Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jill K. Edwards"'
Autor:
Robert B. Fogel, Karen Schory, Jill K. Edwards, R. Doug McEvoy, Amy S. Jordan, Peter Catcheside, Chang-Kook Yang, Atul Malhotra, David P. White
Publikováno v:
The Journal of Physiology. 558:993-1004
The termination of obstructive respiratory events is typically associated with arousal from sleep. The ventilatory response to arousal may be an important determinant of subsequent respiratory stability/instability and therefore may be involved in pe
Autor:
Robert B. Fogel, David P. White, Robert J Pierce, John Trinder, Jill K. Edwards, Judy Dunai, Atul Malhotra, Darci Kleverlaan
Publikováno v:
The Journal of Physiology. 553:533-544
Pharyngeal dilator muscles are clearly important in the pathophysiology of obstructive sleep apnoea syndrome (OSA). We have previously shown that the activity of both the genioglossus (GGEMG) and tensor palatini (TPEMG) are decreased at sleep onset,
Autor:
Jill K. Edwards, John Trinder, Michael L. Stanchina, Karen Schory, David P. White, Atul Malhotra, Robert B. Fogel
Publikováno v:
Sleep. 26:851-856
STUDY OBJECTIVES Previous studies in both awake and sleeping humans have demonstrated that lung-volume changes substantially affect upper-airway size and pharyngeal resistance and, thus, may influence pharyngeal patency. We sought to systematically i
Autor:
Giora Pillar, Jill K. Edwards, Steven Shea, Atul Malhotra, David P. White, Robert B. Fogel, Josée Beauregard
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 164:2025-2030
Pharyngeal dilator muscle activation (GGEMG) during wakefulness is greater in patients with obstructive sleep apnea (OSA) than in healthy control subjects, representing a neuromuscular compensatory mechanism for a more collapsible airway. As previous
Autor:
Jill K. Edwards, Steven Shea, Robert B. Fogel, Giora Pillar, Atul Malhotra, David P. White, Josée Beauregard
Publikováno v:
Respiration Physiology. 127:23-38
Upper airway dilator muscles are phasically activated during respiration. We assessed the interaction between central respiratory drive and local (mechanoreceptive) influences upon genioglossal (GG) activity throughout inspiration. GG(EMG) and airway
Autor:
Robert B. Fogel, David P. White, Josée Beauregard, Jill K. Edwards, Atul Malhotra, Giora Pillar
Publikováno v:
Chest. 120:156-161
Study objectives Obstructive sleep apnea (OSA)is characterized by repetitive pharyngeal collapse during sleep. Several techniques have been proposed to assess the collapsibility ofthe upper airway in awake humans, but sleep-wake comparisons haverarel
Autor:
David P. White, David I. Slamowitz, Atul Malhotra, Jill K. Edwards, Steven Shea, Josie Beauregard, Robert B. Fogel, Gioru Pillar
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 162:1058-1062
The stimuli controlling pharyngeal dilator muscles are poorly defined. Local mechanoreceptors are a leading possibility. To address this, we assessed the relationship between two dilator muscle electromyograms (EMGs, i.e., genioglossus [GG-an inspira
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 162:559-565
Genioglossal muscle (GG) activity is modulated by both chemoreceptive and mechanoreceptive reflexes that help stabilize airway patency. We assessed the effects of blood gas changes, within the range encountered during mild obstructive apnea‐arousal
Publikováno v:
Sleep. 23:543-550
Study Objective: To assess the effect of high local oral nicotine administration on the upper airway (UA) of normal males during wakefulness. Design: Nonrandomized study. Setting: Brigham & Women's Hospital General Clinical Research Center. Participa
Publikováno v:
Europe PubMed Central
STUDY OBJECTIVES To define the influence of topical nasopharyngeal anesthesia on genioglossal EMG responsiveness to both negative pressure and basal muscle activity. The effects on airway mechanics (resistance and collapsibility) were also determined