Melanoma-Derived Extracellular Vesicles Induce CD36-Mediated Pre-Metastatic Niche

Autor: Shankar Suman, Wendy K. Nevala, Alexey A. Leontovich, Caitlin Ward, James W. Jakub, Yohan Kim, Liyi Geng, Noah A. Stueven, Chathu L. Atherton, Raymond M. Moore, Jill M. Schimke, Fabrice Lucien-Matteoni, Sarah A. McLaughlin, Svetomir N. Markovic

Publikováno v: Biomolecules, Vol 14, Iss 7, p 837 (2024)

CD36 expression in both immune and non-immune cells is known to be directly involved in cancer metastasis. Extracellular vesicles (EVs) secreted by malignant melanocytes play a vital role in developing tumor-promoting microenvironments, but it is unc

Externí odkaz: https://doaj.org/article/aea87e2bdc6e4ec9bf216716f6fc9d04

Supplementary Figure 1 from Resolving the Heterogeneous Tumor-Centric Cellular Neighborhood through Multiplexed, Spatial Paracrine Interactions in the Setting of Immune Checkpoint Blockade

Autor: Svetomir N. Markovic, Yiyi Yan, Betty A. Dicke, Jill M. Schimke, Ruifeng Guo, Thomas J. Flotte, Wendy K. Nevala, Laura Becher, Raymond M. Moore, Alexey A. Leontovich, Rachel L.G. Maus

Phenotypic Cell Classification Tree

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebacac4564579b8b3cb3634460e2a4b
https://doi.org/10.1158/2767-9764.22544142.v1

Supplementary Table 1 from Resolving the Heterogeneous Tumor-Centric Cellular Neighborhood through Multiplexed, Spatial Paracrine Interactions in the Setting of Immune Checkpoint Blockade

Autor: Svetomir N. Markovic, Yiyi Yan, Betty A. Dicke, Jill M. Schimke, Ruifeng Guo, Thomas J. Flotte, Wendy K. Nevala, Laura Becher, Raymond M. Moore, Alexey A. Leontovich, Rachel L.G. Maus

Antibody reagents and validation for MxIF panel design

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3691a20a6ec1f9ffdeb952832d8402f0
https://doi.org/10.1158/2767-9764.22544136

Supplementary Figure 2 from Resolving the Heterogeneous Tumor-Centric Cellular Neighborhood through Multiplexed, Spatial Paracrine Interactions in the Setting of Immune Checkpoint Blockade

Autor: Svetomir N. Markovic, Yiyi Yan, Betty A. Dicke, Jill M. Schimke, Ruifeng Guo, Thomas J. Flotte, Wendy K. Nevala, Laura Becher, Raymond M. Moore, Alexey A. Leontovich, Rachel L.G. Maus

Virtual H&E images for whole excisional lymph node biopsies from each clinical case

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73479462f18056784e9e6b108311aec7
https://doi.org/10.1158/2767-9764.22544139.v1

Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging

Autor: Surendra Dasari, Brian A. Irving, K. Sreekumaran Nair, Matthew L. Johnson, Dawn M. Morse, Adam R. Konopka, Carrie J. Heppelmann, H. Robert Bergen, Mikkel H. Vendelbo, Daniel R. Jakaitis, Katherine A. Klaus, Ian R. Lanza, Jill M. Schimke, Gregory C. Henderson, Matthew M. Robinson

Publikováno v: Johnson, M L, Irving, B A, Lanza, I R, Vendelbo, M H, Konopka, A R, Robinson, M M, Henderson, G C, Klaus, K A, Morse, D M, Heppelmann, C, Bergen, H R, Dasari, S, Schimke, J M, Jakaitis, D R & Nair, K S 2015, ' Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging ', Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, vol. 70, no. 11, pp. 1386-93 . https://doi.org/10.1093/gerona/glu221

Acute aerobic exercise increases reactive oxygen species and could potentially damage proteins, but exercise training (ET) enhances mitochondrial respiration irrespective of age. Here, we report a differential impact of ET on protein quality in young

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04189c50c5601bd48a115686509303db
https://doi.org/10.1093/gerona/glu221