Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jill Blanchard"'
Autor:
Jeffrey Kurz, Sara Chesworth Keene, John L. Diener, Ryan M. Boomer, Jayaram Srinivasan, Charles Wilson, David Epstein, Markus Kurz, Jill Blanchard, Nobuko Hamaguchi, Sharon T. Cload
Publikováno v:
Chemistry & Biology. 11(4):499-508
Two molecular sensors that specifically recognize ADP in a background of over 100-fold molar excess of ATP are described. These sensors are nucleic-acid based and comprise a general method for monitoring protein kinase activity. The ADP-aptamer scint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6b17205ce2856e3f472a40b63c0777
Autor:
David Epstein, Gustave Bergnes, Carla L. Gilliam, Katharine V. Blake, Kollol Pal, Michael D. Boisclair, Jill Blanchard
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:2849-2854
The four-component Ugi reaction was utilized to prepare a library of dipeptidic compounds in order to explore the binding requirements of the key cell cycle phosphatase, Cdc25. Several phosphate surrogates were incorporated into the Ugi product to mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f976a223ba03f4b283d258b32f718d2
https://doi.org/10.1016/s0960-894x(99)00497-7
https://doi.org/10.1016/s0960-894x(99)00497-7
Autor:
David Epstein, Carla L. Gilliam, Katharine V. Blake, Kollol Pal, Michael D. Boisclair, Jill Blanchard, Gustave Bergnes
Publikováno v:
ChemInform. 31
The four-component Ugi reaction was utilized to prepare a library of dipeptidic compounds in order to explore the binding requirements of the key cell cycle phosphatase, Cdc25. Several phosphate surrogates were incorporated into the Ugi product to mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b11062a675c5265713654948ec92795
https://doi.org/10.1002/chin.200005282
https://doi.org/10.1002/chin.200005282
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:2537-2538
Synthetic dysidiolide, as well as several related compounds containing a gamma-hydroxybutenolide moiety, were tested in in vitro Cdc25 assays against both synthetic and natural substrates. Contrary to literature values which are in the low micromolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2736b71d15bc831819ab8b784d7b26
https://doi.org/10.1016/s0960-894x(99)00431-x
https://doi.org/10.1016/s0960-894x(99)00431-x