Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jihyun Um"'
Publikováno v:
Molecular Medicine Reports. May2017, Vol. 15 Issue 5, p3035-3040. 6p.
Autor:
Jihyun Um, Je-Hwan Lee, Eun-Hye Huh, So Hee Kim, Sung Hwan Moon, Soojin Lee, Min-Hyo Ki, Dohyeong Lee, Yongbin Park
Publikováno v:
Cancer Research. 81:1430-1430
SJP1604 (APTA-16) is an aptamer-drug conjugate (APTA-DC) specifically targeting nucleolin, which is highly expressed only on the cell membrane of acute myeloid leukemia (AML) cells including relapsed/refractory aute myeloid leukemia (R/R AML). We pre
Autor:
Jihyun Um, Moon Jung Back, Jeongmin Lee, Hyun Tae Kim, Shin You-Keun, Yongbin Park, Hwan Jung Lim, Janghyun Lee, Li-Kyung Kim, Sujin Park, Jae-Woong Lee, Seongjun Park, Kwangwoo Hwang, Jooyoung Hyun, Dohyeong Lee, Min-Hyo Ki, Ho-Seok Kwon, Hei Cheul Jeung
Publikováno v:
Cancer Research. 81:1295-1295
The hippo pathway is a critical transcriptional regulator of cell growth, proliferation, and migration in cancer, furthermore,YAP-TEAD complexes act as a major role in the pathway. S-palmitoylation of cysteine residues in TEAD proteins is required fo
Publikováno v:
Tissue Engineering and Regenerative Medicine. 13:155-161
Dermal fibroblasts play essential roles in wound healing. However, they lose their normal regenerative functions under certain pathologic conditions such as in chronic diabetic wounds. Here, we show that substance P (SP) rescues the malfunctions of d
Publikováno v:
Wound Repair and Regeneration. 24:402-410
Wound healing is essential for the survival and tissue homeostasis of unicellular and multicellular organisms. The current study demonstrated that the neuropeptide substance P (SP) accelerated the wound healing process, particularly in the skin. Subc
Publikováno v:
Cancer Research. 80:5152-5152
Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are cancers characterized by the rapid growth of abnormal white blood cells. Although the standard first-line therapy leads to high rates of remission, approximately 30% of the treated
Autor:
Youngsook Son, Sang-Ho Lee, Nunggum Jung, Sanghyuk Choi, Ki-Sook Park, Jihyun Um, Dong-Jin Kim
Publikováno v:
Biochemical and biophysical research communications. 499(4)
Preservation of pancreatic β-cells is required for the development of therapies for type 1 and type 2 diabetes (T1D and T2D, respectively). Our previous study demonstrated that substance P (SP) preserves β-cell populations in mice with streptozotoc
Publikováno v:
Wound Repair and Regeneration. 23:268-277
Retinal degeneration is caused by neovascularization and persistent inflammation in the retinal pigment epithelium (RPE) and choroid, and causes serious eye disease including age-related macular degeneration (AMD). Thus, inhibiting inflammation and n
Autor:
Dong-Jin Kim, Maria Jose Dubon, Nunggum Jung, Jihyun Um, Ki-Sook Park, Yeji Byeon, Do-Yeon Kim, Youngsook Son
Publikováno v:
Biochemical and biophysical research communications. 491(4)
Preservation of the pancreatic β-cell population is required for the development of therapies for diabetes, which is caused by a decrease in β-cells. Here, we demonstrate the antidiabetic effects of substance P (SP) in type 1 diabetes (T1D) mice in
Autor:
Jihyun Um, Jisun Oh, Su Jin Lee, Yongbin Park, Eui Hwan Cho, Sung Hwan Moon, Dohyeong Lee, Min-Hyo Ki
Publikováno v:
Cancer Research. 79:344-344
Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are cancers characterized by the rapid growth of abnormal white blood cells. Generally, cytarabine (Ara-C), azacitidine, and decitabine are treated as the standard first-line chemothera