Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jill M Lindley"'
Autor:
Michael A Pfaller, Li Li, Qingmei Liu, Jay Zhang, Michael D Huband, Jill M Lindley, Rodrigo E Mendes
Publikováno v:
JAC-Antimicrobial Resistance
Objectives This study evaluated the in vitro activity of KBP-7072 against 413 contemporary surveillance isolates, including subsets with known tetracycline resistance genes. Materials In total, 105 Klebsiella pneumoniae (51 tetracycline resistant), 1
Autor:
Debora Rubio-Aparicio, Olga Lomovskaya, Mariana Castanheira, Jeffery S. Loutit, Dongxu Sun, Kirk Nelson, Jill M. Lindley, Ruslan Tsivkovski, Michael N. Dudley
Publikováno v:
Antimicrobial Agents and Chemotherapy
QPX7728 is an ultrabroad-spectrum beta-lactamase inhibitor with potent inhibition of key serine and metallo beta-lactamases. QPX7728 enhances the potency of multiple beta-lactams in beta-lactamase-producing Enterobacterales and Acinetobacter spp. In
Autor:
Qingmei Liu, Rodrigo E. Mendes, Jay Zhang, Vincent Benn, Michael D. Huband, Min Zhang, Li Li, Xiaojuan Tan, Robert K. Flamm, Michael A. Pfaller, Jill M. Lindley, Gregory J. Strand
Publikováno v:
Antimicrob Agents Chemother
KBP-7072 is a novel third-generation tetracycline (aminomethylcycline) antibacterial that overcomes common efflux and ribosomal protection resistance mechanisms that cause resistance in older-generation tetracyclines. KBP-7072 completed phase 1 clini
Autor:
Evelyn J. Ellis-Grosse, Kim Sweeney, Dee Shortridge, Jill M. Lindley, Robert K. Flamm, Paul R. Rhomberg
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
The effects of combining fosfomycin with various antimicrobial agents were evaluated in vitro by broth microdilution checkerboard and time-kill kinetic studies. Checkerboard analyses were used to evaluate the following 30 Gram-negative isolates: 5 Ps
Autor:
Jay Zhang, Min Zhang, Li Li, Vincent Benn, Xiaojuan Tan, Rodrigo E. Mendes, Guizhen Zhong, Jill M. Lindley, Kelley A. Fedler, Robert K. Flamm, Michael D. Huband
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 98:115191
This study evaluated the in vitro activity of KHP-3757 (a novel LpxC inhibitor) and comparator agents against recent, geographically diverse, Pseudomonas aeruginosa isolates from a global surveillance program as well as molecularly characterized exte