Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jill C. Merrill"'
Autor:
Amy M. Avila, David B. Carlson, Jill C. Merrill, Jia Yao, Paul Brown, Emily Place, Todd Bourcier, Shwu-Luan Lee, Wafa Harrouk, Ronald L. Wange, Ilona Bebenek, Muriel Saulnier, Karen L. Davis Bruno, Ikram Elayan, Donna L. Mendrick, Dong Zhao, John Dubinion, Jackye Peretz, Jessica A. Bonzo
Publikováno v:
Regulatory Toxicology and Pharmacology. 114:104662
Nonclinical testing of human pharmaceuticals is conducted to assess the safety of compounds to be studied in human clinical trials and for marketing of new drugs. Although there is no exact number and type of nonclinical studies required for safety a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f1872988c1b49b5abc1d069c43b790
https://doi.org/10.1016/j.yrtph.2020.104662
https://doi.org/10.1016/j.yrtph.2020.104662
Publikováno v:
Toxicology. 99(3)
Polybrominated biphenyl (PBB) is an industrial chemical and environmental contaminant with known incidence of significant human exposure. PBB has been studied in laboratory animals and found to have significant toxicological effects as well as being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927a1c634a7da47364e071d1a556f11f
https://pubmed.ncbi.nlm.nih.gov/7610462
https://pubmed.ncbi.nlm.nih.gov/7610462
Publikováno v:
Steroids. 50:51-59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa49eec8ef36be5d333886eef3d3008e
https://doi.org/10.1016/0039-128x(83)90061-2
https://doi.org/10.1016/0039-128x(83)90061-2
Autor:
C. J. Corbin, Claudia T. Evans, C T Saunders, Jill C. Merrill, Evan R. Simpson, Carole R. Mendelson
Publikováno v:
Journal of Biological Chemistry. 262:6914-6920
Using human adipose stromal cells in monolayer culture as a model system for study of the regulation of aromatase activity, as well as polyclonal antibodies raised in this laboratory against aromatase cytochrome P-450 (cytochrome P-450AROM), it was f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1a6f484f1f6fe18d51118cb4dd5835c
https://doi.org/10.1016/s0021-9258(18)48331-7
https://doi.org/10.1016/s0021-9258(18)48331-7
Autor:
Jill C. Merrill, Tammy M. Bray
Publikováno v:
The Journal of Nutrition. 113:1725-1731
The present experiment was designed to determine the effect of tissue concentrations of glutathione (GSH) and GSH-S-transferase activity on 3-methylindole (3MI)-induced pulmonary toxicity in vivo. Forty goats were given high protein, normal protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e86452db13d438c767dfe0e609a7a21
https://doi.org/10.1093/jn/113.9.1725
https://doi.org/10.1093/jn/113.9.1725
Autor:
Jill C. Merrill, Tammy M. Bray
Publikováno v:
Canadian journal of physiology and pharmacology. 60(12)
Low dietary protein has been shown to induce the activity of rat hepatic UDP-glucuronyltransferase (UDPGTase) as measured in vitro. The assay of UDPGTase in vitro is hampered by the need to solubilize the microsomal membrane, without destroying the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667cb86462320f8e4d8f599ec646854c
https://pubmed.ncbi.nlm.nih.gov/6819886
https://pubmed.ncbi.nlm.nih.gov/6819886
Autor:
Alexander J. Hollub, Jill C. Merrill, Evan R. Simpson, Carole R. Mendelson, Sandra E. Graham-Lorence
Publikováno v:
Endocrine reviews. 10(2)
Introduction THE BIOSYNTHESIS of estrogens is catalyzed by an enzyme complex termed aromatase which is localized in the endoplasmic reticulum of cells in which it is expressed. The aromatase enzyme complex consists of two components (1): The first is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977c48b5b900a14a79b3a469b6e62f43
https://pubmed.ncbi.nlm.nih.gov/2666116
https://pubmed.ncbi.nlm.nih.gov/2666116