Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jill Graham"'
Autor:
Pavlina Spiliopoulou, Farasat Kazmi, Francesca Aroldi, Thomas Holmes, David Thompson, Lucinda Griffiths, Cathy Qi, Matthew Parkes, Simon Lord, Gareth J. Veal, David J. Harrison, Vicky M. Coyle, Jill Graham, Thomas R. Jeffry Evans, Sarah P. Blagden
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Purpose 5-fluorouracil (5-FU) is inefficiently converted to the active anti-cancer metabolite, fluorodeoxyuridine-monophosphate (FUDR-MP), is associated with dose-limiting toxicities and challenging administration schedules. NUC-3373 is a ph
Externí odkaz:
https://doaj.org/article/8de199adb6da4ff4b44e74190f835493
Autor:
Todd Cutts, Jill Graham, Jonathan Audet, Andrea Kroeker, Anders Leung, Gary P. Kobinger, Gary Wong, Carissa Embury-Hyatt, Xiangguo Qiu, Darwyn Kobasa, Haiyan Wei, Shihua He
Publikováno v:
Journal of Virology. 90:392-399
Infections with Sudan virus (SUDV), a member of the genus Ebolavirus , result in a severe hemorrhagic fever with a fatal outcome in over 50% of human cases. The paucity of prophylactics and therapeutics against SUDV is attributed to the lack of a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a539e12b28b9d73727c8fb7ffd1851
https://doi.org/10.1128/jvi.02331-15
https://doi.org/10.1128/jvi.02331-15
Autor:
Andrew L. Coveler, Jill Graham, Aimery de Gramont, Kristen K. Ciombor, Lisa Jane Rodgers, Janet Graham, Francesca Aroldi, Benjamin L. Schlechter, Jordan Berlin, Josep Tabernero, Jeffrey W. Clark, T.R. Jeffry Evans, Sarah P. Blagden
Publikováno v:
Journal of Clinical Oncology. 38:TPS274-TPS274
TPS274 Background: Although 5-FU-based regimens such as FOLFOX and FOLFIRI remain the cornerstone of treatment for patients (pts) with colorectal cancer (CRC), their clinical utility is limited by resistance mechanisms and toxicity. Anti-cancer activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84e9d27bee8a2309898b6098832c24a1
https://doi.org/10.1200/jco.2020.38.4_suppl.tps274
https://doi.org/10.1200/jco.2020.38.4_suppl.tps274
Autor:
Elaine McCartney, Martin Eatock, Alanna Morton, Chantevy Pou, Caroline Kelly, David McIntosh, Peter Houston, Anthony J. Chalmers, Susie Cooke, Fiona Thomson, T.R. Jeffry Evans, Claire N. Harrison, A. Duffton, Derek Grose, Miranda Ashton, Jill Graham, Alan Bilsland, Liz-Anne Lewsley, Colin Purcell
Publikováno v:
Journal of Clinical Oncology. 38:709-709
709 Background: Olaparib is a potent inhibitor of PARP-1, which has a critical role in signalling DNA single strand breaks (SSB) as part of the base excision repair pathway, and may have radio-sensitizing effects due to impaired resolution of radiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d892180fc8369736edaf8170c7557b50
https://doi.org/10.1200/jco.2020.38.4_suppl.709
https://doi.org/10.1200/jco.2020.38.4_suppl.709
Publikováno v:
Aging (Albany NY)
The C. elegans germline and somatic gonad are actively developing until the animal reaches adulthood, and then continue to undergo striking changes as the animal ages. Reported changes include a depletion of available sperm, a decrease in oocyte qual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1f2be5e620896a13ceee7b9ee007e8
http://europepmc.org/articles/PMC3378273
http://europepmc.org/articles/PMC3378273
Autor:
Mark Lucanic, Matthew S. Gill, Ida M. Klang, Jason M. Held, Gordon J. Lithgow, Jill Graham, Maithili C. Vantipalli, Bradford W. Gibson
Publikováno v:
Nature
Dietary restriction can extend lifespan in model organisms such as the nematode Caenorhabditis elegans. Although a number of key players in lifespan extension have been identified, little is known about the signals that coordinate the metabolic respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4092d3336b27106ed0ececc059815bb
https://doi.org/10.1038/nature10007
https://doi.org/10.1038/nature10007
Autor:
Melanie van der Loop, James Neufeld, Shawn Babiuk, Yan Zhou, Aleksandar Masic, Yohannes Berhane, Jill Graham, John Pasick, John Copps, Andy Potter, Lorne A. Babiuk, Hana M. Weingartl
Publikováno v:
Vaccine. 29:3118-3123
Influenza virus infections continue to cause production losses in the agricultural industry in addition to being a human public health concern. The primary method to control influenza is through vaccination. However, currently used killed influenza v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb38d20861523b3ded2ec03a0383e026
https://doi.org/10.1016/j.vaccine.2011.02.069
https://doi.org/10.1016/j.vaccine.2011.02.069
Publikováno v:
Clinical and Vaccine Immunology. 17:1398-1406
A panel of monoclonal antibodies (MAbs) was generated from mice immunized with binary ethylenimine (BEI)-inactivated H7N1 (A/TK/ON/18-2/00) virus. Using a dot blot assay, six of seven MAbs reacted with viruses of the H7 subtype, but not with any of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304f88fc3d7f17e0e27e8085ffcdede8
https://doi.org/10.1128/cvi.00023-10
https://doi.org/10.1128/cvi.00023-10
Autor:
Jill Graham, D.C Hurman, L. Slider, N. McMillan, D. Summers, D A Collie, Pamela Levack, Ian Kunkler, R. Rampling, A. Gibson, Robin Grant, Patrick Statham, J. Kidd
Publikováno v:
Clinical Oncology. 14:472-480
Aim: To report details concerning symptoms (especially pain) preceding the development of malignant cord compression (MCC); delays between onset/reporting of symptoms and confirmed diagnosis of MCC; accuracy of investigations carried out. Methods: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c631bb22b8263b65263fb40672e4dc0
https://doi.org/10.1053/clon.2002.0098
https://doi.org/10.1053/clon.2002.0098
Publikováno v:
Palliative Medicine. 10:185-194
A national questionnaire-based survey has found that palliative physicians report lower levels of burnout and similar levels of psychiatric morbidity than those reported by consultants in other specialties. To try to explain these findings, this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a433b4dc229b1ae5d9f2e23f4abff8cb
https://doi.org/10.1177/026921639601000302
https://doi.org/10.1177/026921639601000302