Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jill A. Henrich"'
Publikováno v:
Blood. 140:95-96
Autor:
Anilkumar Gopalakrishnapillai, Gerard McGeehan, Jill A Henrich, Haiming Xu, Yaniv Kazansky, Charlie Hatton, Emily B Heikamp, Sonali P. Barwe, Edward A. Kolb, Yanhe Wen, Alex Kentsis, Hannah Uckelmann, Eric M. Wong, Florian Perner, Scott A. Armstrong, Sumiko Takao, Yana Pikman
Publikováno v:
Blood. 139(6)
Translocations involving the NUP98 gene produce NUP98-fusion proteins and are associated with a poor prognosis in acute myeloid leukemia (AML). MLL1 is a molecular dependency in NUP98-fusion leukemia, and therefore we investigated the efficacy of the
Autor:
Brandon J. Aubrey, Jevon A. Cutler, Wallace Bourgeois, Katherine A. Donovan, Shengqing Gu, Charlie Hatton, Sarah Perlee, Florian Perner, Homa Rahnamoun, Alexandra C. P. Theall, Jill A. Henrich, Qian Zhu, Radosław P. Nowak, Young Joon Kim, Salma Parvin, Anjali Cremer, Sarah Naomi Olsen, Nicholas A. Eleuteri, Yana Pikman, Gerard M. McGeehan, Kimberly Stegmaier, Anthony Letai, Eric S. Fischer, X. Shirley Liu, Scott A. Armstrong
Publikováno v:
Nature cancer. 3(5)
Acute myeloid leukemia (AML) remains difficult to treat and requires new therapeutic approaches. Potent inhibitors of the chromatin-associated protein MENIN have recently entered human clinical trials, opening new therapeutic opportunities for some g