Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Jill, Gilmour"'
Autor:
Natalia Fernandez, Peter Hayes, Julia Makinde, Jonathan Hare, Deborah King, Rui Xu, Ola Rehawi, Allison T. Mezzell, Laban Kato, Susan Mugaba, Jennifer Serwanga, James Chemweno, Eunice Nduati, Matt A. Price, Faith Osier, Christina Ochsenbauer, Ling Yue, Eric Hunter, Jill Gilmour, The IAVI protocol C investigators
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionImmunological protection against human immunodeficiency virus-1 (HIV-1) infection is likely to require both humoral and cell-mediated immune responses, the latter involving cytotoxic CD8 T-cells. Characterisation of CD8 T-cell mediated di
Externí odkaz:
https://doaj.org/article/d09b8b3e2b0944bb84f7e710a4da7f2d
Autor:
Omotayo Farinre, Kamini Gounder, Tarylee Reddy, Marcel Tongo, Jonathan Hare, Beth Chaplin, Jill Gilmour, Phyllis Kanki, Jaclyn K. Mann, Thumbi Ndung’u
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background The HIV-1 epidemic in sub-Saharan Africa is heterogeneous with diverse unevenly distributed subtypes and regional differences in prevalence. Subtype-specific differences in disease progression rate and transmission efficiency have
Externí odkaz:
https://doaj.org/article/333bae7afc7345b0a3a56f5f08174403
Autor:
Samantha McInally, Kristin Wall, Tianwei Yu, Rabindra Tirouvanziam, William Kilembe, Jill Gilmour, Susan A. Allen, Eric Hunter
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background To determine if individuals, from HIV-1 serodiscordant couple cohorts from Rwanda and Zambia, who become HIV-positive have a distinct inflammatory biomarker profile compared to individuals who remain HIV-negative, we compared leve
Externí odkaz:
https://doaj.org/article/56acb69a00cb46d8b38e2f3dfc85d63a
Autor:
Victoria O. Kasprowicz, Denis Chopera, Kim Darley Waddilove, Mark A. Brockman, Jill Gilmour, Eric Hunter, William Kilembe, Etienne Karita, Simani Gaseitsiwe, Eduard J. Sanders, Thumbi Ndung’u
Publikováno v:
BMC Public Health, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Africa bears a disproportionately high burden of globally significant disease but has lagged in knowledge production to address its health challenges. In this contribution, we discuss the challenges and approaches to health resear
Externí odkaz:
https://doaj.org/article/0ab8af7dd65741c58ce02dfffb85b3ef
Autor:
Clive M. Michelo, Andrew Fiore-Gartland, Jama A. Dalel, Peter Hayes, Jianming Tang, Edward McGowan, William Kilembe, Natalia Fernandez, Jill Gilmour, Eric Hunter
Publikováno v:
Vaccines, Vol 11, Iss 2, p 472 (2023)
An effective HIV vaccine will need to stimulate immune responses against the sequence diversity presented in circulating virus strains. In this study, we evaluate breadth and depth estimates of potential T-cell epitopes (PTEs) in transmitted founder
Externí odkaz:
https://doaj.org/article/baeb58724f0f4d479ef70e11b3fdf9fb
Autor:
Gisele Umviligihozo, Erick Muok, Emmanuel Nyirimihigo Gisa, Rui Xu, Dario Dilernia, Kimberley Herard, Heeyah Song, Qianhong Qin, Jean Bizimana, Paul Farmer, Jonathan Hare, Jill Gilmour, Susan Allen, Etienne Karita, Eric Hunter, Ling Yue
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Most studies of HIV-1 transmission have focused on subtypes B and C. In this study, we determined the genomic sequences of the transmitted founder (TF) viruses from acutely infected individuals enrolled between 2005 and 2011 into IAVI protocol C in R
Externí odkaz:
https://doaj.org/article/7da2e3b82b044ac6a40fc81526c004cc
Autor:
Julia Makinde, Eunice W. Nduati, Anna Freni-Sterrantino, Claire Streatfield, Catherine Kibirige, Jama Dalel, S. Lucas Black, Peter Hayes, Gladys Macharia, Jonathan Hare, Edward McGowan, Brian Abel, Deborah King, Sarah Joseph, The IAVI Protocol C Investigators, Eric Hunter, Eduard J. Sanders, Matt Price, Jill Gilmour
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Individuals infected with HIV display varying rates of viral control and disease progression, with a small percentage of individuals being able to spontaneously control infection in the absence of treatment. In attempting to define the correlates ass
Externí odkaz:
https://doaj.org/article/829f97530f9b45ef868ac9271d0434cc
Autor:
Ed McGowan, Rachel Rosenthal, Andrew Fiore-Gartland, Gladys Macharia, Sheila Balinda, Anne Kapaata, Gisele Umviligihozo, Erick Muok, Jama Dalel, Claire L. Streatfield, Helen Coutinho, Dario Dilernia, Daniela C. Monaco, David Morrison, Ling Yue, Eric Hunter, Morten Nielsen, Jill Gilmour, Jonathan Hare
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Predictive models are becoming more and more commonplace as tools for candidate antigen discovery to meet the challenges of enabling epitope mapping of cohorts with diverse HLA properties. Here we build on the concept of using two key parameters, div
Externí odkaz:
https://doaj.org/article/493f151d155947d8b8782e91a188310e
Autor:
Robert K. Langat, Bashir Farah, Jackton Indangasi, Simon Ogola, Gloria Omosa-Manyonyi, Omu Anzala, Jean Bizimana, Emmanuel Tekirya, Caroline Ngetsa, Moses Silwamba, Enoch Muyanja, Paramesh Chetty, Maureen Jangano, Nancy Hills, Jill Gilmour, Len Dally, Josephine H. Cox, Peter Hayes
Publikováno v:
African Journal of Laboratory Medicine, Vol 10, Iss 1, Pp e1-e13 (2021)
Background: Standardisation of procedures for performing cellular functional assays across laboratories participating in multicentre clinical trials is key for generating comparable and reliable data. Objective: This article describes the performanc
Externí odkaz:
https://doaj.org/article/6c9c7f3784614754a32056bcac6e0d60
Autor:
Peter Hayes, Natalia Fernandez, Christina Ochsenbauer, Jama Dalel, Jonathan Hare, Deborah King, Lucas Black, Claire Streatfield, Vanaja Kakarla, Gladys Macharia, Julia Makinde, Matt Price, Eric Hunter, The IAVI protocol C investigators, Jill Gilmour
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Full characterisation of functional HIV-1-specific T-cell responses, including identification of recognised epitopes linked with functional antiviral responses, would aid development of effective vaccines but is hampered by HIV-1 sequence diversity.
Externí odkaz:
https://doaj.org/article/e0b00ac73c00437fa2470b5c5987dc1c