Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jill M. Fritz"'
Publikováno v:
Nature Reviews. Immunology
The T lymphocyte, especially its capacity for antigen-directed cytotoxicity, has become a central focus for engaging the immune system in the fight against cancer. Basic science discoveries elucidating the molecular and cellular biology of the T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6ff46329b6895d5735135ce262b312
http://europepmc.org/articles/PMC7238960
http://europepmc.org/articles/PMC7238960
Autor:
Jill M Fritz, Timothy E Weaver
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107473 (2014)
ERdj4 is a BiP cochaperone regulated by the unfolded protein response to facilitate degradation of unfolded and/or misfolded proteins in the endoplasmic reticulum. As the unfolded protein response plays a critical role in B cell maturation and antibo
Externí odkaz:
https://doaj.org/article/a9c1f9e4b053462d8ce3301dc30336d6
Autor:
Satoshi Kubo, Jill M. Fritz, Hayley M. Raquer-McKay, Rhea Kataria, Ivan Vujkovic-Cvijin, Ahmad Al-Shaibi, Yikun Yao, Lixin Zheng, Juan Zou, Alex D. Waldman, Xinyi Jing, Taylor K. Farley, Ann Y. Park, Andrew J. Oler, Adrian K. Charles, Melanie Makhlouf, Eman H. AbouMoussa, Reem Hasnah, Luis R. Saraiva, Sundar Ganesan, Abdulrahman Ahmed Al-Subaiey, Helen Matthews, Emilio Flano, Hyun Hee Lee, Alexandra F. Freeman, Asena Pınar Sefer, Ersin Sayar, Erkan Çakır, Elif Karakoc-Aydiner, Safa Baris, Yasmine Belkaid, Ahmet Ozen, Bernice Lo, Michael J. Lenardo
Publikováno v:
Nature immunology. 23(1)
We report a pleiotropic disease due to loss-of-function mutations in RHBDF2, the gene encoding iRHOM2, in two kindreds with recurrent infections in different organs. One patient had recurrent pneumonia but no colon involvement, another had recurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dfff11ac6fc2a78495279c1fbec6d2
https://pubmed.ncbi.nlm.nih.gov/34937930
https://pubmed.ncbi.nlm.nih.gov/34937930
Publikováno v:
Blood. 128:1037-1042
CTLA-4 is a critical inhibitory “checkpoint” molecule of immune activation. Several recent reports have described patients with immune dysregulation and lymphoproliferative disease resulting from 2 different genetic diseases that directly or indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2612221075aadfb46275e48ff0a874b2
https://doi.org/10.1182/blood-2016-04-712612
https://doi.org/10.1182/blood-2016-04-712612
Autor:
Lisa R. Young, Chrysi Kanellopoulou, Kejian Zhang, Shannon Nortman, Hilary Haines, Jill M. Fritz, Jason D. Hughes, Susan Price, Michael J. Lenardo, Wei Lu, Yu Zhang, Diane Kissell, Helen C. Su, Rebecca A. Marsh, Vijaya Chaturvedi, Michael B. Jordan, Jack J. Bleesing, Zhiduo Liu, Michael C. Stephens, Joshua J McElwee, Peter Mustillo, Lixin Zheng, Elif Karakoc-Aydiner, Helen F. Matthews, Jun Mo, V. Koneti Rao, Bernice Lo, Alexandra H. Filipovich, Kasper Hoebe, Cesar M. Rueda, Ammar Husami, Claire A. Chougnet, Qian Zhang
Publikováno v:
Science. 349:436-440
Trafficking from bedside to bench Typically in translational research, a discovery in cell or molecular biology is later exploited to improve patient care. Occasionally, information flows in the opposite direction. Lo et al. found that patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68a164d731b5c4eba5dcc14b3d2978cd
https://doi.org/10.1126/science.aaa1663
https://doi.org/10.1126/science.aaa1663
Autor:
Li Yang, Ian P. Lewkowich, Marsha Wills-Karp, Jill M. Fritz, Timothy E. Weaver, Karen S. Apsley
