Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jill A. Fielhaber"'
Autor:
Kristoff Nelson, Jeffrey Downey, Maziar Divangahi, Antonio Layoun, Ortal Attias, Kwang-Bo Joung, T. Martin Schmeing, Philippe P. Roux, Alexander A. Goldberg, Jill A. Fielhaber, Ayesha Baig, Alexandra Carella, Nahomi Amberber, Arnold S. Kristof, Mikaela Eng, Yingshan Han
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Inactivation of the protein complex ‘mechanistic target of rapamycin complex 1’ (mTORC1) can increase the nuclear content of transcriptional regulators of metabolism and apoptosis. Previous studies established that nuclear import of signal transd
Autor:
Maziar Divangahi, Kwang-Bo Joung, Ortal Attias, T. Martin Schmeing, Alexander A. Goldberg, Alexandra Carella, Jeffrey Downey, Antonio Layoun, Ayesha Baig, Philippe P. Roux, Mikaela Eng, Jill A. Fielhaber, Yingshan Han, Nahomi Amberber, Kristoff Nelson, Arnold S. Kristof
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Inactivation of the protein complex 'mechanistic target of rapamycin complex 1' (mTORC1) can increase the nuclear content of transcriptional regulators of metabolism and apoptosis. Previous studies established that nuclear import of signal transducer
Autor:
Karin Fredriksson, Jill A Fielhaber, Jonathan K Lam, Xianglan Yao, Katharine S Meyer, Karen J Keeran, Gayle J Zywicke, Xuan Qu, Zu-Xi Yu, Joel Moss, Arnold S Kristof, Stewart J Levine
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33984 (2012)
The mammalian target of rapamycin (mTOR) modulates immune responses and cellular proliferation. The objective of this study was to assess whether inhibition of mTOR with rapamycin modifies disease severity in two experimental murine models of house d
Externí odkaz:
https://doaj.org/article/fe03ae8f94ab41ce89c3a47ab2dbd0b5
Autor:
Arnold S. Kristof, Sabah N. A. Hussain, Alexandra Triantafillopoulos, Mitra Shourian, Scott F. Carroll, Anders Bondo Dydensborg, Sharon Harel, Jill A. Fielhaber, Maxime Bouchard, Salman T. Qureshi
Publikováno v:
The Journal of Immunology. 188:4535-4542
Acute lung injury during bacterial infection is associated with neutrophilic inflammation, epithelial cell apoptosis, and disruption of the alveolar-capillary barrier. TLR4 is required for lung injury in animals exposed to bacterial LPS and initiates
Autor:
Philippe P. Roux, Ortal Attias, Jill A. Fielhaber, Jason Tan, Kwang-bo Joung, Stefanie Huegel, Michael Bader, Arnold S. Kristof
Publikováno v:
Journal of Biological Chemistry. 287:14325-14335
Under conditions of reduced mitogen or nutritional substrate levels, the serine/threonine kinase target of rapamycin can augment the nuclear content of distinct transcription factors and promote the induction of stress response genes. In its latent (
Autor:
Arnold S. Kristof, Shuo Xing, Jill A. Fielhaber, Jason Tan, Catherine M. Biggs, Ying Shan Han, Kwang-bo Joung
Publikováno v:
Journal of Biological Chemistry. 284:24341-24353
Target of rapamycin (TOR) is a highly conserved serine/threonine kinase that controls cell growth, primarily via regulation of protein synthesis. In Saccharomyces cerevisiae, TOR can also suppress the transcription of stress response genes by a mecha
Publikováno v:
C98. NOVEL AIRWAY EPITHELIAL BARRIER AND IMMUNE RESPONSES.
Autor:
Joel Moss, Jonathan Lam, Gayle J. Zywicke, Xuan Qu, Katharine S. Meyer, Arnold S. Kristof, Xianglan Yao, Stewart J. Levine, Zu-Xi Yu, Karin Fredriksson, Jill A. Fielhaber, Karen J. Keeran
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33984 (2012)
PLoS ONE
PLoS ONE
The mammalian target of rapamycin (mTOR) modulates immune responses and cellular proliferation. The objective of this study was to assess whether inhibition of mTOR with rapamycin modifies disease severity in two experimental murine models of house d
Autor:
Scott G. Filler, Jill A. Fielhaber, Donald C. Sheppard, R. Robitaille, Norma V. Solis, Michel Laverdière, Paolo Campoli, Arnold S. Kristof, Q. Al Abdallah
Posaconazole prophylaxis has proven highly effective in preventing invasive fungal infections, despite relatively low serum concentrations. However, high tissue levels of this agent have been reported in treated patients. We therefore hypothesized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fdd2624c0382f0f0501bb5dbe05f3a
https://europepmc.org/articles/PMC3232766/
https://europepmc.org/articles/PMC3232766/
Autor:
Karen J. Keeran, Joel Moss, Gayle J. Zywicke, Jonathan Lam, Jill A. Fielhaber, Arnold S. Kristof, Zu Xi Yu, Karin Fredriksson, Stewart J. Levine
Publikováno v:
C36. CRITICAL PATHWAYS IN ALLERGIC INFLAMMATION.