Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jill M. O'Reilly"'
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 61:73-77
The JAr choriocarcinoma cell cultures have demonstrated high levels of aromatase activity and have been useful for assaying a wide variety of aromatase inhibitors for aromatase inhibition in intact cells. Recently, several 7alpha-arylaliphatic androg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f46e8288a260f29ab9cb97cc3fa10df
https://doi.org/10.1016/s0960-0760(97)00006-x
https://doi.org/10.1016/s0960-0760(97)00006-x
Autor:
Michael V. Darby, Anne L. Quinn, Carl J. Lovely, Xin Ju Gu, David C. Baker, Jill M. O'Reilly, Nancy E. Gilbert, Patrick J Ward, Robert W. Brueggemeier
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 61:247-254
The inhibition of aromatase, the enzyme responsible for converting androgens to estrogens, is therapeutically useful for the endocrine treatment of hormone-dependent breast cancer. Research by our laboratory has focused on developing competitive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c84fc2fdd1c14722aae0a3eb6345433f
https://doi.org/10.1016/s0960-0760(97)80019-2
https://doi.org/10.1016/s0960-0760(97)80019-2
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 59:93-102
Inhibition of aromatase, the enzyme responsible for converting androgens to estrogens, may be therapeutically useful for the endocrine treatment of hormone-dependent breast cancer. Previous research on 7alpha-thiosubstituted androgens, especially 7al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb01771503fada2ab8181059f32dc3b
https://doi.org/10.1016/s0960-0760(96)00087-8
https://doi.org/10.1016/s0960-0760(96)00087-8
Publikováno v:
Current Medicinal Chemistry. 3:11-22
Abstract: Aromatase (estrogen synthase) is an enzyme complex responsible for the conversion of androgens to estrogens in the final step in steroidogenesis. Estrogens play important roles in both normal physiology and reproduction and in certain estro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec78134f518a97a941279135cf7e0c3
https://doi.org/10.2174/092986730301220224161537
https://doi.org/10.2174/092986730301220224161537
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::958f96951441f2ee432ddcd9a1fc7841
https://doi.org/10.1002/chin.199547237
https://doi.org/10.1002/chin.199547237
Publikováno v:
Journal of medicinal chemistry. 38(15)
The inhibition of aromatase, the cytochrome P450 enzyme complex responsible for the conversion of androgens to estrogens, may be useful for the endocrine treatment of breast cancer. Previously, several 7 alpha-thio-substituted androstenediones have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8d5c646e07a5659cd10cede25d1f97
https://pubmed.ncbi.nlm.nih.gov/7636845
https://pubmed.ncbi.nlm.nih.gov/7636845