Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Jill A Hollenbach"'
Autor:
Kristen J. Wade, Rayo Suseno, Kerry Kizer, Jacqueline Williams, Juliano Boquett, Stacy Caillier, Nicholas R. Pollock, Adam Renschen, Adam Santaniello, Jorge R. Oksenberg, Paul J. Norman, Danillo G. Augusto, Jill A. Hollenbach
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract The extremely high levels of genetic polymorphism within the human major histocompatibility complex (MHC) limit the usefulness of reference-based alignment methods for sequence assembly. We incorporate a short-read, de novo assembly algorith
Externí odkaz:
https://doaj.org/article/da420c82ac434ddc86e06bc9431d32c9
Autor:
Vincent Damotte, Chao Zhao, Chris Lin, Eric Williams, Yoram Louzoun, Abeer Madbouly, Rochelle Kotlarz, Marissa McDaniel, Paul J. Norman, Yong Wang, Martin Maiers, Jill A. Hollenbach
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-8 (2024)
Abstract Background Questions persist around whether and how to use race or geographic ancestry in biomedical research and medicine, but these forms of self-identification serve as a critical tool to inform matching algorithms for human leukocyte ant
Externí odkaz:
https://doaj.org/article/cc593cf5f8c24223aa1e90a0d2c86c20
Autor:
Qin Ma, Danillo G. Augusto, Gonzalo Montero-Martin, Stacy J. Caillier, Kazutoyo Osoegawa, Bruce A. C. Cree, Stephen L. Hauser, Alessandro Didonna, Jill A. Hollenbach, Paul J. Norman, Marcelo Fernandez-Vina, Jorge R. Oksenberg
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe HLA-DRB1 gene in the major histocompatibility complex (MHC) region in chromosome 6p21 is the strongest genetic factor identified as influencing multiple sclerosis (MS) susceptibility. DNA methylation changes associated with MS have been
Externí odkaz:
https://doaj.org/article/e17816670eb94ed78dd6ec595e2f543c
Autor:
John Mukisa, Marion Amujal, Obondo J. Sande, Moses L. Joloba, Daudi Jjingo, David P. Kateete, Graeme Mardon, Mogomotsi Matshaba, Neil Hanchard, Jill A. Hollenbach
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Host response to the human immune deficiency virus (HIV) involves both the innate and adaptive immune systems. As part of the innate immune system, the killer cell immunoglobulin-like receptors (KIRs) found on natural killer cells and some T
Externí odkaz:
https://doaj.org/article/7b34a82e753f41b8be9e240f53200078
Autor:
Joseph J. Sabatino Jr., Kristen Mittl, William M. Rowles, Kira McPolin, Jayant V. Rajan, Matthew T. Laurie, Colin R. Zamecnik, Ravi Dandekar, Bonny D. Alvarenga, Rita P. Loudermilk, Chloe Gerungan, Collin M. Spencer, Sharon A. Sagan, Danillo G. Augusto, Jessa R. Alexander, Joseph L. DeRisi, Jill A. Hollenbach, Michael R. Wilson, Scott S. Zamvil, Riley Bove
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
BACKGROUND Vaccine-elicited adaptive immunity is a prerequisite for control of SARS-CoV-2 infection. Multiple sclerosis (MS) disease-modifying therapies (DMTs) differentially target humoral and cellular immunity. A comprehensive comparison of the eff
Externí odkaz:
https://doaj.org/article/fbe0d204af4d4ebaa9905f844ad5d93e
Autor:
Venceslas Douillard, Erick C. Castelli, Steven J. Mack, Jill A. Hollenbach, Pierre-Antoine Gourraud, Nicolas Vince, Sophie Limou
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The current SARS-CoV-2 pandemic era launched an immediate and broad response of the research community with studies both about the virus and host genetics. Research in genetics investigated HLA association with COVID-19 based on in silico, population
Externí odkaz:
https://doaj.org/article/832f3f2615a04582b9fbab5288352b51
Autor:
Venceslas Douillard, Erick C. Castelli, Steven J. Mack, Jill A. Hollenbach, Pierre-Antoine Gourraud, Nicolas Vince, Sophie Limou, for the Covid-19|HLA & Immunogenetics Consortium and the SNP-HLA Reference Consortium
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The rapid, global spread of the SARS-CoV-2 virus during the current pandemic has triggered numerous efforts in clinical and research settings to better understand the host genetics’ interactions and the severity of COVID-19. Due to the established
Externí odkaz:
https://doaj.org/article/d1e27b2e91de46be91488cd5c11819eb
Autor:
Wesley M Marin, Ravi Dandekar, Danillo G Augusto, Tasneem Yusufali, Bianca Heyn, Jan Hofmann, Vinzenz Lange, Jürgen Sauter, Paul J Norman, Jill A Hollenbach
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1008904 (2021)
The killer-cell immunoglobulin-like receptor (KIR) complex on chromosome 19 encodes receptors that modulate the activity of natural killer cells, and variation in these genes has been linked to infectious and autoimmune disease, as well as having bea
Externí odkaz:
https://doaj.org/article/4880db1e9f7e492dafc5a56310cfa057
Autor:
Vitor R. C. Aguiar, Danillo G. Augusto, Erick C. Castelli, Jill A. Hollenbach, Diogo Meyer, Kelly Nunes, Maria Luiza Petzl-Erler
Publikováno v:
Genetics and Molecular Biology, Vol 44, Iss 1 suppl 1 (2021)
Abstract Meeting the challenges brought by the COVID-19 pandemic requires an interdisciplinary approach. In this context, integrating knowledge of immune function with an understanding of how genetic variation influences the nature of immunity is a k
Externí odkaz:
https://doaj.org/article/dfb43c8b79404c4d93935ceb43a680b4
Autor:
Lisa E. Creary, Sridevi Gangavarapu, Stacy J. Caillier, Paola Cavalcante, Rita Frangiamore, Benedicte A. Lie, Mats Bengtsson, Hanne Flinstad Harbo, Susanna Brauner, Jill A. Hollenbach, Jorge R. Oksenberg, Pia Bernasconi, Angelina Hatlø Maniaol, Lennart Hammarström, Renato Mantegazza, Marcelo A. Fernández-Viña
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Genetic susceptibility to myasthenia gravis (MG) associates with specific HLA alleles and haplotypes at the class I and II regions in various populations. Previous studies have only examined alleles at a limited number of HLA loci that defined only b
Externí odkaz:
https://doaj.org/article/f9fff5faecf44309a832d4aa10d35395