Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jill, Hazelwood"'
Autor:
Alan Wilson, Iris B. Owusu, Boteju Lakmal W, Saadat Aleem, Philip Manton Brown, Jack Yan, Theodore C. Jessop, David J. Augeri, Suman Layek, Zhong Lai, S. David Kimball, Jill Hazelwood, William Heydorn, Kenneth G. Carson, Tamas Oravecz, Liam Moran, Suma Gopinathan, Haiming Zhang, Michael S. Donoviel, Amr Nouraldeen, William K. Sonnenburg, Jeffrey T. Bagdanoff, Jeffrey A. Kramer, Alan Main, Barbara Brooks, Li Dong, James E. Tarver, Padmaja Yalamanchili, Kenny Frazier, Marianne Carlsen, Mark S. Bednarz
Publikováno v:
Journal of Medicinal Chemistry. 53:8650-8662
Sphingosine 1-phosphate lyase (S1PL) has been characterized as a novel target for the treatment of autoimmune disorders using genetic and pharmacological methods. Medicinal chemistry efforts targeting S1PL by direct in vivo evaluation of synthetic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c87e00a9781c267b0a4f8d1324759661
https://doi.org/10.1021/jm101183p
https://doi.org/10.1021/jm101183p
Autor:
Qingyun Liu, Weimei Sun, Amr Nouraldeen, Lawrence F. Courtney, Alan Wilson, Suman Layek, Marianne Carlsen, Sean Yu, Mark S. Bednarz, Zhong Lai, Ann Marie Digeorge-Foushee, Tamas Oravecz, Jerry A. Taylor, Traci Smith, Haiming Zhang, Liam Moran, Jonathan C. Swaffield, Debra Bruce, Jill Hazelwood, Simon D.P. Baugh, David J. Augeri, Emily O’Neill, Joseph Barbosa, Kristen M. Terranova, Suma Gopinathan, Gardyan Michael Walter, Huy Van Nguyen, S. David Kimball, Jeffrey T. Bagdanoff, Jack Yan, Theodore C. Jessop, Michael S. Donoviel, Qinghong Fu, Jeffrey A. Kramer, Alan Main, James E. Tarver, Kenneth G. Carson
Publikováno v:
Journal of Medicinal Chemistry. 52:3941-3953
During nearly a decade of research dedicated to the study of sphingosine signaling pathways, we identified sphingosine-1-phosphate lyase (S1PL) as a drug target for the treatment of autoimmune disorders. S1PL catalyzes the irreversible decomposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adb6db472626b33c48fc85b6ff019d0
https://doi.org/10.1021/jm900278w
https://doi.org/10.1021/jm900278w
Autor:
Jeffrey T, Bagdanoff, Michael S, Donoviel, Amr, Nouraldeen, Marianne, Carlsen, Theodore C, Jessop, James, Tarver, Saadat, Aleem, Li, Dong, Haiming, Zhang, Lakmal, Boteju, Jill, Hazelwood, Jack, Yan, Mark, Bednarz, Suman, Layek, Iris B, Owusu, Suma, Gopinathan, Liam, Moran, Zhong, Lai, Jeff, Kramer, S David, Kimball, Padmaja, Yalamanchili, William E, Heydorn, Kenny S, Frazier, Barbara, Brooks, Philip, Brown, Alan, Wilson, William K, Sonnenburg, Alan, Main, Kenneth G, Carson, Tamas, Oravecz, David J, Augeri
Publikováno v:
Journal of medicinal chemistry. 53(24)
Sphingosine 1-phosphate lyase (S1PL) has been characterized as a novel target for the treatment of autoimmune disorders using genetic and pharmacological methods. Medicinal chemistry efforts targeting S1PL by direct in vivo evaluation of synthetic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::204bf8f2e5cfe6d6fe7e35186b834e44
https://pubmed.ncbi.nlm.nih.gov/21090716
https://pubmed.ncbi.nlm.nih.gov/21090716