Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Jijing, Pang"'
Autor:
Yan Sun, Dan Xiao, Zhuang Li, Dan Xu, Donglei Zhang, Yuanlong An, Jinyue Xue, Yue Ren, Shu Liu, Di Wang, Jun Li, Zhuoshi Wang, Jijing Pang
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101646- (2024)
Adeno-associated virus (AAV) vectors have been widely used in therapy to treat hereditary retinal diseases. But its transduction efficiency by intravitreal injection still needs to be improved. In this study, we investigated the transduction efficien
Externí odkaz:
https://doaj.org/article/a11a38570d144324b60b075526d1ffdb
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
Leber congenital amaurosis (LCA) is the most common genetic cause of congenital visual impairment in infants and children. Patients with LCA who harbor RPE65 mutations exhibit a deficiency in photoreceptor rhodopsin, leading to severe night blindness
Externí odkaz:
https://doaj.org/article/326596c217744fc7b154b672df4f3f5b
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
X-linked retinoschisis is more common in male children and rare in females. Clinically, male patients mainly present with early onset visual impairment or vision loss, and retinal retinoschisis due to division of the inner retina. We report a long-te
Externí odkaz:
https://doaj.org/article/02b4792617764fa0b34e2dd6a3bb1199
Publikováno v:
European Journal of Ophthalmology. 33:714-722
Purpose Bardet–Biedl syndrome (BBS) is a rare autosomal-recessive inherited disorder characterized by multisystem anomalies. The objective of this study was to detect and analyse pathogenic variants in four Chinese families with BBS. Methods Compre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5683fa02dc937818dc60c9fdaa4975
https://doi.org/10.1177/11206721221136324
https://doi.org/10.1177/11206721221136324
Publikováno v:
Journal of Ophthalmology, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/12332865e6fa44348be691013b9bea9e
Autor:
Qinxiang Zheng, Yueping Ren, Radouil Tzekov, Shanshan Hua, Minghan Li, Jijing Pang, Jia Qu, Wensheng Li
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
Purpose. To investigate the iTRAQ-based proteomic changes of visual cycle-associated proteins in RPE of rd12 mice before and after RPE65 gene delivery. Mehtods. The right eyes of rd12 mice underwent RPE65 gene delivery by subretinal injection at P14,
Externí odkaz:
https://doaj.org/article/2c22dab65f194fc8878294e1e1ed9ec8
Autor:
Yan Qi, Xufeng Dai, Hua Zhang, Ying He, Yangyang Zhang, Juanjuan Han, Ping Zhu, Yuxin Zhang, Qinxiang Zheng, Xia Li, Chen Zhao, Jijing Pang
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136523 (2015)
To introduce a practical method of subretinal injection in mice and evaluate injection-induced retinal detachment (RD) and damage using a dynamic imaging system, electrophysiology, and histology.After full dilation of a 2-month-old C57BL/6J mouse pup
Externí odkaz:
https://doaj.org/article/25e2c278396e4daf9431b9a9e7a369d2
Publikováno v:
Experimental Eye Research. 179:106-114
The Cacna1f gene encodes the α1F subunit of an L-type voltage-gated calcium channel, Cav1.4. In photoreceptor synaptic terminals, Cav1.4 channels mediate glutamate release and postsynaptic responses associated with visual signal transmission. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e20f60be2abc0f1bbad41d061612751
https://doi.org/10.1016/j.exer.2018.11.010
https://doi.org/10.1016/j.exer.2018.11.010
Publikováno v:
J Biomed Res
Complete congenital achromatopsia is a devastating hereditary visual disorder. Mutations in the CNGB3 gene account for more than 50% of all known cases of achromatopsia. This work investigated the efficiency of subretinal (SR) delivered AAV8 (Y447, 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f32de162422cf9d7cfd54f0994aa5ca
https://pubmed.ncbi.nlm.nih.gov/32305965
https://pubmed.ncbi.nlm.nih.gov/32305965
Autor:
Qinxiang Zheng, Yueping Ren, Radouil Tzekov, Yuanping Zhang, Bo Chen, Jiangping Hou, Chunhui Zhao, Jiali Zhu, Ying Zhang, Xufeng Dai, Shan Ma, Jia Li, Jijing Pang, Jia Qu, Wensheng Li
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44855 (2012)
Leber congenital amaurosis (LCA) is one of the most severe forms of inherited retinal degeneration and can be caused by mutations in at least 15 different genes. To clarify the proteomic differences in LCA eyes, a cohort of retinal degeneration 12 (r
Externí odkaz:
https://doaj.org/article/46865d8a1dc1435f921b3939c729579a