FAIR Digital Twins for Data-Intensive Research

Autor: Erik Schultes, Marco Roos, Luiz Olavo Bonino da Silva Santos, Giancarlo Guizzardi, Jildau Bouwman, Thomas Hankemeier, Arie Baak, Barend Mons

Publikováno v: Frontiers in Big Data, Vol 5 (2022)

Although all the technical components supporting fully orchestrated Digital Twins (DT) currently exist, what remains missing is a conceptual clarification and analysis of a more generalized concept of a DT that is made FAIR, that is, universally mach

Externí odkaz: https://doaj.org/article/aa48be0b66914c24a902475201adafd5

Digital Resilience Biomarkers for Personalized Health Maintenance and Disease Prevention

Autor: Willem van den Brink, Robbert Bloem, Adithya Ananth, Thiru Kanagasabapathi, Arjen Amelink, Jildau Bouwman, Gerwin Gelinck, Sjaak van Veen, Andre Boorsma, Suzan Wopereis

Publikováno v: Frontiers in Digital Health, Vol 2 (2021)

Health maintenance and disease prevention strategies become increasingly prioritized with increasing health and economic burden of chronic, lifestyle-related diseases. A key element in these strategies is the empowerment of individuals to control the

Externí odkaz: https://doaj.org/article/db2dc56ea4db4fa9948a24970103d17a

A Machine Learning Algorithm for Quantitatively Diagnosing Oxidative Stress Risks in Healthy Adult Individuals Based on Health Space Methodology: A Proof-of-Concept Study Using Korean Cross-Sectional Cohort Data

Autor: Youjin Kim, Yunsoo Kim, Jiyoung Hwang, Tim J. van den Broek, Bumjo Oh, Ji Yeon Kim, Suzan Wopereis, Jildau Bouwman, Oran Kwon

Publikováno v: Antioxidants, Vol 10, Iss 7, p 1132 (2021)

Oxidative stress aggravates the progression of lifestyle-related chronic diseases. However, knowledge and practices that enable quantifying oxidative stress are still lacking. Here, we performed a proof-of-concept study to predict the oxidative stres

Externí odkaz: https://doaj.org/article/dc7d9623171e43ab9be08ebf356378b8

Current and Future Nutritional Strategies to Modulate Inflammatory Dynamics in Metabolic Disorders

Autor: Willem van den Brink, Jolanda van Bilsen, Kanita Salic, Femke P. M. Hoevenaars, Lars Verschuren, Robert Kleemann, Jildau Bouwman, Gabriele V. Ronnett, Ben van Ommen, Suzan Wopereis

Publikováno v: Frontiers in Nutrition, Vol 6 (2019)

Obesity, type 2 diabetes, and other metabolic disorders have a large impact on global health, especially in Western countries. An important hallmark of metabolic disorders is chronic low-grade inflammation. A key player in chronic low-grade inflammat

Externí odkaz: https://doaj.org/article/28ccf8f079db45c180c2a580d4d21d61

OBEDIS Core Variables Project: European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions

Autor: António L. Palmeira, Thorkild I. A. Sørensen, Martin Neovius, Martine Laville, Mikael Rydén, Andrea Natali, Maud Alligier, Romain Barrès, Kristina Campbell, David Jacobi, I. Sadaf Farooqi, Jean-Michel Oppert, Helen M. Roche, André Scheen, Karine Clément, Ellen E. Blaak, Yves Boirie, Gijs H. Goossens, Jason C.G. Halford, Luc Tappy, Nathalie Farpour-Lambert, Hannele Yki-Järvinen, Uberto Pagotto, Chantal Simon, Jörg Hager, Jildau Bouwman, Paul Brunault, Gema Frühbeck, Dominique Langin, Olivier Ziegler, Chantal Julia, Hans Hauner

Publikováno v: Alligier, M, Barres, R, Boirie, Y, Bouwman, J, Brunault, P, Campbell, K, Clement, K, Farooqi, I S, Farpour-Lambert, N J, Fruhbeck, G, Goossens, G H, Hager, J, Halford, J C G, Hauner, H, Jacobi, D, Julia, C, Langin, D, Natali, A, Neovius, M, Oppert, J M, Pagotto, U, Palmeira, A L, Roche, H, Ryden, M, Scheen, A J, Simon, C, Sørensen, T I A, Tappy, L, Yki-Jarvinen, H, Ziegler, O & Laville, M 2020, ' OBEDIS Core Variables Project : European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions ', Obesity Facts, vol. 13, no. 1, pp. 1-28 . https://doi.org/10.1159/000505342
Obesity facts, Vol. 13, No 1 (2020) pp. 1-28
Obesity Facts
Obesity Facts, Karger AG, 2020, 13 (1), pp.1-28. ⟨10.1159/000505342⟩
Obesity Facts, Karger AG, 2020, pp.1-28. ⟨10.1159/000505342⟩
Obesity Facts, Vol 13, Iss 1, Pp 1-28 (2020)
Obesity Facts, 2020, 13 (1), pp.1-28. ⟨10.1159/000505342⟩
Obesity Facts, 1, 13, 1-28
Obesity Facts, 13(1), 1-28. Karger

Heterogeneity of interindividual and intraindividual responses to interventions is often observed in randomized, controlled trials for obesity. To address the global epidemic of obesity and move toward more personalized treatment regimens, the global

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d711c76faee4a4c61a58bc169e30d830
https://doi.org/10.1159/000505342