Výsledky vyhledávání - "Jiirgen B. Bulitta"

Penetration of Moxifloxacin into Bone Evaluated by Monte Carlo Simulation

Autor: Jiirgen B. Bulitta, Fritz Sörgel, George L. Drusano, Cornelia B. Landersdorfer, Ulrike Holzgrabe, Johannes Gusinde, Friedrich F. Hennig, Martina Kinzig

Publikováno v: Antimicrobial Agents and Chemotherapy. 53:2074-2081

Moxifloxacin is a fluoroquinolone with a broad spectrum of activity and good penetration into many tissues, including bone. Penetration of moxifloxacin into bone has not yet been studied using compartmental modeling techniques. Therefore, we determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7814a21e5386d80f6779e2559b7c7d7a
https://doi.org/10.1128/aac.01056-08

Zobrazit plný text záznamu

Development and Qualification of a Pharmacodynamic Model for the Pronounced Inoculum Effect of Ceftazidime against Pseudomonas aeruginosa

Autor: William J. Jusko, Alan Forrest, Jiirgen B. Bulitta, Brian T. Tsuji, Jenny C Yang, Neang S. Ly

Publikováno v: Antimicrobial Agents and Chemotherapy. 53:46-56

Pseudomonas aeruginosa is an opportunistic, gram-negative pathogen responsible for high morbidity and mortality (19). P. aeruginosa has multiple mechanisms of resistance to antibiotics, including efflux pumps, the enzymatic degradation of antibiotics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd712fd83643cb7a03c8767914f27ba
https://doi.org/10.1128/aac.00489-08

Zobrazit plný text záznamu

Multiple-pool cell lifespan models for neutropenia to assess the population pharmacodynamics of unbound paclitaxel from two formulations in cancer patients

Autor: Jiirgen B. Bulitta, Ping Zhao, James Pratt, Hans Gelderblom, Richard Daifuku, Robert D. Arnold, Axel-R. Hanauske, Ahmad Awada, Dean R. Kessler, William J. Jusko, Gabriel Luciano

Publikováno v: Cancer Chemotherapy and Pharmacology. 63:1035-1048

Our objective was to build a mechanism-based pharmacodynamic model for the time course of neutropenia in cancer patients following paclitaxel treatment with a tocopherol-based Cremophor-free formulation (Tocosol Paclitaxel) and Cremophor EL-formulate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a282a24147245a2b8e10d097fa316768
https://doi.org/10.1007/s00280-008-0828-1

Zobrazit plný text záznamu

Pharmakokinetik der Chinolone: Wie gut wirken die Gyrasehemmeř

Autor: Jiirgen B. Bulitta, Martina Kinzig-Schippers, Fritz Sörgel

Publikováno v: Pharmazie in unserer Zeit. 30:418-427

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bab1f51bfcb798a687af9789d78dbbf7
https://doi.org/10.1002/1615-1003(200109)30:5<418::aid-pauz418>3.0.co

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání