Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Jiing Kuan Yee"'
Autor:
Nelson Gonzalez, Hiroyuki Kato, Wilma Tixi, Jose Ortiz, Chris Orr, Hung-Ping Shih, Hsun Teresa Ku, Jiing-Kuan Yee, Fouad Kandeel, Yoko Mullen, Eiji Kobayashi, Hirotake Komatsu
Publikováno v:
Cell Transplantation, Vol 32 (2023)
“Firefly rats” ubiquitously express the luciferase reporter gene under the control of constitutively active ROSA26 promoter in inbred Lewis rats. Due to the minimal immunogenicity of luciferase, wide applications of Firefly rats have been reporte
Externí odkaz:
https://doaj.org/article/d9939e4fbe0148df8740c480b1a26889
Autor:
Warren A. Chow, Jiing-Kuan Yee, Walter Tsark, Xiwei Wu, Hanjun Qin, Min Guan, Jeffrey S. Ross, Siraj M. Ali, Sherri Z. Millis
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Desmoplastic small round cell tumor (DSRCT) is a rare, highly aggressive, translocation-associated soft-tissue sarcoma that primarily affects children, adolescents, and young adults, with a striking male predominance. It is charac
Externí odkaz:
https://doaj.org/article/35d14ec047424a06afa9d7b90da0ee59
Publikováno v:
iScience, Vol 22, Iss , Pp 409-422 (2019)
Summary: A major challenge in using human pluripotent stem cells (hPSCs) in therapy is the risk of teratoma formation due to contaminating undifferentiated stem cells. We used CRISPR-Cas9 for in-frame insertion of a suicide gene, iC9, into the endoge
Externí odkaz:
https://doaj.org/article/c1325e2cafec4dfc9b702089adcfe458
Autor:
Bashar Khiatah, Meirigeng Qi, Youjun Wu, Kuan-Tsen Chen, Rachel Perez, Luis Valiente, Keiko Omori, Jeffrey S. Isenberg, Fouad Kandeel, Jiing-Kuan Yee, Ismail H. Al-Abdullah
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
Abstract We developed an optimized Dipheylthiocarbazone or Dithizone (DTZ) with improved physical and chemical properties to characterize human islets and insulin-producing cells differentiated from embryonic stem cells. Application of the newly form
Externí odkaz:
https://doaj.org/article/78b909345c634e4cbdad967487951c3c
Autor:
Anqi Geng, Runxiang Qiu, Kiyohito Murai, Jiancheng Liu, Xiwei Wu, Heying Zhang, Henry Farhoodi, Nam Duong, Meisheng Jiang, Jiing-kuan Yee, Walter Tsark, Qiang Lu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The division of neural progenitors is closely regulated but how is unclear. Here, the authors show that mitotic kinesin KIF20A/MKLP2 interacts with a regulator of G protein signaling RGS3 in neural progenitor cells, dislodging it from the intercellul
Externí odkaz:
https://doaj.org/article/0376cb29837141ebabd45e872751324b
Autor:
Teresa Ubina, Martha Magallanes, Saumya Srivastava, Charles D. Warden, Jiing-Kuan Yee, Paul M. Salvaterra
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
We describe the construction and phenotypic analysis of a human embryonic stem cell model of progressive Aβ-dependent neurodegeneration (ND) with potential relevance to Alzheimer’s disease (AD). We modified one allele of the normal APP locus to di
Externí odkaz:
https://doaj.org/article/2ecfb927a97d47458e1f4fbdfa44373b
Autor:
Yulin Xu, Wei Shan, Xia Li, Binsheng Wang, Senquan Liu, Yebo Wang, Yan Long, Ruxiu Tie, Limengmeng Wang, Shuyang Cai, Hao Zhang, Yu Lin, Mingming Zhang, Weiyan Zheng, Yi Luo, Xiaohong Yu, Jiing-Kuan Yee, Junfeng Ji, He Huang
Publikováno v:
Journal of Hematology & Oncology, Vol 9, Iss 1, Pp 1-16 (2016)
Abstract Background The efficient generation of hematopoietic stem cells (HSCs) from human-induced pluripotent stem cells (iPSCs) holds great promise in personalized transplantation therapies. However, the derivation of functional and transplantable
Externí odkaz:
https://doaj.org/article/5c7d3ea880b6494b839e829347ed5584
Publikováno v:
Molecular Therapy. Nucleic Acids
CRISPR-Cas9 has been developed into a powerful molecular tool for genome engineering, and it has revolutionized the field of biomedical research. Despite the tremendous potential of CRISPR-Cas9 in biomedical research, precise control of CRISPR-Cas9 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32d15658b44395c1066e0c56467c063
https://doi.org/10.1016/j.omtn.2019.12.026
https://doi.org/10.1016/j.omtn.2019.12.026
Autor:
Jeffrey S. Isenberg, Keiko Omori, Meirigeng Qi, Youjun Wu, Luis Valiente, Ismail H. Al-Abdullah, Bashar Khiatah, Jiing-Kuan Yee, Rachel Perez, Kuan-Tsen Chen, Fouad Kandeel
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
Scientific Reports
Scientific Reports
We developed an optimized Dipheylthiocarbazone or Dithizone (DTZ) with improved physical and chemical properties to characterize human islets and insulin-producing cells differentiated from embryonic stem cells. Application of the newly formulated iD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf712f76cf68690332829a775eacfea
https://doaj.org/article/78b909345c634e4cbdad967487951c3c
https://doaj.org/article/78b909345c634e4cbdad967487951c3c
Autor:
Xiaoling Wang, Yingjia Wang, He Huang, Buyuan Chen, Xinji Chen, Jianda Hu, Tammy Chang, Ren-Jang Lin, Jiing-Kuan Yee
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93575 (2014)
The development of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) facilitates in vitro studies of human disease mechanisms, speeds up the process of drug screening, and raises the feasibility of using cell replacement th
Externí odkaz:
https://doaj.org/article/c5c1c4e35de3435f978545385b1409f2