Publikováno v:
The Journal of Immunology. 194:5635-5643
Allergic asthma is a chronic inflammatory disorder that affects ∼20% of the population worldwide. Microarray analyses of nasal epithelial cells from acute asthmatic patients detected a 50% decrease in expression of Stard7, an intracellular phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d623c425e655cf3542f5e6c8d5b938e2
https://doi.org/10.4049/jimmunol.1500231
https://doi.org/10.4049/jimmunol.1500231
Autor:
Sonia S. Majri, Chrysi Kanellopoulou, Behdad Afzali, Jill M. Fritz, Matthew Biancalana, Stefania Pittaluga, Benjamin Chaigne-Delalande, Lixin Zheng, Gulbu Uzel, José Cohen, Steven M. Holland, John J. O'Shea, Juha Grönholm, Alejandro V. Villarino, Michael J. Lenardo, Ashleigh A. Sun, Julie E. Niemela
Understanding the control of Ag restimulation-induced T cell death (RICD), especially in cancer immunotherapy, where highly proliferating T cells will encounter potentially large amounts of tumor Ags, is important now more than ever. It has been know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c489aa84ede441111a381e238b9b29c4
https://europepmc.org/articles/PMC5736408/
https://europepmc.org/articles/PMC5736408/
Autor:
Jean-Claude Sirard, Sabrina Laouami, Anne Derbise, Henry T. Akinbi, Nadine Lemaître, Jill M. Fritz, Florent Sebbane, François Pierre, Maud Merchez, Isabelle Ricard, Ivo G. Boneca, Elizabeth Pradel
Publikováno v:
The Journal of Infectious Diseases. 207:1535-1543
Background. Yersinia pestis (the plague bacillus) and its ancestor, Yersinia pseudotuberculosis (which causes self-limited bowel disease), encode putative homologues of the periplasmic lysozyme inhibitor Ivy and the membrane-bound lysozyme inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afba2491ef59e639035f756d766ab61d
https://doi.org/10.1093/infdis/jit057
https://doi.org/10.1093/infdis/jit057
Autor:
Bernice, Lo, Kejian, Zhang, Wei, Lu, Lixin, Zheng, Qian, Zhang, Chrysi, Kanellopoulou, Yu, Zhang, Zhiduo, Liu, Jill M, Fritz, Rebecca, Marsh, Ammar, Husami, Diane, Kissell, Shannon, Nortman, Vijaya, Chaturvedi, Hilary, Haines, Lisa R, Young, Jun, Mo, Alexandra H, Filipovich, Jack J, Bleesing, Peter, Mustillo, Michael, Stephens, Cesar M, Rueda, Claire A, Chougnet, Kasper, Hoebe, Joshua, McElwee, Jason D, Hughes, Elif, Karakoc-Aydiner, Helen F, Matthews, Susan, Price, Helen C, Su, V Koneti, Rao, Michael J, Lenardo, Michael B, Jordan
Publikováno v:
Science (New York, N.Y.). 349(6246)
Mutations in the LRBA gene (encoding the lipopolysaccharide-responsive and beige-like anchor protein) cause a syndrome of autoimmunity, lymphoproliferation, and humoral immune deficiency. The biological role of LRBA in immunologic disease is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::569c1d4f85855afc7069b127a12e02bf
https://pubmed.ncbi.nlm.nih.gov/26847262
https://pubmed.ncbi.nlm.nih.gov/26847262
Autor:
Timothy E. Weaver, Jill M. Fritz, Mei Dong, Sneha Sitaraman, Cheng-Lun Na, Emily P. Martin, Karen S. Apsley
Publikováno v:
Molecular Biology of the Cell
The BiP cochaperone ERdj4 removes misfolded proteins from the ER lumen by associating with ERAD machinery. Global deficiency of ERdj4 results in widespread constitutive ER stress, decreased survival, and metabolic derangements in mice. These findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9f11395e8da75306370886ba8284f6
https://pubmed.ncbi.nlm.nih.gov/24336520
https://pubmed.ncbi.nlm.nih.gov/24336520