Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Jill M. Lahti"'
Autor:
Ester Sala, Celia Vived, Júlia Luna, Noemí Alejandra Saavedra-Ávila, Upasana Sengupta, A. Raúl Castaño, Sabrina Villar-Pazos, Laura Haba, Joan Verdaguer, Ana B. Ropero, Thomas Stratmann, Javier Pizarro, Manuel Vázquez-Carrera, Angel Nadal, Jill M. Lahti, Conchi Mora
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundPancreatic islets are exposed to strong pro-apoptotic stimuli: inflammation and hyperglycemia, during the progression of the autoimmune diabetes (T1D). We found that the Cdk11(Cyclin Dependent Kinase 11) is downregulated by inflammation in
Externí odkaz:
https://doaj.org/article/43d700c8d29a47dc8cba0c3b8b15aa2f
Autor:
Steven M. Frisch, Daniel C. Flynn, Jill M. Lahti, Andrea Dorfleutner, David Wallach, Tae Bong Kang, Kristiina Vuori, Angel Cipres, Darren Finlay, Bernard C. Boswell, Brooke Helfer
Supplementary Figure S6 from Caspase-8 Promotes Cell Motility and Calpain Activity under Nonapoptotic Conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00af874ec3ea14736a29ebe44b82467a
https://doi.org/10.1158/0008-5472.22365567
https://doi.org/10.1158/0008-5472.22365567
Autor:
Dwayne G. Stupack, David Schlaepfer, Jill M. Lahti, Daniela Barilà, Matthew Bogyo, David Mikolon, David J. Shields, Tal Teitz, Vicente Torres, Ainhoa Mielgo, Simone Barbero
Caspase-8 is a proapoptotic protease that suppresses neuroblastoma metastasis by inducing programmed cell death. Paradoxically, caspase-8 can also promote cell migration among nonapoptotic cells; here, we show that caspase-8 can promote metastasis wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d922643cc33627dcebaea2a62885ce7c
https://doi.org/10.1158/0008-5472.c.6499511.v1
https://doi.org/10.1158/0008-5472.c.6499511.v1
Autor:
Steven M. Frisch, Daniel C. Flynn, Jill M. Lahti, Andrea Dorfleutner, David Wallach, Tae Bong Kang, Kristiina Vuori, Angel Cipres, Darren Finlay, Bernard C. Boswell, Brooke Helfer
Significant caspase-8 activity has been found in normal and certain tumor cells, suggesting that caspase-8 possesses an alternative, nonapoptotic function that may contribute to tumor progression. In this article, we report that caspase-8 promotes ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098de694186a50d535aed5a3c0753bb3
https://doi.org/10.1158/0008-5472.c.6494751.v1
https://doi.org/10.1158/0008-5472.c.6494751.v1
Autor:
Jill M. Lahti, William A. Weiss, Razqallah Hakem, Marcelo Rubinstein, Christopher Calabrese, Melissa D. Johnson, Yong-Dong Wang, David Finkelstein, Wei Zhao, Jerold E. Rehg, Kejin Zhu, Marcus B. Valentine, Madoka Inoue, Tal Teitz
XLSX file - 146K, Table S1- Data on the genes that differ in expression between primary tumors Th- MYCN, Caspase-8 wild type levels with no BMM, and primary tumors Th-MYCN, deficient caspase-8 with BMM (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1604bde03acdbf7a90a6ad2c3f1de4f6
https://doi.org/10.1158/0008-5472.22396701
https://doi.org/10.1158/0008-5472.22396701
Autor:
Jill M. Lahti, William A. Weiss, Razqallah Hakem, Marcelo Rubinstein, Christopher Calabrese, Melissa D. Johnson, Yong-Dong Wang, David Finkelstein, Wei Zhao, Jerold E. Rehg, Kejin Zhu, Marcus B. Valentine, Madoka Inoue, Tal Teitz
PDF file - 709K, Figure S1. Correlation of relative mean fold changes in expression of genes and microRNAs of the mouse tumor groups by expression- array and by quantitative RT-PCR. Figure S2. Levels of caspase-8 protein in primary tumors and BM seco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185d8f602f95d7334f1b2e67df055e29
https://doi.org/10.1158/0008-5472.22396704
https://doi.org/10.1158/0008-5472.22396704
Autor:
Jill M. Lahti, William A. Weiss, Razqallah Hakem, Marcelo Rubinstein, Christopher Calabrese, Melissa D. Johnson, Yong-Dong Wang, David Finkelstein, Wei Zhao, Jerold E. Rehg, Kejin Zhu, Marcus B. Valentine, Madoka Inoue, Tal Teitz
XLSX file - 77K, Table S3- Data on the microRNAs that differ in expression between primary tumors Th- MYCN, Caspase-8 wild type levels with no BMM, and primary tumors Th-MYCN, deficient caspase-8 with BMM (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5da3c1b855ae032872844cc27f711f
https://doi.org/10.1158/0008-5472.22396692.v1
https://doi.org/10.1158/0008-5472.22396692.v1
Autor:
Dwayne G. Stupack, David Schlaepfer, Jill M. Lahti, Daniela Barilà, Matthew Bogyo, David Mikolon, David J. Shields, Tal Teitz, Vicente Torres, Ainhoa Mielgo, Simone Barbero
Supplementary Figures 1-5 from Caspase-8 Association with the Focal Adhesion Complex Promotes Tumor Cell Migration and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2156c4984120c33221dec024c9ea71d9
https://doi.org/10.1158/0008-5472.22380269.v1
https://doi.org/10.1158/0008-5472.22380269.v1
Autor:
Steven M. Frisch, Daniel C. Flynn, Jill M. Lahti, Andrea Dorfleutner, David Wallach, Tae Bong Kang, Kristiina Vuori, Angel Cipres, Darren Finlay, Bernard C. Boswell, Brooke Helfer
Supplementary Figure Legends S1-S10 from Caspase-8 Promotes Cell Motility and Calpain Activity under Nonapoptotic Conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb217e3d82580a161441150e6b6f832
https://doi.org/10.1158/0008-5472.22365588.v1
https://doi.org/10.1158/0008-5472.22365588.v1
Autor:
Jill M. Lahti, William A. Weiss, Razqallah Hakem, Marcelo Rubinstein, Christopher Calabrese, Melissa D. Johnson, Yong-Dong Wang, David Finkelstein, Wei Zhao, Jerold E. Rehg, Kejin Zhu, Marcus B. Valentine, Madoka Inoue, Tal Teitz
Neuroblastoma, the most common extracranial pediatric solid tumor, is responsible for 15% of all childhood cancer deaths. Patients frequently present at diagnosis with metastatic disease, particularly to the bone marrow. Advances in therapy and under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f565d6c31315b958882848007b07e3
https://doi.org/10.1158/0008-5472.c.6504633.v1
https://doi.org/10.1158/0008-5472.c.6504633.v1