Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jill Coghlan"'
Autor:
Jill Coghlan, Alexander Benet, Preethi Kumaran, Michael Ford, Lawrie Veale, St. John Skilton, Sergei Saveliev, Anna A. Schwendeman
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Post translational modifications (PTMs) have been shown to negatively impact protein efficacy and safety by altering its native conformation, stability, target binding and/or pharmacokinetics. One PTM in particular, shuffled disulfide bonds, has been
Externí odkaz:
https://doaj.org/article/16e26e87fd4d48209bbd271a8751d045
Autor:
Sydney Stern, Jill Coghlan, Vishalakshi Krishnan, Sam G. Raney, Andrew Babiskin, Wenlei Jiang, Robert Lionberger, Xiaoming Xu, Anna Schwendeman, James E. Polli
Publikováno v:
Pharmaceutical Research
Complex generics are generic versions of drug products that generally have complex active ingredients, complex formulations, complex routes of delivery, complex dosage forms, are complex drug-device combination products, or have other characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149075a2477047275ebb52d562d33333
https://doi.org/10.1007/s11095-021-03149-y
https://doi.org/10.1007/s11095-021-03149-y
Publikováno v:
J Pharm Sci
Humira® (adalimumab) by AbbVie has been the top-selling biologic drug product for the last few years – reaching nearly $20 billion in annual sales in 2018. Upon the October 2018 release of four adalimumab biosimilars into the European market, thos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c45f70af9d7c47451a3dc10a4ff952
https://doi.org/10.1016/j.xphs.2021.02.003
https://doi.org/10.1016/j.xphs.2021.02.003
Autor:
Jill Coghlan, Jukyung Kang, John C. Fjeldsted, Daniel A. Polasky, Anna A. Schwendeman, Daniel D. Vallejo, Brandon T. Ruotolo, Ruwan T. Kurulugama, Carolina Rojas Ramírez
Publikováno v:
Analytical chemistry. 93(48)
Ion mobility-mass spectrometry (IM-MS) and collision-induced unfolding (CIU) assays of monoclonal antibody (mAb)-based biotherapeutics have proven sensitive to disulfide bridge structures, glycosylation patterns, and small molecule conjugation levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2da71fc5899695404a5193c57ef0b0f
https://pubmed.ncbi.nlm.nih.gov/34808055
https://pubmed.ncbi.nlm.nih.gov/34808055
Autor:
Tyler S. Hageman, Jill Coghlan, Derek R. White, K. Ilker Sen, Anna Schwendeman, Jukyung Kang, Steven P. Schwendeman, Sergei Saveliev, Alexander Benet, Michael J. Ford, Thomas J. Tolbert, Brandon T. Ruotolo, Sang Yeop Kim, David D. Weis, Daniel D. Vallejo
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 146
Biosimilars are poised to reduce prices and increase patient access to expensive, but highly effective biologic products. However, questions still remain about the degree of similarity and scarcity of information on biosimilar products from outside o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5789c0cb739018af019c6aa816cf0f7b
https://pubmed.ncbi.nlm.nih.gov/31841688
https://pubmed.ncbi.nlm.nih.gov/31841688
Autor:
Fred Carstensen, Jill Coghlan
This Connecticut Poverty Report describes the change in the number and proportion of Connecticut residents living in poverty, and the increase in both number and percent between 1990 and 2010, based on Census Bureau reports. Demographic measures of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc45bd6a57d83439ee7de8c0bbd859c8
http://ccea.uconn.edu/studies/CT-PovertyReport_Final.pdf
http://ccea.uconn.edu/studies/CT-PovertyReport_Final.pdf
Publikováno v:
SSRN Electronic Journal.
This quarter’s conventional CCEA analysis finds indications that the listless economic recovery in Connecticut is slowly strengthening, with performance approaching national growth rates. Looking ahead eight business quarters, this Outlook details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efff62ab4d829a92f986b35d0092c6ca
https://doi.org/10.2139/ssrn.2327953
https://doi.org/10.2139/ssrn.2327953
This study examines the benefits that can emerge specifically in Connecticut during a shift from fossil-fueled to electricity-charged vehicles, with attention to their adoption's affect on electricity rates and transmission lines, and EV potential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______645::cee220537915e0937aa23f5b73eff204
http://ccea.uconn.edu/studies/ElectricVehicles_2011sept.pdf
http://ccea.uconn.edu/studies/ElectricVehicles_2011sept.pdf
For seven years, the All Our Kin, Inc. (AOK) Child Care Licensing Program in helped address the New Haven helped address the area’s vital need for affordable, high-quality child care. CCEA prepared an economic impact study using the REMI dynamic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______645::603763737fd1c3ed7fd3d14221c651d7
http://ccea.uconn.edu/studies/CCEA_AOK-EconImpact_2011jul.pdf
http://ccea.uconn.edu/studies/CCEA_AOK-EconImpact_2011jul.pdf
During the ten-year period that occurs between available Census data for the Fairfield Court HUD project baseline (1999) and data in this report (2009), the nation in general, and Stamford in particular, experienced a strong housing bubble, evidenced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______645::406ac355b1c337ffa7fd0c594dc252ca
http://ccea.uconn.edu/studies/HOPE-VI.CCEA-to-CharterOak_2011apr.pdf
http://ccea.uconn.edu/studies/HOPE-VI.CCEA-to-CharterOak_2011apr.pdf