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a64865e48e735a456e6308eeeefd57
https://doi.org/10.1021/bi00215a038
https://doi.org/10.1021/bi00215a038
Publikováno v:
Journal of Biological Chemistry. 265:2713-2719
The abilities of a series of six mutants of the human insulin receptor, an insulin receptor/v-ros hybrid (IR-ros) and the P68gag-ros transforming protein to stimulate S6 protein kinase have been assessed. Insulin receptor mutants in which either 1 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fe31217539bf67127854108b84d3087
https://doi.org/10.1016/s0021-9258(19)39860-6
https://doi.org/10.1016/s0021-9258(19)39860-6
Autor:
Mack R, Kuo, Hector R, Morbidoni, David, Alland, Scott F, Sneddon, Brian B, Gourlie, Mark M, Staveski, Marina, Leonard, Jill S, Gregory, Andrew D, Janjigian, Christopher, Yee, James M, Musser, Barry, Kreiswirth, Hiroyuki, Iwamoto, Remo, Perozzo, William R, Jacobs, James C, Sacchettini, David A, Fidock
Publikováno v:
The Journal of biological chemistry. 278(23)
Tuberculosis and malaria together result in an estimated 5 million deaths annually. The spread of multidrug resistance in the most pathogenic causative agents, Mycobacterium tuberculosis and Plasmodium falciparum, underscores the need to identify act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0ed4350d696b7fc15d3c5f0d2ae2d73
https://pubmed.ncbi.nlm.nih.gov/12606558
https://pubmed.ncbi.nlm.nih.gov/12606558