Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jihyun Je"'
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Sepsis is a serious clinical condition characterized by a systemic inflammatory response, a leading cause of acute liver and kidney injury, and is associated with a high morbidity and mortality. Understanding the molecular mechanisms underly
Externí odkaz:
https://doaj.org/article/36be7c62e41f4223abf31f1784d88f29
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14295 (2023)
Renal ischemia–reperfusion (IR) causes acute kidney injury due to oxidative stress, tubular inflammation, and apoptosis. Early growth response 1 (Egr-1) is a transcription factor belonging to the immediate early gene family and is known to regulate
Externí odkaz:
https://doaj.org/article/26c4d13bdcf5451f82dd6c4b2effb33f
Autor:
Eun Jung Park, Jihyun Je, Theodomir Dusabimana, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3413 (2023)
Renal ischemia reperfusion (IR) injury is a major cause of acute kidney injury (AKI) that is often complicated by multiple organ failure of the liver and intestine. The mineralocorticoid receptor (MR) is activated in patients with renal failure assoc
Externí odkaz:
https://doaj.org/article/de44260743b2432abf49b5c3b566335a
Autor:
Eun Jung Park, Jihyun Je, Theodomir Dusabimana, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3048 (2022)
Homocysteine (Hcy), a homologue of cysteine, is biosynthesized during methionine metabolism. Elevated plasma Hcy is associated with glomerular injury and considered as a risk factor for renal dysfunction, predicting incident chronic kidney disease. H
Externí odkaz:
https://doaj.org/article/54f06cca08c542e2a47c2a7b8475a6e6
Autor:
Bina Lee, Ingabire Ines, Jihyun Je, Eun Jung Park, Hyemin Seong, Min Gi Jo, Hwajin Kim, Seon-Hee Kim, Seong Jae Kim, Hye Jung Kim, Minkyeong Kim, Sang Won Park, Seung Pil Yun
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2993 (2022)
Acute kidney injury (AKI) is an inflammatory sequence. It can lead to distant organ injury, including damage to the central nervous system (CNS), mediated by increased circulating cytokines and other inflammatory mediators. It can also lead to increa
Externí odkaz:
https://doaj.org/article/47201f43b98c4174aac53dfe24611afe
Autor:
Theodomir Dusabimana, So Ra Kim, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
Molecular Metabolism, Vol 42, Iss , Pp 101089- (2020)
Objective: Diabetic nephropathy (DN) is one of the most common complications of diabetes and a critical risk factor for developing end-stage renal disease. Activation of purinergic receptors, including P2Y2R has been associated with the pathogenesis
Externí odkaz:
https://doaj.org/article/a2941e251b6042079222d83568b7c0fc
Autor:
Hwajin Kim, So Ra Kim, Jihyun Je, Kyuho Jeong, Sooji Kim, Hye Jung Kim, Ki Churl Chang, Sang Won Park
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-17 (2018)
Kidney injury: Nicotine and inflammation Nicotine may protect the kidney against ischemic reperfusion (IR) injury by reducing inflammation. IR injury is the tissue damage caused by a temporary block of blood flow leading to lack of oxygen and nutrien
Externí odkaz:
https://doaj.org/article/5e94409b29c54f9797498fd32c96a22c
Autor:
Jihyun Je, Miyoung Song, Ji Hyeong Baek, Jae Soon Kang, Hye Jin Chung, Kwonsu Lee, Sang Won Park, Hyun Joon Kim
Publikováno v:
Nutrients, Vol 13, Iss 12, p 4404 (2021)
Hovenia dulcis, known as the oriental raisin tree, is used for food supplements and traditional medicine for the liver after alcohol-related symptoms. However, little information exists about the use of its leaves and branches. In this study, we esta
Externí odkaz:
https://doaj.org/article/621678b2cf9d433882adcfe5a5f685d4
Autor:
Theodomir Dusabimana, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5528 (2021)
Non-alcoholic fatty liver disease (NAFLD) is a chronic metabolic liver disease associated with obesity and insulin resistance. Activation of the purinergic receptor P2Y2R has been reported to promote adipogenesis, inflammation and dyslipidemia in adi
Externí odkaz:
https://doaj.org/article/9d0185334f6443ab9bebdce696872902
Autor:
Theodomir Dusabimana, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1651 (2021)
Diabetic nephropathy (DN) is a common pathological feature in patients with diabetes and the leading cause of end-stage renal disease. Although several pharmacological agents have been developed, the management of DN remains challenging. Geniposide,
Externí odkaz:
https://doaj.org/article/3e740c6f338b4141937ea911e3649768